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Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 5/2013, Volume 110, Issue 21, pp. 8650 - 8655
.... This versatile recognition protein senses a wide variety of immune and nonimmune ligands, including pathogens and altered self components, and triggers the classical complement pathway... 
Proteins | Molecules | Cell lines | Materials | Cell aggregates | Ligands | Mass spectroscopy | Biochemistry | Electron microscopy | Molecular chains | C1 complex | Protein engineering | Innate immunity | B-CHAIN | ACTIVATION | 1ST COMPONENT | PROTEIN | MULTIDISCIPLINARY SCIENCES | LONG PENTRAXIN PTX3 | LIGAND-RECOGNITION | MANNAN-BINDING LECTIN | protein engineering | innate immunity | STRUCTURAL BASIS | PATHWAY | SUBCOMPONENT C1Q | Surface Plasmon Resonance | Complement C1r - genetics | Calcium - metabolism | Humans | Complement C1s - metabolism | Mutation, Missense | Complement C1q - metabolism | Complement C1r - metabolism | Complement C1s - genetics | Complement C1r - chemistry | Complement C1s - chemistry | C-Reactive Protein - metabolism | HEK293 Cells | Protein Structure, Quaternary | Binding Sites | Complement C1q - chemistry | Complement Activation - physiology | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Gene Expression | Immunoglobulin G - chemistry | Serum Amyloid P-Component - chemistry | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Complement C1q - genetics | C-Reactive Protein - chemistry | Serum Amyloid P-Component - metabolism | Amino Acid Substitution | Immunoglobulin G - metabolism | Protein Binding - physiology | Bone morphogenetic proteins | Polypeptides | Research | Properties | Proteases | Protein binding | C-Reactive Protein | Calcium | Complement Activation | Immunoglobulin G | Biochemistry, Molecular Biology | Serum Amyloid P-Component | Recombinant Proteins | Complement C1q | Complement C1s | Complement C1r | Life Sciences | Protein Binding | Biomolecules | Biological Sciences
Journal Article
by Kaptoge, Stephen and Angelantonio, Emanuele and Pennells, Lisa and Wood, Angela and White, Ian and Gao, Pei and Walker, Mark and Thompson, Alexander and Sarwar, Sheryar and Caslake, Muriel and Butterworth, Adam and Amouyel, Philippe and Assmann, Gerd and Bakker, Stephan and Barr, E.L.M and Barrett-Connor, Elizabeth and Benjamin, Emelia and Björkelund, Cecilia and Brenner, Hermann and Brunner, Eric and Clarke, Robert and Cooper, Jackie and Cremer, P and Cushman, Mary Ann and Dagenais, Gilles R and D'Agostino, Ralph and Dankner, Rachel and Davey-Smith, George and Deeg, Dorly and Dekker, Jacqueline and Engström, G and Folsom, Aaron and Fowkes, F. Gerald R and Gallacher, John and Gaziano, J. Michael and Giampaoli, Simona and Gillum, Richard and Hofman, Albert and Howard, Barbara and Ingelsson, Erik and Iso, Hiroyasu and Jorgensen, Torben and Kiechl, Stefan and Kitamura, A and Kiyohara, Yutaka and Koenig, Wolfgang and Kromhout, Daan and Kuller, Lewis and Lawlor, Debbie and Meade, Tom and Nissinen, Aulikki and Nordestgaard, Børge and Onat, Altan and Panagiotakos, Demosthenes and Psaty, Bruce and Roiguez, Beatriz and Rosengren, Annika and Salomaa, Veikko and Kauhanen, Jussi and Salonen, J.T and Shaffer, Jonathan and Shea, Steven and Ford, Ian and Stehouwer, Coen and Strandberg, Timo and Tipping, Alex and Tosetto, Alberto and Wassertheil-Smoller, Sylvia and Wennberg, Patrik and Westendorp, Rudi and Whincup, Peter and Wilhelmsen, Lars and Woodward, Mark and Lowe, Gordon and Wareham, Nick and Khaw, Kay-Tee and Sattar, Naveed and Packard, Chris and Gudnason, Vilmundur and Ridker, Paul and Pepys, Mark and Thompson, Simon and Danesh, John and The Emerging Risk Factors Collaboration and Emerging Risk Factors and Emerging Risk Factors Collaboration and Sahlgrenska akademin and Institute of Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för medicin
The New England journal of medicine, ISSN 1533-4406, 2012, Volume 367, Issue 14, pp. 1310 - 1320
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Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2004, Volume 279, Issue 47, pp. 48487 - 48490
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Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 10/2004, Volume 95, Issue 9, pp. 877 - 883
C-reactive protein (CRP), a characteristic inflammatory marker, is a powerful predictor of cardiovascular events... 
Lectin-like oxidized low-density lipoprotein receptor-1 | Inflammation | C-reactive protein | Endothelium | endothelium | CARDIAC & CARDIOVASCULAR SYSTEMS | LOW-DENSITY-LIPOPROTEIN | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | INDUCTION | RELEASE | OX-LDL | INTERLEUKIN-6 | ADHESION | OXIDIZED LDL RECEPTOR-1 | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | lectin-like oxidized low-density lipoprotein receptor-1 inflammation | NF-KAPPA-B | Endothelium, Vascular - cytology | Anti-Infective Agents - pharmacology | Cells, Cultured - cytology | Humans | Scavenger Receptors, Class E | Endothelium, Vascular - drug effects | RNA, Messenger - biosynthesis | Inflammation - metabolism | C-Reactive Protein - pharmacology | Nitriles | Lipoproteins, LDL - metabolism | Sulfones | Intercellular Adhesion Molecule-1 - analysis | Receptors, LDL - genetics | Cells, Cultured - drug effects | NF-kappa B - antagonists & inhibitors | Leukocytes, Mononuclear - drug effects | Endothelial Cells - metabolism | Receptors, Oxidized LDL | Glucose - pharmacology | C-Reactive Protein - physiology | Cell Adhesion - drug effects | Gene Expression Regulation - drug effects | Interleukin-6 - pharmacology | Endothelial Cells - cytology | Endothelium, Vascular - metabolism | Receptors, LDL - biosynthesis | Lipopolysaccharides - pharmacology | Aorta - cytology | Receptors, LDL - physiology | Vascular Cell Adhesion Molecule-1 - analysis | E-Selectin - analysis | Endothelial Cells - drug effects
Journal Article
FEBS Letters, ISSN 0014-5793, 2009, Volume 583, Issue 9, pp. 1415 - 1421
Transcription is activated by signal-induced protein–protein interaction between transcription factors on regulatory elements positioned near their target genes... 
RNA aptamer | β-Catenin | C-reactive protein | Nuclear factor-κB | nuclear factor-κB | CRP | NF-κB | TNF-α | tumor necrosis factor-α | Nuclear factor-kappa B | BINDS | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | beta-Catenin | COLON | TCF4 | WNT | CELL BIOLOGY
Journal Article