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Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 39, pp. 15290 - 15303
Glucose is a critical nutrient for cell proliferation. However, the molecular pathways that regulate glucose metabolism are still elusive. We discovered that... 
CANCER-CELLS | serine | proliferation | TUMOR PROGRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PYRUVATE-KINASE M2 | METHYLTRANSFERASE 1 CARM1 | CELL-PROLIFERATION | protein methylation | GLUCOSE-METABOLISM | CARM1 | pyruvate kinase | AEROBIC GLYCOLYSIS | ARGININE METHYLATION | LACTATE METABOLISM | ONE-CARBON METABOLISM | metabolic regulation | Metabolism
Journal Article
Pathology International, ISSN 1320-5463, 01/2020, Volume 70, Issue 1, pp. 12 - 20
This study was to investigate the expression of coactivator‐associated arginine methyltransferase 1 (CARM1) and miR‐16‐5p in cervical cancer (CC), and explore... 
cervical cancer | CARM1 | miR‐16‐5p | radiosensitivity
Journal Article
Oncotarget, ISSN 1949-2553, 06/2019, Volume 10, Issue 38, p. 3709
Coactivator associated arginine methyltransferase 1 (CARM1) has been functionally implicated in maintenance of pluripotency, cellular differentiation and... 
Journal Article
Cell Reports, ISSN 2211-1247, 01/2019, Volume 26, Issue 2, pp. 302 - 312.e4
The coactivator-associated arginine methyltransferase CARM1 catalyzes the methylation of histone H3 arginine 17/26 (H3R17/26me) and non-histone proteins at... 
histone methylation | embryo development | H3R17 | Yap1 signaling | base editing | CARM1 | STEM-CELLS | DEFECTS | DNA METHYLATION | ARGININE METHYLTRANSFERASE CARM1 | REGENERATION | PLURIPOTENCY | EXPRESSION | GENOMIC DNA | H3K27ME3 | PLASTICITY | CELL BIOLOGY
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2019, Volume 62, Issue 11, pp. 5414 - 5433
PRMT4 is a type I protein arginine methyltransferase and plays important roles in various cellular processes. Overexpression of PRMT4 has been found to be... 
ANDROGEN RECEPTOR | COACTIVATOR | METHYLATION | CHEMISTRY, MEDICINAL | HISTONE H3 | CARM1 | TRANSCRIPTION | EXPRESSION | DISCOVERY
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 10/2018, Volume 430, Issue 21, pp. 4168 - 4182
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 08/2016, Volume 16, Issue 1, p. 34
Alterations in protein post-translational modification (PTM) are recognized hallmarks of diseases. These modifications potentially provide a unique source of... 
PRMT5 | SDMA | arginine methylation | CARM1 | HLA class I | ADMA | EThcD
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2019, Volume 512, Issue 1, pp. 34 - 40
The laryngeal squamous cell carcinoma (LSCC) represents a malignant cancer and contributes largely to head and neck tumorigenesis. The molecular mechanisms for... 
ST7-AS1 | lncRNA | Sox-2 | Laryngeal squamous cell carcinoma | CARM1 | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | IncRNA | CANCER
Journal Article
Autophagy, ISSN 1554-8627, 05/2019, Volume 15, Issue 5, pp. 913 - 914
Cellular adaption to nutrient stress is exquisitely regulated, and its dysregulation could underlie human diseases including neurodegeneration. C9orf72 is... 
autophagy | CARM1 | FTD | lipid metabolism | ALS | fatty acid | lysosome | C9orf72 | NOX2 | CELL BIOLOGY
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2019, Volume 520, Issue 3, pp. 645 - 650
Myocardial infarction due to coronary artery occlusion leads to adverse cardiac remodeling and heart failure. Apoptotic loss of cardiomyocytes near the... 
Myocardial infarction | PRMT4 | Apoptosis | BIOPHYSICS | CARM1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | Medical colleges | Arginine | Cardiology | Transferases | Heart attack
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2017, Volume 67, Issue 5, pp. 733 - 743.e4
Nuclear receptors recruit multiple coactivators sequentially to activate transcription. This “ordered” recruitment allows different coactivator activities to... 
p300 | sequential recruitment | histone modification | estrogen receptor | CARM1 | cryo-EM structure | SRC-3 | coactivator | METHYLATION | COMPLEX | ACTIVATION | HISTONE H3 | ARGININE METHYLTRANSFERASE CARM1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | TRANSCRIPTION | GENE-EXPRESSION | PROTEIN METHYLTRANSFERASE | ESTROGEN-RECEPTOR | CELL BIOLOGY | Histones - chemistry | Humans | Multiprotein Complexes | Transcriptional Activation | E1A-Associated p300 Protein - genetics | E1A-Associated p300 Protein - metabolism | Structure-Activity Relationship | Neoplasm Proteins - metabolism | CARD Signaling Adaptor Proteins - genetics | DNA-Binding Proteins - metabolism | CARD Signaling Adaptor Proteins - metabolism | Nuclear Receptor Coactivator 3 - chemistry | Transfection | MCF-7 Cells | Time Factors | HEK293 Cells | Estrogen Receptor alpha - metabolism | Transcription, Genetic | Protein Interaction Domains and Motifs | Acetylation | Neoplasm Proteins - genetics | Binding Sites | Guanylate Cyclase - chemistry | Promoter Regions, Genetic | Estrogen Receptor alpha - chemistry | E1A-Associated p300 Protein - chemistry | Models, Molecular | Guanylate Cyclase - metabolism | Nuclear Receptor Coactivator 3 - genetics | DNA-Binding Proteins - genetics | Cryoelectron Microscopy | Estrogen Receptor alpha - genetics | Nuclear Receptor Coactivator 3 - metabolism | CARD Signaling Adaptor Proteins - chemistry | Protein Binding | Guanylate Cyclase - genetics | Transcription Factors | HeLa Cells | Histones - metabolism | Methylation | Analysis | Estrogen | Medical colleges | Molecular biology | Transferases
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 11/2019, Volume 29, Issue 22, p. 126728
One of the regulatory mechanisms of epigenetic gene expression is the post-translational methylation of arginine residues, which is catalyzed by protein... 
Epigenetics | Asymmetric dimethylarginine | Enzyme assay | CARM1 | Fluorescent probe | COACTIVATOR | METHYLATION | CHEMISTRY, MEDICINAL | TRANSCRIPTION | VALIDATION | CHEMISTRY, ORGANIC | RECEPTOR
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2011, Volume 436, Issue 2, pp. 331 - 339
Journal Article