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Biochemical journal, ISSN 1470-8728, 2010, Volume 431, Issue 2, pp. 217 - 225
In mammalian cells, MCTs (monocarboxylate transporters) require association with an ancillary protein to enable plasma membrane expression of the active... 
Basigin | Erythrocyte | Monocarboxylate transporter 2 (MCT2) | Embigin | Lactate transport | Monocarboxylate transporter 1 (MCT1) | IMMUNOGLOBULIN SUPERFAMILY | TRANSMEMBRANE HELICES | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | lactate transport | PLASMA-MEMBRANE | erythrocyte | SKELETAL-MUSCLE | BASIGIN CD147 | monocarboxylate transporter 1 (MCT1) | embigin | monocarboxylate transporter 2 (MCT2) | basigin | EXPRESSION | LACTIC-ACID EFFLUX | RETINAL-PIGMENT EPITHELIUM | Recombinant Proteins - metabolism | Rabbits | Lactic Acid - metabolism | Glycoproteins - metabolism | Rats | Thiophenes - pharmacology | Symporters - chemistry | Erythrocytes - drug effects | Oocytes - cytology | Uracil - pharmacology | Monocarboxylic Acid Transporters - antagonists & inhibitors | Animals | Xenopus laevis - metabolism | Mutant Proteins - chemistry | Symporters - antagonists & inhibitors | Erythrocytes - metabolism | Basigin - metabolism | Oocytes - drug effects | Xenopus Proteins - metabolism | Kinetics | Mutant Proteins - antagonists & inhibitors | Monocarboxylic Acid Transporters - chemistry | Uracil - analogs & derivatives | WT, wild-type | MCT, monocarboxylate transporter | TM, transmembrane | YFP, yellow fluorescent protein | FRET, fluorescence resonance energy transfer | 2c, MCT1 with MCT2 C-terminus | EST, expressed sequance tag | MCT1trn, MCT1 without C-terminus | RT, reverse transcription | 1c, MCT2 with MCT1 C-terminus | BCECF, 2′,7′-bis-(2-carboxyethyl)-5-carboxyfluorescein | HA, haemagglutinin | MCT2 | MCT2trn, MCT2 without C-terminus | pCMBS, p-chloromercuribenzene sulfonate | MCT1 | CFP, cyan fluorescent protein
Journal Article
Trends in cell biology, ISSN 0962-8924, 2014, Volume 24, Issue 2, pp. 90 - 99
Highlights • The circadian clock generates molecular rhythms with 24 h periodicity. • Circadian control of physiology is distributed to peripheral tissues. •... 
Pathology | peripheral clock | circadian | transcription | post-transcription | Post-transcription | Transcription | Circadian | Peripheral clock | PROTEIN | C-TERMINUS | CRYSTAL-STRUCTURE | MOUSE | BODY-TEMPERATURE | CELL BIOLOGY | EXCISION-REPAIR | TRANSCRIPTIONAL-REGULATION | GENE-EXPRESSION | REV-ERB-ALPHA | FEEDBACK | Animals | Circadian Rhythm | Circadian Clocks - physiology | Humans | Proteins | Physiological aspects
Journal Article
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1 - 13
The interaction of hC5a with C5aR, previously hypothesized to involve a “two-site” binding, (i) recognition of the bulk of hC5a by the N-terminus (NT) of C5aR... 
C-Terminus | Free energy | N-Terminus | PharmacoPhores
Journal Article
Journal Article
Journal of cellular and molecular medicine, ISSN 1582-4934, 2019, Volume 23, Issue 12, pp. 8442 - 8452
Ichthyosis with confetti (IWC) is a genodermatosis associated with dominant‐negative variants in keratin 10 (KRT10) or keratin 1 (KRT1). These frameshift... 
carboxy terminus | arginine‐rich C‐terminus | nuclear localization | ichthyosis with confetti | KRT10 | alanine‐rich C‐terminus | keratin 10 | Keratins | Translocation | Alanine | Antibodies | Amino acids | Glycine | Patients | Nuclear transport | Ichthyosis | Proteins | Genodermatosis | Keratin | Arginine | Plasmids | Immunofluorescence | Localization | Genetic modification | Cytoplasm | Original
Journal Article
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 14
Knots in proteins are hypothesized to make them resistant to enzymatic degradation by ATP-dependent proteases and recent studies have shown that whereas ClpXP... 
Proteins | C-Terminus | Intermediates
Journal Article
PLoS genetics, ISSN 1553-7404, 10/2018, Volume 14, Issue 10, p. e1007768
[This corrects the article DOI: 10.1371/journal.pgen.1007489.]. 
Architecture | Gene mutations | Germ cells | Immunoprecipitation | Clonal deletion | Alleles | Myc protein | C-Terminus | Localization | Embryos
Journal Article
Biochemical journal, ISSN 0264-6021, 01/2012, Volume 441, Issue 1, pp. 399 - 406
Beclin 1, a subunit of the class III phosphatidylinositol 3-kinase complex, is a tumour suppressor with a central role in endocytic trafficking, cytokinesis... 
Phosphoinositide | Ubiquitination | VPS34 | Neural-precursor-cell-expressed developmentally down-regulated 4 (Nedd4) | Homologous with E6-associated protein C-terminus (HECT) | Cancer | WW DOMAINS | N4WBP5A | COMPLEX | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | neural-precursor-cell-expressed developmentally down-regulated 4 (Nedd4) | E3 UBIQUITIN LIGASES | AUTOPHAGY | INDUCTION | homologous with E6-associated protein C-terminus (HECT) | phosphoinositide | ubiquitination | cancer | PHYSIOLOGICAL FUNCTIONS | REVEALS | Beclin-1 | Membrane Proteins - genetics | Humans | Endosomal Sorting Complexes Required for Transport - metabolism | Ubiquitin - chemistry | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Endosomal Sorting Complexes Required for Transport - genetics | Gene Expression Regulation - physiology | Phosphatidylinositol 3-Kinases - metabolism | Apoptosis Regulatory Proteins - metabolism | Phosphatidylinositol 3-Kinases - genetics | Class III Phosphatidylinositol 3-Kinases - genetics | Proteolysis | Apoptosis Regulatory Proteins - genetics | Nedd4 Ubiquitin Protein Ligases | Membrane Proteins - metabolism | HeLa Cells | Protein Stability | Ubiquitin-Protein Ligases - genetics | HECT, homologous with E6-associated protein C-terminus | CCD, coiled-coil domain | ECD, evolutionarily conserved domain | CHX, cycloheximide | HA, haemagglutinin | DTT, dithiothreitol | siRNA, small interfering RNA | AIP4, atrophin-interacting protein 4 | HRP, horseradish peroxidase | Ub, ubiquitin | DMEM, Dulbecco's modified Eagle's medium | Nedd4, neural-precursor-cell-expressed developmentally down-regulated 4 | BH3, Bcl-2 homology 3 | PI3K-III, class III PI 3-kinase | GST, glutathione transferase | TRAF6, tumour-necrosis-factor-receptor-associated factor 6
Journal Article
Journal Article