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Nature Chemistry, ISSN 1755-4330, 07/2018, Volume 10, Issue 7, pp. 755 - 762
The development of a Pd(II)-catalysed enantioselective fluorination of C(sp(3))-H bonds would offer a new approach to making chiral organofluorines. However,... 
PD-IV | FUNCTIONALIZATION | ACTIVATION | C-H FLUORINATION | COMPLEXES | CHEMISTRY | ALPHA-AMINO-ACIDS | BOND | CHEMISTRY, MULTIDISCIPLINARY | FLUORIDE | TRIFLUOROMETHYLATION | Insertion | Stereochemistry | Enantiomers | Fluorination | Bonding
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2016, Volume 55, Issue 31, pp. 8923 - 8927
The fluorination of unactivated C(sp3)−H bonds remains a desirable and challenging transformation for pharmaceutical, agricultural, and materials scientists.... 
fluorination | C−H activation | uranium | photocatalysis | hydrogen atom transfer | COMPLEXES | TOLUENE | ION | CHEMISTRY, MULTIDISCIPLINARY | C-H BONDS | MEDICINAL CHEMISTRY | C-H activation | ROLES | MOLECULAR-OXYGEN | Hydrogen | Catalysis
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 1900, Volume 137, Issue 22, pp. 7067 - 7070
A quinoline-based ligand was shown to promote palladium-catalyzed β-C­(sp3)–H fluorination for the first time. A range of unnatural enantiopure fluorinated... 
PALLADIUM | C(SP)-H | C-H FLUORINATION | REDUCTIVE ELIMINATION | CHEMISTRY, MULTIDISCIPLINARY | ARYLATION | Amino Acids - chemistry | Amino Acids - chemical synthesis | Stereoisomerism | Fluorine - chemistry | Palladium catalysts | Alanine | Research | Chemical properties | Chemical synthesis
Journal Article
ACS Catalysis, ISSN 2155-5435, 2015, Volume 5, Issue 5, pp. 2846 - 2849
A facile and site-selective C–H bond fluorination of phenols using removable 2-pyridyloxy group as an auxiliary was developed. Alternatively, late-stage C–H... 
phenols | catalysis | nicotinates | C-H bond fluorination | late-stage fluorination | CATALYZED FLUORINATION | ACTIVATION | ACID | DIVERSIFICATION | ALPHA-ARYLATION | CHEMISTRY, PHYSICAL | CLEAVAGE | 2-PHENOXYPYRIDINES | FUNCTIONALIZATION | OLEFINATION | BORYLATION
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2018, Volume 57, Issue 36, pp. 11812 - 11816
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 09/2016, Volume 14, Issue 36, pp. 8398 - 8427
Fluorination reactions of medicinal and biologically-active compounds will be discussed. Late stage fluorination strategies of medicinal targets have recently... 
Hydrocarbons, Fluorinated - chemical synthesis | Hydrocarbons, Fluorinated - chemistry | Molecular Structure | Drug Discovery | Fluorine - chemistry | Halogenation
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 9/2016, Volume 14, Issue 36, pp. 8398 - 8427
Fluorination reactions of medicinal and biologically-active compounds will be discussed. Late stage fluorination strategies of medicinal targets have recently... 
MEDICINAL CHEMISTRY | REMOVABLE DIRECTING GROUPS | COPPER-MEDIATED FLUORINATION | POSITRON-EMISSION-TOMOGRAPHY | ANTI-HIV ACTIVITY | ELECTROPHILIC FLUORINATION | C-H FLUORINATION | FLUOROPYRIDINIUM SALT SYSTEM | CHEMISTRY, ORGANIC | LATE-STAGE FLUORINATION | METAL-FREE
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2014, Volume 53, Issue 39, pp. 10330 - 10335
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2018, Volume 57, Issue 43, pp. 14085 - 14089
Selective introduction of fluorine into molecules by the cleavage of inert C−H bonds is of central academic and synthetic interest, yet remains challenging.... 
fluorination | palladium | alcohols | C−H activation | synthetic methods | CATALYSIS | ACTIVATION | F BOND | ALPHA-AMINO-ACIDS | CARBON-HYDROGEN BONDS | REDUCTIVE ELIMINATION | CHEMISTRY, MULTIDISCIPLINARY | FLUORIDE | DIRECTING GROUPS | FUNCTIONALIZATION | C-H activation | C-H FLUORINATION | Organic chemistry | Hydrogen bonds | Fluorine | Alcohol | Fluorination | Alcohols | Acetone
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 04/2014, Volume 53, Issue 18, pp. 4690 - 4693
Journal Article
Organic Letters, ISSN 1523-7060, 05/2013, Volume 15, Issue 9, pp. 2160 - 2163
A direct conversion of C(sp3)–H bonds to C(sp3)–F bonds has been developed. In this process, a catalytic N-oxyl radical generated from... 
MEDICINAL CHEMISTRY | FUNCTIONALIZATION | OXIDATION | BENZYLIC FLUORINATION | PHARMACEUTICALS | C-H FLUORINATION | ELEMENTAL FLUORINE | ORGANIC-COMPOUNDS | CHEMISTRY, ORGANIC | HYDROXYPHTHALIMIDE | MOLECULES | Hydrogen Bonding | Metals - chemistry | Halogenation | Molecular Structure | Catalysis | Carbon - chemistry | Fluorine - chemistry
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2018, Volume 57, Issue 31, pp. 9896 - 9900
Journal Article