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Journal Article
The Journal of Physiology, ISSN 0022-3751, 03/2019, Volume 597, Issue 5, pp. 1227 - 1229
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2015, Volume 87, pp. 257 - 269
Abstract Familial hypertrophic cardiomyopathy (FHC) is characterized by severe abnormal cardiac muscle growth. The traditional view of disease progression in... 
Cardiovascular | Fluorescence spectroscopy | Hypertrophic cardiomyopathy | NMR spectroscopy | L29Q | Cardiac | Troponin C | CARDIAC & CARDIOVASCULAR SYSTEMS | PROTEIN | PHOSPHORYLATION | CROSS-LINKING | DILATED CARDIOMYOPATHY | CELL BIOLOGY | XPLOR-NIH | NMR | N-TERMINAL EXTENSION | CALCIUM | CA2+ BINDING | REGULATORY DOMAIN | Phosphorylation | Magnetic Resonance Spectroscopy | Signal Transduction | Calcium - metabolism | Cardiomyopathy, Hypertrophic, Familial - genetics | Cardiomyopathy, Hypertrophic, Familial - pathology | Humans | Cardiomyopathy, Hypertrophic, Familial - metabolism | Myocardium - pathology | Structure-Activity Relationship | Troponin C - metabolism | Myosins - genetics | Troponin C - genetics | Myocardial Contraction - genetics | Animals | Myocardium - metabolism | Myosins - metabolism | Protein Conformation | Troponin C - chemistry | Mutation | Circular Dichroism | Development and progression | Genetic aspects | Cardiomyopathy, Hypertrophic | Analysis | Myosin | Protein binding | cTnI, cardiac troponin I | NOE, nuclear overhauser enhancement | sNTnC, N-terminal domain of skeletal TnC | cNTnC, N-terminal domain of cTnC | cTnT, cardiac troponin T | PKC, protein kinase C | BR, bifunctional rhodamine | cTnC, cardiac TnC | ScTnC, trout cTnC | FISS, fluorescence for in situ structure | NMR, nuclear magnetic resonance | TnC, troponin C | NOESY, NOE spectroscopy | PKA, protein kinase A | HCM, hypertrophic cardiomyopathy | CD, circular dichroism | RMSD, root-mean-square deviation | FHC, familial hypertrophic cardiomyopathy
Journal Article
Journal Article
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 08/2018, Volume 122, Issue 32, pp. 7874 - 7883
Troponin C (TnC) facilitates muscle contraction through calcium-binding within its N-terminal region (NTnC). As previously observed using molecular dynamics... 
SKELETAL-MUSCLE | HYPERTROPHIC CARDIOMYOPATHY | CONTRACTILE PROPERTIES | HUMAN CARDIAC TROPONIN | THIN FILAMENT | CHEMISTRY, PHYSICAL | CALCIUM-BINDING | DILATED CARDIOMYOPATHY | REGULATORY DOMAIN | I MUTATION | FUNCTIONAL CONSEQUENCES
Journal Article
Cardiovascular Research, ISSN 0008-6363, 3/2008, Volume 77, Issue 4, pp. 619 - 626
Controversy abounds in the cardiac muscle literature over the rate-limiting steps of cardiac muscle contraction and relaxation. However, the idea of a single... 
Troponin | Muscle | Calcium | Cardiac | Myosin | CROSS-BRIDGE ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | calcium | myosin | MYOSIN HEAVY-CHAIN | I PHOSPHORYLATION | STRUCTURAL TRANSITION | HYPERTROPHIC CARDIOMYOPATHY | troponin | muscle | RELAXATION KINETICS | CALCIUM-BINDING | FORCE DEVELOPMENT | REGULATORY DOMAIN | cardiac | THIN-FILAMENT
Journal Article