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Clinical and Experimental Hypertension, ISSN 1064-1963, 11/2019, Volume 41, Issue 8, pp. 747 - 752
BACKGROUND: We hypothesized that the 5-oxo-1,2,4-oxadiazole moiety of azilsartan (AZL), which represents a small difference in the molecular structures of AZL... 
5-oxo-1-oxadiazole | Arg | azilsartan | candesartan
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 03/2019, Volume 33, Issue 3
This study pointed to estimate the possible protective impacts of candesartan and/or epigallocatechin-3-gallate (EGCG) against gentamicin-induced... 
Catechin | Candesartan | Aminoglycosides | Mitogens
Journal Article
Acta Pharmaceutica, ISSN 1330-0075, 03/2019, Volume 69, Issue 1, pp. 63 - 74
Development of safe and effective drugs requires complete impurity evaluation and, therefore, knowledge about the formation and elimination of impurities is... 
synthesis | HRMS | candesartan cilexetil (TCV-116) | impurity | diastereoisomers | candesartan cilexetil ( TCV-116) | PHARMACOLOGY & PHARMACY | Candesartan cilexetil | Target recognition | Nuclear magnetic resonance--NMR | Synthesis | Impurities | Imidazole | Analyzers | Biphenyl | Liquid chromatography | Drug development | Carbonyls
Journal Article
Brain Research, ISSN 0006-8993, 07/2000, Volume 871, Issue 1, pp. 29 - 38
Brain Angiotensin II, through stimulation of brain AT sub(1) receptors, regulates pituitary hormones and autonomic activity. We have administered the... 
Candesartan
Journal Article
Asian Journal of Pharmaceutics, ISSN 0973-8398, 07/2018, Volume 12, Issue 3, pp. 196 - 203
Context: Cocrystal technique is a novel approach for altering the physicochemical properties of an active pharmaceutical ingredient (API). Pharmaceutical... 
Candesartan | Dissolution | Cocrystal | Solubility | Acids
Journal Article
European Heart Journal, ISSN 0195-668X, 05/2013, Volume 34, Issue 19, pp. 1404 - 1413
Using a large international database from multiple cohort studies, the aim is to create a generalizable easily used risk score for mortality in patients with... 
Heart failure | Prognostic model | Mortality | Meta-analysis | VENTRICULAR EJECTION FRACTION | CARDIAC & CARDIOVASCULAR SYSTEMS | MODEL | TRIAL | DISCHARGE | MORBIDITY | CANDESARTAN | SYSTOLIC DYSFUNCTION | PROGRAM | Female | Male | Epidemiologic Methods | Humans | Middle Aged | Heart Failure - mortality | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2011, Volume 149, Issue 2, pp. 168 - 174
Journal Article
Asian Pacific journal of cancer prevention : APJCP, ISSN 1513-7368, 06/2017, Volume 18, Issue 6, pp. 1629 - 1636
Background: Carboplatin is a drug that is used for treatment of many types of cancer. However, it may produce serious nephrotoxicity. Candesartan is... 
coenzyme Q10 | nephrotoxicity | Candesartan | mice | carboplatin
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 12/2009, Volume 17, Issue 23, pp. 7971 - 7977
[ C]Methyl-candesartan and its desethyl derivative ([ C]TH4) were developed as potential radiotracers for imaging angiotensin II (Ang II) type 1 (AT )... 
C]Desethyl-candesartan | C]Methyl-candesartan | [ | PET imaging | C]Radiolabeling
Journal Article
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 05/2015, Volume 3, Issue 5, pp. 316 - 316
Journal Article
Drug Development and Industrial Pharmacy, ISSN 0363-9045, 07/2019, Volume 45, Issue 7, pp. 1140 - 1148
The objective of this study was to improve candesartan cilexetil (CC) efficacy by formulating nanocrystals via solid dispersion (SD) technique using... 
prodrug | tromethamine | Candesartan | solid dispersion | bioavailability | candesartan cilexetil | VITRO | LIPID NANOPARTICLES | CHEMISTRY, MEDICINAL | WATER-SOLUBLE DRUG | FORMULATION | MELT EXTRUDATE | ENHANCED DISSOLUTION | RELEASE MECHANISM | TABLETS | ORAL BIOAVAILABILITY | PHARMACOLOGY & PHARMACY | ABSORPTION
Journal Article
Obstetrics & Gynecology, ISSN 0029-7844, 09/2019, Volume 134, Issue 3, pp. 481 - 484
BACKGROUND:There are currently no data regarding the transfer of candesartan into human milk. This report provides data on this transfer, an estimation of the... 
