X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (826) 826
animals (781) 781
index medicus (599) 599
immunology (451) 451
mice (406) 406
complement (368) 368
c5a (350) 350
inflammation (318) 318
male (306) 306
activation (261) 261
female (235) 235
complement activation (229) 229
complement c5a - metabolism (217) 217
biochemistry & molecular biology (180) 180
c5a receptor (174) 174
expression (172) 172
complement c5a - antagonists & inhibitors (171) 171
complement c5a - pharmacology (163) 163
mice, inbred c57bl (163) 163
complement c5a - immunology (161) 161
disease models, animal (160) 160
rats (160) 160
receptor, anaphylatoxin c5a - metabolism (154) 154
receptor, anaphylatoxin c5a - antagonists & inhibitors (145) 145
cell biology (144) 144
receptor (143) 143
anaphylatoxin (136) 136
complement component c5a (133) 133
proteins (130) 130
neutrophils (129) 129
cells, cultured (128) 128
receptor, anaphylatoxin c5a (127) 127
mice, knockout (119) 119
article (116) 116
complement c5a (115) 115
neutrophils - immunology (112) 112
neutrophils - drug effects (111) 111
pharmacology & pharmacy (109) 109
analysis (104) 104
signal transduction (101) 101
neutrophils - metabolism (98) 98
receptor, anaphylatoxin c5a - genetics (96) 96
cytokines (94) 94
cells (92) 92
research (92) 92
receptors, complement - metabolism (88) 88
receptors, complement - antagonists & inhibitors (86) 86
amino acid sequence (83) 83
sepsis (83) 83
medicine, research & experimental (82) 82
molecular sequence data (82) 82
c3a (81) 81
in vitro techniques (80) 80
research article (79) 79
c5a receptor antagonist (77) 77
physiological aspects (76) 76
inhibition (75) 75
mice, inbred balb c (74) 74
middle aged (74) 74
rodents (74) 74
innate immunity (73) 73
neutrophils - physiology (73) 73
abridged index medicus (72) 72
identification (72) 72
complement c5a - physiology (71) 71
anaphylatoxins (70) 70
chemical and pharmacologic phenomena (70) 70
peptides, cyclic - pharmacology (70) 70
apoptosis (69) 69
hematology (69) 69
immune system (68) 68
receptor, anaphylatoxin c5a - immunology (68) 68
adult (67) 67
ischemia-reperfusion injury (67) 67
pathology (67) 67
inflammation - immunology (66) 66
complement system (65) 65
disease (65) 65
cell line (64) 64
medicine (64) 64
neurosciences (64) 64
respiratory system (64) 64
chemotaxis (63) 63
in-vivo (63) 63
n-formylmethionine leucyl-phenylalanine - pharmacology (63) 63
anaphylatoxin c5a (62) 62
endothelial-cells (62) 62
leukocytes (61) 61
gene expression (60) 60
multidisciplinary sciences (59) 59
time factors (59) 59
tumor-necrosis-factor (59) 59
pathogenesis (58) 58
binding (57) 57
flow cytometry (57) 57
health aspects (57) 57
ligands (57) 57
macrophages (57) 57
dose-response relationship, drug (56) 56
enzyme-linked immunosorbent assay (56) 56
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1372) 1372
Japanese (16) 16
Chinese (4) 4
Dutch (2) 2
German (2) 2
French (1) 1
Hebrew (1) 1
Italian (1) 1
Korean (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Structural and Molecular Biology, ISSN 1545-9993, 06/2018, Volume 25, Issue 6, pp. 472 - 481
Journal Article
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 02/2013, Volume 27, Issue 2, pp. 822 - 831
Mammalian survival depends on metabolizing nutrients, storing energy, and combating infection. Complement activation in blood triggers energy-depleting immune... 
Adipose inflammation | GPCR | Complement | Metabolism | Immunity | CELLS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | adipose inflammation | immunity | DEFICIENCY | INFILTRATION | CELL BIOLOGY | LIPOLYSIS | INSULIN-RESISTANCE | INFLAMMATION | BIOLOGY | metabolism | complement | ADIPOSE-TISSUE | Rats, Wistar | Obesity - immunology | Receptors, Complement - antagonists & inhibitors | Diet, High-Fat - adverse effects | Metabolic Diseases - immunology | Male | Peptides, Cyclic - pharmacology | Adipocytes - drug effects | Lipid Metabolism - immunology | Arginine - analogs & derivatives | Signal Transduction - immunology | Obesity - etiology | Adipocytes - immunology | Macrophages - immunology | Dietary Carbohydrates - administration & dosage | Rats | Inflammation - immunology | 3T3-L1 Cells | Obesity - metabolism | Macrophages - metabolism | Animals | Metabolic Diseases - metabolism | Signal Transduction - drug effects | Metabolic Diseases - etiology | Adipocytes - metabolism | Arginine - pharmacology | Obesity - prevention & control | Lipid Metabolism - drug effects | Macrophages - drug effects | Benzhydryl Compounds - pharmacology | Inflammation - prevention & control | Metabolic Diseases - prevention & control | Mice | Dietary Carbohydrates - adverse effects | Receptor, Anaphylatoxin C5a - antagonists & inhibitors
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 10/2018, Volume 18, Issue 10, pp. 2417 - 2428
Journal Article
Scientific Reports, ISSN 2045-2322, 04/2016, Volume 6, Issue 1, p. 24575
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 01/2020, Volume 63, Issue 2, pp. 529 - 541
Structure-activity relationships for a series of small-molecule thiophenes resulted in potent and selective antagonism of human Complement C3a receptor. The... 
