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PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, p. e0157830
The ability of Natural Killer (NK) cells to kill tumor targets has been extensively studied in various hematological malignancies. However, NK cell therapy... 
DEPENDENT CELLULAR CYTOTOXICITY | KRAS MUTATIONS | COLON-CANCER | GROWTH-FACTOR RECEPTOR | LUNG-CANCER | NATURAL-KILLER-CELLS | POLYMORPHISMS | MULTIDISCIPLINARY SCIENCES | ANTI-EGFR THERAPY | MONOCLONAL-ANTIBODY | HLA-E | Caco-2 Cells | ras Proteins - genetics | ErbB Receptors - antagonists & inhibitors | Killer Cells, Natural | Colorectal Neoplasms - genetics | Humans | ErbB Receptors - genetics | Cell- and Tissue-Based Therapy | HT29 Cells | Neoplasm Metastasis | Antibodies, Monoclonal, Humanized - administration & dosage | Colorectal Neoplasms - immunology | Immunoglobulin G - immunology | Proto-Oncogene Proteins B-raf - genetics | Colorectal Neoplasms - drug therapy | Cetuximab - administration & dosage | Cell Proliferation - drug effects | Mutation | Antibodies, Monoclonal, Humanized - immunology | Colorectal Neoplasms - pathology | Therapy | Biotechnology | Toxicity | Immunoglobulin G | Colorectal carcinoma | Colorectal cancer | Cytotoxicity | Oncology | Metastasis | Metastases | Receptors | Colon cancer | Epidermal growth factor | Immunotherapy | Peripheral blood | Colon | Natural killer cells | Immunoglobulins | Hematology | Epidermal growth factor receptors | Tumor cells | Cell division | Ras protein | Tumor cell lines | Fc receptors | CD16 antigen | Medical prognosis | Cell lines | Monoclonal antibodies | Solid tumors | Cancer | Tumors
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180190
Journal Article
Cell Biology and Toxicology, ISSN 0742-2091, 1/2005, Volume 21, Issue 1, pp. 1 - 26
The human intestinal Caco-2 cell line has been extensively used over the last twenty years as a model of the intestinal barrier. The parental cell line,... 
Life Sciences | Biochemistry, general | clonal cell lines | culture conditions | differentiation | transporters | Caco-2 | Pharmacology/Toxicology | biotransformation activities | Cell Biology | Transporters | Biotransformation activities | Differentiation | Clonal cell lines | Culture conditions | MESSENGER-RNA EXPRESSION | COLON-CARCINOMA-CELLS | VITAMIN-D-RECEPTOR | SERUM-FREE MEDIUM | CARRIER-MEDIATED TRANSPORT | CELL BIOLOGY | TRANSIENT MOSAIC PATTERNS | EPITHELIAL-CELLS | EPIDERMAL-GROWTH-FACTOR | TOXICOLOGY | NA+/H+ EXCHANGERS NHE2 | ENTEROCYTIC DIFFERENTIATION | Clone Cells - cytology | Clone Cells - drug effects | Cell Count | Humans | Clone Cells - physiology | Extracellular Matrix - metabolism | Cell Culture Techniques - methods | Intestinal Mucosa - drug effects | Intestinal Mucosa - cytology | Paracrine Communication - physiology | Sucrase-Isomaltase Complex - metabolism | Membrane Transport Proteins - metabolism | Culture Media - chemistry | Cell Differentiation - physiology | Caco-2 Cells | Enterocytes - cytology | Autocrine Communication - physiology | Cell Physiological Phenomena | Cell Adhesion - drug effects | Intestinal Mucosa - physiology | Enterocytes - drug effects | Cell Adhesion - physiology | Cell Differentiation - drug effects | Culture Media - pharmacology | Enterocytes - physiology | Evaluation | Cell research | Research | Cell transformation | Nutrition | Cells
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2015, Volume 28, Issue 6, pp. 815 - 829
Hierarchical organization of tissues relies on stem cells, which either self-renew or produce committed progenitors predestined for lineage differentiation.... 
β-catenin | cancer stem cells | MYC | retinoids | Retinoids | Cancer stem cells | INTESTINAL EPITHELIUM | HOMEOSTASIS | RETINOIC ACID | PROTEIN | ONCOLOGY | PATHWAY | GENE-EXPRESSION | RECEPTOR | PROLIFERATION | BETA-CATENIN | CELL BIOLOGY | Intestinal Mucosa - metabolism | Cell Proliferation | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Homeodomain Proteins - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Phosphoproteins - metabolism | Neoplasm Metastasis | Transfection | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Cell Transformation, Neoplastic - genetics | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Neoplastic Stem Cells - pathology | Female | Antineoplastic Agents - pharmacology | Cell Differentiation | Tumor Cells, Cultured | Colorectal Neoplasms - metabolism | Caco-2 Cells | Tissue Culture Techniques | HCT116 Cells | Mice, Inbred C57BL | Mice, Transgenic | Phosphoproteins - genetics | Cell Transformation, Neoplastic - metabolism | Homeodomain Proteins - genetics | HT29 Cells | Feedback, Physiological | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Aged | Cell Transformation, Neoplastic - pathology | Colorectal Neoplasms - pathology | Retinoids - pharmacology | Intestinal Mucosa - pathology | Development and progression | Developmental biology | Colorectal cancer | Stem cells | Prevention | Resveratrol | Transplantation | Metastasis | Cancer
Journal Article
Journal Article
MOLECULES, ISSN 1420-3049, 06/2018, Volume 23, Issue 6, p. 1471
Here and for the first time, we show that the organometallic compound [Ru(eta(5)-C5H5)(PPh3)(2)Cl] (RuCp) has potential to be used as a metallodrug in... 
toxicity | cancer treatment | CURRENT CLINICAL-USES | hMSCs | dendrimers | BIOCHEMISTRY & MOLECULAR BIOLOGY | nanocarriers | nanomedicine | OVARIAN-CANCER | CHEMISTRY, MULTIDISCIPLINARY | ruthenium | ANTICANCER ACTIVITY | LUNG-CANCER | NAMI-A | platinum | KP1019 | ARENE RUTHENIUM COMPLEXES | HALF-SANDWICH RHODIUM | metallodrugs | cisplatin | PHASE-I | Caco-2 Cells | Cell Survival - drug effects | Antineoplastic Agents - chemical synthesis | Humans | Epithelial-Mesenchymal Transition - drug effects | Cisplatin - pharmacology | Antineoplastic Agents - chemistry | Coordination Complexes - chemistry | Dendrimers | MCF-7 Cells | Organometallic Compounds - chemical synthesis | Mesenchymal Stem Cells - cytology | Mesenchymal Stem Cells - drug effects | Cell Line, Tumor | Coordination Complexes - chemical synthesis | Coordination Complexes - pharmacology | Organometallic Compounds - chemistry | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | Organometallic Compounds - pharmacology | Drug Resistance, Neoplasm - drug effects | Drug Screening Assays, Antitumor | Ovarian carcinoma | Mesenchyme | Toxicity | Organometallic compounds | Stem cells | Cell lines | Tumor cell lines | Drug resistance | Cisplatin | Tumors | Cancer | Drugs | Clinical trials | Cytotoxicity | Metastasis | Cancer therapies | Ligands | Nanostructured materials | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | Cancer and Oncology | Cancer och onkologi
Journal Article
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2008, Volume 183, Issue 4, pp. 625 - 633
The establishment of apical--basal polarity within a single cell and throughout a growing tissue is a key feature of epithelial morphogenesis. To examin