Candesartan | Physiological aspects | Drug therapy | Mothers | Health aspects | Contamination | Breast milk | Index Medicus | Abridged Index Medicus
Journal Article
International Journal of Pharmaceutical Sciences and Research, ISSN 0975-8232, 12/2015, Volume 6, Issue 12, p. 5198
Journal Article
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, 04/2015, Volume 140, pp. 210 - 215
Two different methods manipulating spectrophotometric data have been developed, validated and compared. One is capable of removing the signal of any... 
Hydrochlorothiazide | Irbesartan | Spectrophotometry | Candesartan | MCR | CRACLS | DERIVATIVE SPECTROPHOTOMETRY | HUMAN PLASMA | SPECTROSCOPY | HPLC METHOD | CANDESARTAN CILEXETIL | MULTIVARIATE CALIBRATION
Journal Article
by Saglimbene, Valeria and Palmer, Suetonia C and Ruospo, Marinella and Natale, Patrizia and Maione, Ausilia and Nicolucci, Antonio and Vecchio, Mariacristina and Tognoni, Gianni and Craig, Jonathan C and Pellegrini, Fabio and Lucisano, Giuseppe and Hegbrant, Jörgen and Ariano, Rosario and Lamacchia, Olga and Sasso, Antonio and Morano, Susanna and Filardi, Tiziana and De Cosmo, Salvatore and Pugliese, Giuseppe and Procaccini, Deni A and Gesualdo, Loreto and Palasciano, Giuseppe and Johnson, David W and Tonelli, Marcello and Strippoli, Giovanni F.M and Cignarelli, Mauro and Di Mauro, Maurizio and Tonolo, Giancarlo and Adinolfi, Luigi Elio and Gigante, Alfonso and Carboni, Luciano and Anichini, Roberto and Marino, Cecilia and Querques, Mario and Manfrini, Silvana and Cianciaruso, Bruno and Grandaliano, Giuseppe and Prato, Stefano Del and Giorgino, Francesco and Perin, Paolo Cavallo and Malberti, Fabio and Nardo, Alfio and Invitti, Cecilia and Panettieri, Immacolata and Bono-mini, Mario and Sesti, Giorgio and Altomare, Emanuele and Giordano, Rosa and Iacono, Alessandro and Lusenti, Tiziano and Jovane, Carlo and Zavaroni, Ivana and Vernaglione, Luigi and Grosso, Juliette and Stratta, Piero and Andriani, Antonia and Montanaro, Alessio and Ciaula, Agostino Di and Triolo, Giorgio and Santoro, Antonio and Spada, Silvio and Benedetto, Antonio Di and Borzì, Vito and Tortul, Carla and Schiavoni, Mario and Cavalera, Cesare and Iannarelli, Rossella and Mileti, Giovanni and Tardi, Salvatore and Di Rosa, Salvatore and Long-Term Impact RAS and Long-Term Impact of RAS Inhibition on Cardiorenal Outcomes (LIRICO) Investigators and on behalf of the Long-Term Impact of RAS Inhibition on Cardiorenal Outcomes (LIRICO) Investigators
Journal of the American Society of Nephrology, ISSN 1046-6673, 12/2018, Volume 29, Issue 12, pp. 2890 - 2899
Background The comparative effectiveness of treatment with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or their... 
TELMISARTAN | RAMIPRIL | DOUBLE-BLIND | UROLOGY & NEPHROLOGY | RISK | CANDESARTAN | TYPE-2 | BLOOD-PRESSURE | ENALAPRIL | VALSARTAN | Index Medicus
Journal Article
European Heart Journal, ISSN 0195-668X, 6/2008, Volume 29, Issue 11, pp. 1377 - 1385
Aims To determine whether the risk of adverse cardiovascular (CV) outcomes associated with diabetes differs in patients with low and preserved ejection... 
VENTRICULAR SYSTOLIC DYSFUNCTION | MORTALITY | heart failure | CAPACITY | CARDIAC & CARDIOVASCULAR SYSTEMS | ABNORMALITIES | CLINICAL CHARACTERISTICS | MELLITUS | MORBIDITY | CANDESARTAN | diabetes | ASSOCIATION | PROGRAM
Journal Article
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, ISSN 1011-601X, 05/2019, Volume 32, Issue 3, pp. 1019 - 1024
To compare the pharmacokinetics of candesartan cilexetil in healthy male and female volunteers in order to identify possible influence of gender and to improve... 
Candesartan cilexetil | LOSARTAN | gender | RATIONALE | SAFETY | pharmacokinetics | PHARMACOLOGY & PHARMACY | PHARMACODYNAMICS | hypertension | HYPERTENSIVE PATIENTS | HEMODYNAMICS | Treatment outcome | Usage | Candesartan | Analysis | Research | Pharmacokinetics | High performance liquid chromatography
Journal Article
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