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Biochemical Journal, ISSN 0264-6021, 12/2010, Volume 432, Issue 2, pp. 249 - 254
GSD-1 (glycogen storage disease type 1) is caused by an inherited defect in glucose-6-phosphatase activity, resulting in a massive accumulation of hepatic... 
Pentose-5-phosphate pathway | Carbohydrate-response-element-binding protein (ChREBP) | Glycogen storage disease type 1 (GSD-1) | Sterol-regulatory element-binding protein-1c (SREBP-1c) | Glucose 6-phosphate | Liver X receptor (LXR) | GLUCOSE-6-PHOSPHATASE | sterol-regulatory element-binding protein-1c (SREBP-1c) | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | DEFICIENCY | NUCLEAR RECEPTOR | METABOLISM | STEATOSIS | INSULIN-RESISTANCE | GLUCOSE | liver X receptor (LXR) | glucose 6-phosphate | carbohydrate-response-element-binding protein (ChREBP) | pentose-5-phosphate pathway | MICE | glycogen storage disease type 1 (GSD-1) | ACUTE INHIBITION | Glucose-6-Phosphatase - genetics | Liver - enzymology | Humans | Transcription Factors - deficiency | Imidazoles - administration & dosage | Male | Orphan Nuclear Receptors - metabolism | RNA - genetics | RNA - isolation & purification | Glucose-6-Phosphatase - adverse effects | Liver Glycogen - metabolism | Glycogen Storage Disease - enzymology | Liver X Receptors | Nuclear Proteins - deficiency | Nuclear Proteins - genetics | Disease Models, Animal | Pyridines - administration & dosage | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Nuclear Proteins - metabolism | Glycogen Storage Disease - metabolism | Imidazoles - pharmacology | Transcription Factors - genetics | Cholesterol - metabolism | Orphan Nuclear Receptors - genetics | Glucose-6-Phosphatase - metabolism | Mice, Knockout | Triglycerides - metabolism | Transcription Factors - metabolism | Orphan Nuclear Receptors - deficiency | Animals | Glycogen Storage Disease - genetics | Mice | Pyridines - pharmacology | Index Medicus
Journal Article
Journal Article
Bioscience Reports, ISSN 0144-8463, 12/2018, Volume 38, Issue 6, p. BSR20180767
Diabetic nephropathy (DN) is one of the most devastating complications of diabetes mellitus. Carbohydrate response element binding protein (ChREBP) is a basic... 
INDUCED DIABETIC-NEPHROPATHY | LIPOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | FAT DIET | DYSFUNCTION | INSIGHTS | CELL BIOLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/1999, Volume 274, Issue 50, pp. 35832 - 35839
To elucidate the physiological role of sterol regulatory element-binding protein-1 (SREBP-1), the hepatic mRNA levels of genes encoding various lipogenic... 
DIFFERENTIATION FACTOR-1 | CARBOHYDRATE RESPONSE ELEMENT | MESSENGER-RNA | UPSTREAM STIMULATORY FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTIVATED RECEPTOR-ALPHA | PYRUVATE-KINASE GENE | MOLECULAR-CLONING | FATTY-ACID SYNTHASE | LEUCINE ZIPPER PROTEIN | TRANSGENIC MICE | Cholesterol - blood | Hydroxymethylglutaryl-CoA Synthase - genetics | Acetyl-CoA Carboxylase - genetics | DNA-Binding Proteins - deficiency | CCAAT-Enhancer-Binding Proteins | DNA-Binding Proteins - metabolism | Fatty Acid Synthases - biosynthesis | Nuclear Proteins - deficiency | Fatty Acids, Nonesterified - blood | Female | Nuclear Proteins - genetics | Fatty Acid Synthases - genetics | Eating | Fasting | Liver - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Enzyme Induction | Nuclear Proteins - metabolism | Hydroxymethylglutaryl CoA Reductases - biosynthesis | Transcription Factors - genetics | Cholesterol - metabolism | DNA-Binding Proteins - genetics | Stearoyl-CoA Desaturase - genetics | Mice, Knockout | Triglycerides - metabolism | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Stearoyl-CoA Desaturase - biosynthesis | Animals | Animal Nutritional Physiological Phenomena | Diet | Triglycerides - blood | Acetyl-CoA Carboxylase - biosynthesis | Mice | Sterol Regulatory Element Binding Protein 1 | Hydroxymethylglutaryl CoA Reductases - genetics | Sterol Regulatory Element Binding Protein 2 | glucose-6-phosphate dehydrogenase | sterol regulatory element-binding protein 1 | Glycerol-3-phosphate acyltransferase | ATP citrate | SREBP-1 protein | Index Medicus
Journal Article
Physiological Reports, ISSN 2051-817X, 03/2016, Volume 4, Issue 6, pp. 1 - n/a
Persistent high concentration of glucose causes cellular stress and damage in diabetes via derangement of gene expressions. We previously reported high glucose... 
