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Journal Article
2008, ISBN 9780123694485, xv, 473 p., [27] p. of plates
The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes... 
Antineoplastic agents | Clinical & internal medicine | Design | Development
Book
Anti-cancer drugs, ISSN 0959-4973, 1990
Journal
2007, 1. Aufl., Ernst Schering Research Foundation workshop, ISBN 9783540278672, Volume 59., xvi, 216
Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to... 
Drugs | Drug development | Drug testing | Dose-response relationship | Cancer | Biochemistry | Biochemistry, general | Biomedicine | Pharmacology/Toxicology | Medicine/Public Health, general
Book
2008, 1. Aufl., Cancer drug discovery and development series, ISBN 1934115290, xxi, 419
Book
2004, ISBN 9780471432029, 362
Molecular Cancer Therapeutics covers state-of-the-art strategies to identify and develop cancer drug target molecules and lead inhibitors for clinical testing.... 
Design | Chemotherapy | Antineoplastic agents | Immunotherapy | Cancer | Cancer - Immunotherapy
eBook
Investigational new drugs, ISSN 0167-6997, 1983
Journal
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7547, pp. 368 - 372
Drug resistance invariably limits the clinical efficacy of targeted therapy with kinase inhibitors against cancer(1,2). Here we show that targeted therapy with... 
CNS CELL-TYPES | MELANOMA | METASTASIS | MICROENVIRONMENT | TRANSLATIONAL PROFILING APPROACH | MULTIDISCIPLINARY SCIENCES | RAF INHIBITOR RESISTANCE | ACQUIRED-RESISTANCE | KINASE INHIBITORS | DRUG-RESISTANCE | CANCER CHEMORESISTANCE | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Clone Cells - drug effects | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Proto-Oncogene Proteins c-fos - deficiency | Adenocarcinoma - metabolism | Neoplasm Metastasis - drug therapy | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Proto-Oncogene Proteins c-akt - metabolism | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | Melanoma - pathology | Down-Regulation - drug effects | Enzyme Activation - drug effects | Adenocarcinoma - drug therapy | Disease Progression | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Cell Movement - drug effects | Lung Neoplasms - secretion | Melanoma - secretion | Animals | Clone Cells - pathology | Metabolome - drug effects | Signal Transduction - drug effects | Neoplasm Metastasis - pathology | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Adenocarcinoma - secretion | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Pharmaceutical research | Care and treatment | Oncology, Experimental | Dosage and administration | Research | Drug therapy | Drug resistance | Antineoplastic agents | Tumors | Cancer | Melanoma | Mutation | Metastasis | Kinases | Cancer therapies | Index Medicus
Journal Article
Journal Article