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1. Full Text The peripheral CB1 receptor antagonist JD5037 attenuates liver fibrosis via a CB1 receptor/β‐arrestin1/Akt pathway
by Tan, Siwei and Liu, Huiling and Ke, Bilun and Jiang, Jie and Wu, Bin
British journal of pharmacology, ISSN 0007-1188, 06/2020, Volume 177, Issue 12, pp. 2830 - 2847
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Stellate cells | Signal transduction | Animal models | Liver diseases | Liver | Fibrosis | AKT protein | Cannabinoid CB1 receptors | Morbidity | Bile | Index Medicus
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2. Full Text Mitochondrial CB1 receptors regulate neuronal energy metabolism
by Benard, Giovanni and Massa, Federico and Puente, Nagore and Lourenco, Joana and Bellocchio, Luigi and Soria-Gomez, Edgar and Matias, Isabel and Delamarre, Anna and Metna-Laurent, Mathilde and Cannich, Astrid and Hebert-Chatelain, Etienne and Mulle, Christophe and Ortega-Gutierrez, Silvia and Martin-Fontecha, Mar and Klugmann, Matthias and Guggenhuber, Stephan and Lutz, Beat and Gertsch, Juerg and Chaouloff, Francis and Lopez-Rodriguez, Maria Luz and Grandes, Pedro and Rossignol, Rodrigue and Marsicano, Giovanni
Nature neuroscience, ISSN 1097-6256, 04/2012, Volume 15, Issue 4, pp. 558 - 564
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Animals, Newborn | Cricetinae | Cricetulus | Mitochondrial Membranes - physiology | Cells, Cultured | Rats | Male | Mitochondria - metabolism | Receptor, Cannabinoid, CB1 - physiology | Mice, Knockout | Mitochondrial Membranes - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Animals | Neurons - physiology | Female | Mice | Neurons - metabolism | Energy Metabolism - physiology | Mitochondria - physiology | CHO Cells | Index Medicus
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3. Full Text Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures — A short review
by Svíženská, Ivana and Dubový, Petr and Šulcová, Alexandra
Pharmacology, biochemistry and behavior, ISSN 0091-3057, 2008, Volume 90, Issue 4, pp. 501 - 511
Nervous system | Endocannabinoid system | CB receptors | Cannabinoid | Therapeutic potential | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Behavioral Sciences | Science & Technology | Biological and medical sciences | Medical sciences | Cannabinoid Receptor Modulators - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Cannabinoids - therapeutic use | Animals | Receptor, Cannabinoid, CB1 - agonists | Receptor, Cannabinoid, CB2 - agonists | Humans | Nervous System - metabolism | Ligands | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Glaucoma | Physiological aspects | Enzymes | Analgesics | Epilepsy | Atherosclerosis | Index Medicus
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4. Full Text Real‐time characterization of cannabinoid receptor 1 (CB1) allosteric modulators reveals novel mechanism of action
by Cawston, Erin E and Redmond, William J and Breen, Courtney M and Grimsey, Natasha L and Connor, Mark and Glass, Michelle
British journal of pharmacology, ISSN 0007-1188, 10/2013, Volume 170, Issue 4, pp. 893 - 907
internalization | receptor signalling | cannabinoid receptor | desensitization | allosteric modulator | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Humans | Cannabinoid Receptor Agonists - pharmacology | Dose-Response Relationship, Drug | Cyclohexanols - metabolism | Transfection | Piperidines - pharmacology | HEK293 Cells | Cannabinoid Receptor Antagonists - pharmacology | Indoles - pharmacology | Cyclohexanols - pharmacology | Cyclic AMP - metabolism | Potassium Channels, Inwardly Rectifying - drug effects | Rats | Protein Transport | Receptor, Cannabinoid, CB1 - metabolism | Animals | Receptor, Cannabinoid, CB1 - genetics | Membrane Potentials | Signal Transduction - drug effects | Receptor, Cannabinoid, CB1 - drug effects | Cell Line, Tumor | Ligands | Mice | Phenylurea Compounds - pharmacology | Pyridines - pharmacology | Kinetics | Potassium Channels, Inwardly Rectifying - metabolism | Cyclohexanol | Urea | Chemical properties | Studies | Binding sites | Index Medicus | Research Papers
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5. Full Text Cannabinoid CB1 and CB2 Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson’s Disease
by Navarrete, Francisco and García-Gutiérrez, M Salud and Aracil-Fernández, Auxiliadora and Lanciego, José L and Manzanares, Jorge
Neurotherapeutics, ISSN 1933-7213, 4/2018, Volume 15, Issue 2, pp. 459 - 469
Immunohistochemistry | Neurology | Neurosciences | Basal ganglia | Biomedicine | Neurobiology | CB1 and CB2 receptor | MAGL | Neurosurgery | Gene expression | Parkinson’s disease | Pharmacology & Pharmacy | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Microglia - metabolism | Gene Expression | Humans | Middle Aged | Basal Ganglia - metabolism | Male | Substantia Nigra - metabolism | Monoacylglycerol Lipases - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Dopaminergic Neurons - metabolism | Aged, 80 and over | Adult | Female | Aged | Parkinson Disease - metabolism | Astrocytes - metabolism | Putamen - metabolism | Parkinson's disease | Neurodegenerative diseases | Neuropathology | Astrocytes | Substantia nigra | Parkinsons disease | Cannabinoid CB1 receptors | Lipase | Ribonucleic acid--RNA | Putamen | Microglia | Polymerase chain reaction | Endocannabinoid system | Microglial cells | Cannabinoid CB2 receptors | Localization | Movement disorders | Index Medicus | Original
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6. Full Text Crystal Structure of the Human Cannabinoid Receptor CB1
by Hua, Tian and Vemuri, Kiran and Pu, Mengchen and Qu, Lu and Han, Gye Won and Wu, Yiran and Zhao, Suwen and Shui, Wenqing and Li, Shanshan and Korde, Anisha and Laprairie, Robert B and Stahl, Edward L and Ho, Jo-Hao and Zvonok, Nikolai and Zhou, Han and Kufareva, Irina and Wu, Beili and Zhao, Qiang and Hanson, Michael A and Bohn, Laura M and Makriyannis, Alexandros and Stevens, Raymond C and Liu, Zhi-Jie and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Cell (Cambridge), ISSN 0092-8674, 10/2016, Volume 167, Issue 3, pp. 750 - 762.e14
G protein-coupled receptor | cannabinoid receptor CB1 | AM6538 | rimonabant | cell signalling | crystal structure | marijuana | stabilizing antagonist | THC | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
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