transcription factor | mesangial cells | Carbohydrate response element‐binding protein | diabetic nephropathy | platelet‐derived growth factor‐C | Mesangial cells | Carbohydrate response element-binding protein | Diabetic nephropathy | Platelet-derived growth factor-C | Transcription factor | Up-Regulation | Diabetic Nephropathies - etiology | Humans | Collagen Type VI - metabolism | Male | Diabetic Nephropathies - blood | Platelet-Derived Growth Factor - genetics | Collagen Type VI - genetics | Diabetes Mellitus, Experimental - blood | Lymphokines - genetics | Transfection | RNA Interference | Time Factors | Lymphokines - metabolism | Diabetes Mellitus, Experimental - complications | Nuclear Proteins - genetics | Binding Sites | Collagen Type IV - metabolism | Diabetic Nephropathies - urine | Lymphokines - urine | Cell Line | Promoter Regions, Genetic | Diabetic Nephropathies - pathology | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Mesangial Cells - metabolism | Transcription Factors - genetics | Platelet-Derived Growth Factor - urine | Transcription Factors - metabolism | Platelet-Derived Growth Factor - metabolism | Animals | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Mesangial Cells - pathology | Collagen Type IV - genetics | Protein Binding | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Blood Glucose - metabolism | Proteins | Diabetes | Glucose | Gene expression | Growth factors | Rodents | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2001, Volume 98, Issue 24, pp. 13710 - 13715
Recently we purified and identified a previously uncharacterized transcription factor from rat liver binding to the carbohydrate responsive element of the... 
Proteins | Biological Sciences | Phosphorylation | Transcription factors | Transcriptional regulatory elements | Hepatocytes | Genetic vectors | Genes | Liver | DNA | Experimental procedures | ACTIVATION | FRUCTOSE 2,6-BISPHOSPHATE | PROMOTER | NUCLEUS | MULTIDISCIPLINARY SCIENCES | LIVER | Leucine Zippers | Phosphoprotein Phosphatases - metabolism | Molecular Sequence Data | Male | Helix-Loop-Helix Motifs | Threonine - metabolism | DNA-Binding Proteins - metabolism | Isoquinolines - pharmacology | Threonine - genetics | Transcription, Genetic | Binding Sites | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Amino Acid Sequence | Cantharidin - pharmacology | Response Elements | Carbohydrate Metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Serine - genetics | Phosphoprotein Phosphatases - antagonists & inhibitors | DNA - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Rats, Sprague-Dawley | Serine - metabolism | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Protein Kinase Inhibitors | Animals | Mutagenesis | Sulfonamides | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Glucose - metabolism | Bucladesine - pharmacology | Mice | Subcellular Fractions | Pyruvate Kinase - genetics | Physiological aspects | Enzymes | Protein metabolism | Regulation | Genetic transcription | Carbohydrates | Rodents | Glucose | ChREBP protein | carbohydrate response element-binding protein | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2016, Volume 291, Issue 29, pp. 15378 - 15387
The Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in many physiological processes. Several studies indicate that AHR is... 
MESSENGER-RNA | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER | GENE-EXPRESSION | ALPHA | MICE | LIGAND | TARGET GENE | TRANSCRIPTION FACTOR | FGF21 | Humans | Fibroblast Growth Factors - genetics | Male | Fibroblast Growth Factors - biosynthesis | Hepatocytes - metabolism | Hepatocytes - cytology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Receptors, Aryl Hydrocarbon - metabolism | Energy Metabolism - physiology | Nuclear Proteins - genetics | Response Elements - physiology | Cell Line | Basic Helix-Loop-Helix Transcription Factors - genetics | Receptors, Aryl Hydrocarbon - genetics | Gene Expression Regulation - physiology | Nuclear Proteins - metabolism | PPAR alpha - genetics | Transcription Factors - genetics | Mice, Knockout | Transcription Factors - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Insulin-Like Growth Factor Binding Protein 1 - metabolism | Animals | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Cyclic AMP Response Element-Binding Protein - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Signal Transduction - physiology | Mice | PPAR alpha - metabolism | Endoplasmic Reticulum Stress - physiology | Insulin-Like Growth Factor Binding Protein 1 - genetics | Index Medicus | Gene Regulation | peroxisome proliferator-activated receptor (PPAR) | aryl hydrocarbon receptor (AhR) (AHR) | carbohydrate response element-binding protein (ChREBP) | endoplasmic reticulum stress (ER stress) | fibroblast growth factor (FGF) | glucose metabolism | energy metabolism | cAMP-responsive element-binding protein hepatocyte-specific (CREBH)
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 03/2007, Volume 292, Issue 3, pp. 788 - 801
Journal Article
Diabetes, ISSN 0012-1797, 09/2006, Volume 55, Issue 9, pp. 2502 - 2509
Journal Article
Journal Article