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The Journal of Physiology, ISSN 0022-3751, 03/2017, Volume 595, Issue 5, pp. 1657 - 1670
We report that the small molecule CK‐2066260 selectively slows the off‐rate of Ca 2 + from fast skeletal muscle troponin, leading to increased myofibrillar Ca... 
troponin C | skeletal muscle | sensitivity | FIBERS | OBSTRUCTIVE PULMONARY-DISEASE | PHYSIOLOGY | CONTRACTION | MOTOR UNITS | CALCIUM | RELAXATION | MOUSE MUSCLE | BINDING | NEUROSCIENCES | DIAPHRAGM MUSCLE | TROPONIN | Skeletal Muscle | Muscular Conditions, Disorders and Treatments | Research Paper | Muscle | Ca2+ sensitivity | Muscle Physiology
Journal Article
Biochemistry, ISSN 0006-2960, 11/2016, Volume 55, Issue 43, pp. 6032 - 6045
The binding of Ca2+ to cardiac troponin C (cTnC) triggers contraction in heart muscle. In the diseased heart, the myocardium is often desensitized to Ca2+,... 
MAGNETIC-RESONANCE DETERMINATION | PROTEIN-LIGAND COMPLEXES | FAILING HEART | CATHEPSIN-K | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | CARDIOTONIC AGENT | MEDIATED CALCIUM SENSITIZATION | PARAMAGNETIC RELAXATION ENHANCEMENT | MOLECULAR-STRUCTURE DETERMINATION | REGULATORY DOMAIN
Journal Article
Journal Article
Anesthesiology Clinics, ISSN 1932-2275, 12/2010, Volume 28, Issue 4, pp. 753 - 760
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 2017, Volume 39, Issue 8, pp. e35 - e36
During rewarming of hypothermic patients, ventricular arrhythmias and cardiac arrest is however a lethal complication contributing to 30-40% mortality in this... 
Internal Medicine | Medical Education | Analysis | Hypothermia | Heart | Cardiac arrhythmia | Animals | Calcium | Rodents | In vivo methods and tests | Ventricle | Heart diseases
Journal Article
European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, 8/2008, Volume 34, Issue 2, pp. 326 - 331
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2014, Volume 307, Issue 11, pp. H1605 - H1617
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2010, Volume 160, Issue 1, pp. 142 - 152
Journal Article