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BLOOD, ISSN 0006-4971, 08/2016, Volume 128, Issue 7, pp. 923 - 933
Bipotent megakaryocyte/erythroid progenitors (MEPs) give rise to progeny limited to the megakaryocyte (Mk) and erythroid (E) lineages. We developed a novel... 
MYELOID PROGENITOR | HUMAN C-MPL | HEMATOPOIETIC STEM-CELLS | LINE | GATA-1 | DIFFERENTIATION | LEUKEMIA | THROMBOPOIETIN | HEMATOLOGY | EXPRESSION | REVEALS
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 09/2017, Volume 17, Issue 9, pp. 573 - 590
Journal Article
Journal Article
BLOOD, ISSN 0006-4971, 03/2019, Volume 133, Issue 13, pp. 1427 - 1435
The classical model of hematopoiesis proposes a hierarchy in which a small number of multipotent hematopoietic stem cells (HSCs) maintain all blood lineages by... 
MYELOID PROGENITOR | STIMULATION | HEMATOPOIETIC STEM-CELLS | TRANSCRIPTION | BIOLOGY | SELF-RENEWAL | PLATELET PRODUCTION | C-MPL LIGAND | IDENTIFICATION | HEMATOLOGY | EXPRESSION
Journal Article
BLOOD, ISSN 0006-4971, 01/2012, Volume 119, Issue 1, pp. 83 - 94
Throughout life, one's blood supply depends on sustained division of hematopoietic stem cells (HSCs) for self-renewal and differentiation. Within the bone... 
PROGENITOR CELLS | ACTIVATION | INTEGRIN ALPHA(IIB)BETA | COMPETITIVE REPOPULATION | BONE-MARROW NICHE | RECEPTOR | C-MPL | HEMATOLOGY | BINDING | MICE LACKING | BETA
Journal Article
BLOOD, ISSN 0006-4971, 12/2016, Volume 128, Issue 26, pp. 3146 - 3158
The mechanisms behind the hereditary thrombocytosis induced by the thrombopoietin (THPO) receptor MPL P106L mutant remain unknown. A complete trafficking... 
POLYCYTHEMIA-VERA | JAK2 V617F | CONGENITAL AMEGAKARYOCYTIC THROMBOCYTOPENIA | PLATELETS | MUTATION | MUTANT CALRETICULIN | MYELOPROLIFERATIVE NEOPLASMS | C-MPL | HEMATOLOGY | EXPRESSION | THROMBOPOIETIN RECEPTOR
Journal Article
BLOOD, ISSN 0006-4971, 12/2014, Volume 124, Issue 26, pp. 3956 - 3963
The most frequent contributing factor in Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) is the acquisition of a V617F mutation in Janus... 
MYELOFIBROSIS | POLYCYTHEMIA-VERA | ACTIVATING MUTATION | CONGENITAL AMEGAKARYOCYTIC THROMBOCYTOPENIA | HEMATOPOIETIC STEM-CELLS | TYROSINE KINASE JAK2 | C-MPL | HEMATOLOGY | EXPRESSION | MYELOID METAPLASIA | TRANSGENIC MICE
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 08/2008, Volume 118, Issue 8, pp. 2832 - 2844
In addition to its role in megakaryocyte production, signaling initiated by thrombopoietin (TPO) activation of its receptor, myeloproliferative leukemia virus... 
MEDICINE, RESEARCH & EXPERIMENTAL | POLYCYTHEMIA-VERA | ACTIVATION | ERYTHROPOIETIN RECEPTOR | SURFACE EXPRESSION | LNK | C-MPL | DEFICIENT MICE | THROMBOPOIETIN | MEMBRANE-PROXIMAL REGION | TRANSPLANTATION
Journal Article
Blood, ISSN 0006-4971, 03/2014, Volume 123, Issue 12, pp. 1818 - 1825
Journal Article