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Nature Genetics, ISSN 1061-4036, 11/2016, Volume 48, Issue 11, pp. 1349 - 1358
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2007, Volume 371, Issue 3, pp. 608 - 621
C2 domains are conserved protein modules in many eukaryotic signaling proteins, including the protein kinase (PKCs). The C2 domains of classical PKCs bind to... 
PtdIns(4,5)P 2 | GFP | phosphatidylserine | PKC | C2 domain | PROTEIN-KINASE-C | ACTIVATION | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | INFRARED-SPECTROSCOPY | PLASMA-MEMBRANE | SIGNAL-TRANSDUCTION | PtdIns(4,5)P-2 | CA2 | CALCIUM | PHOSPHATIDIC-ACID
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 2006, Volume 1761, Issue 8, pp. 838 - 849
Journal Article
Structure, ISSN 0969-2126, 12/2018, Volume 26, Issue 12, pp. 1612 - 1625.e4
Phosphorylation of phosphoinositides by the class II phosphatidylinositol 3-kinase (PI3K) PI3K-C2α is essential for many processes, including neuroexocytosis... 
PX domain | C2 domain | PI3-kinase | protein-lipid interactions | phosphoinositides | SYSTEM | PI3K-C2-ALPHA | ACTIVATION | CHANNEL KCA3.1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | CELL BIOLOGY | 3-KINASE C2-ALPHA | BIOPHYSICS | PHOX-HOMOLOGY DOMAIN | PI3K | CLATHRIN | INSIGHTS
Journal Article
BIOPHYSICAL JOURNAL, ISSN 0006-3495, 08/2019, Volume 117, Issue 3, pp. 479 - 489
The von Willebrand factor (VWF) and coagulation factor VIII (FVIII) are intricately involved in hemostasis. A tight, noncovalent complex between VWF and FVIII... 
VONWILLEBRAND-FACTOR | PROTEIN | BIOPHYSICS | AFFINITY BINDING-SITE | FACTOR VWF | RECOMBINANT | NMR-SPECTROSCOPY | COAGULATION-FACTOR-VIII | LIGHT-CHAIN | C2 DOMAIN | DISEASE | Nuclear magnetic resonance spectroscopy | Blood coagulation factor VIII | Von Willebrand factor | Hemophilia
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 04/2009, Volume 50, Issue Supplement, pp. S299 - S304
The spatial and temporal regulation of lipid molecules in cell membranes is a hallmark of cellular signaling and membrane trafficking events. Lipid-mediated... 
C2 domain | Peripheral protein | C1 domain | PLECKSTRIN HOMOLOGY DOMAINS | ACTIVATION | MECHANISM | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE-C-ALPHA | PH DOMAINS | MEMBRANE-BINDING | BAR | peripheral protein | DRUG DEVELOPMENT | PHOSPHATIDIC-ACID | Lipid Metabolism | Animals | Signal Transduction | Binding Sites | Humans | Membranes and Lipid Domains
Journal Article