CHEMISTRY, MEDICINAL | PROTEIN | LIGANDS | ANAPHYLATOXINS | REGULATORS | AGONISTS | C5A
Journal Article
Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7686, pp. 111 - 114
The complement system is a crucial component of the host response to infection and tissue damage. Activation of the complement cascade generates anaphylatoxins... 
ACID | SMALL-MOLECULE | OPIOID RECEPTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | GPCR | OLIGOMERIZATION | IDENTIFICATION | Receptor, Anaphylatoxin C5a - chemistry | Receptor, Anaphylatoxin C5a - genetics | Protein Structure, Secondary | Receptors, G-Protein-Coupled - metabolism | Humans | Imidazoles - chemistry | Benzodioxoles - metabolism | Models, Molecular | Crystallography, X-Ray | Imidazoles - pharmacology | Receptors, Adrenergic, beta-2 - metabolism | Receptors, Adrenergic, beta-2 - chemistry | Animals | Drug Inverse Agonism | HEK293 Cells | Benzodioxoles - chemistry | Mutation | Protein Stability | Receptor, Anaphylatoxin C5a - antagonists & inhibitors | Binding Sites | Benzodioxoles - pharmacology | Receptors, G-Protein-Coupled - chemistry | Imidazoles - metabolism | Receptor, Anaphylatoxin C5a - metabolism | Drugs | Inflammatory bowel diseases | G protein-coupled receptors | Peptides | Complement component C5a | Manufacturing engineering | Complement | Antagonists | Helices | Arthritis | Production costs | Receptors | Reperfusion | Ischemia | Anaphylatoxins | Alzheimer's disease | Neurodegenerative diseases | Psoriasis | Medical treatment | Crystallization | Inflammation | Crohn's disease | Bioavailability | Mode of action | Complement activation | Immunogenicity | Rheumatoid arthritis | Sepsis | Ligands
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2012, Volume 189, Issue 11, pp. 5442 - 5448
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 06/2014, Volume 27, Issue 6, pp. 857 - 864
BACKGROUND Inflammatory responses mediate the development of perivascular fibrosis and heart dysfunction induced by hypertension. Complement is an important... 
cardiovascular damage | blood pressure | complement | inflammation | hypertension | FIBROSIS | TGF-BETA | ATHEROSCLEROSIS | RECEPTOR | COMPLEMENT FACTOR C5A | T-CELL | FIBROBLASTS | C3A | INHIBITION | PERIPHERAL VASCULAR DISEASE | Transforming Growth Factor beta1 - metabolism | Cardiomegaly - pathology | Hypertension - drug therapy | Peptides, Cyclic - pharmacology | RNA, Messenger - metabolism | Time Factors | Hypertension - chemically induced | Myocardium - metabolism | Angiotensin II | Cytokines - genetics | Disease Models, Animal | Cytokines - metabolism | Mice, Inbred C57BL | Cardiomegaly - physiopathology | Myocardium - pathology | Transforming Growth Factor beta1 - genetics | Hypertension - pathology | Hypertension - physiopathology | Cardiovascular Agents - pharmacology | Hypertension - metabolism | Collagen - metabolism | Animals | Cardiomegaly - prevention & control | Fibrosis | Cardiomegaly - chemically induced | Connective Tissue Growth Factor - genetics | Receptor, Anaphylatoxin C5a - antagonists & inhibitors | Ventricular Remodeling - drug effects | Connective Tissue Growth Factor - metabolism | Cardiomegaly - metabolism | Receptor, Anaphylatoxin C5a - metabolism | Hypertension | Prevention | Complications and side effects | Protease inhibitors | Patient outcomes | Angiotensin | Development and progression | Dosage and administration | Cardiovascular diseases | Health aspects | Risk factors | Heart | Cytokines | Fibroblasts | Cardiomyocytes | Inflammation | Blood pressure | Gene expression | Growth factors | Asthma
Journal Article