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Genes and Development, ISSN 0890-9369, 05/2011, Volume 25, Issue 10, pp. 1041 - 1051
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 29, pp. 25655 - 25662
Journal Article
Cell Reports, ISSN 2211-1247, 02/2018, Volume 22, Issue 6, pp. 1365 - 1373
Lysine succinylation was recently identified as a post-translational modification in cells. However, the molecular mechanism underlying lysine succinylation... 
carnitine palmitoyltransferase 1A | CPT1A | signal transduction | lysine succinylation | succinyl-CoA | metabolism | post-translational modification | lysine succinyltransferase | SUCCINYLATION | FATTY-ACID OXIDATION | MALONYL-COA | ACETYLATION | PHOSPHORYLATION | MITOCHONDRIA | MUTATION | IMPAIRS | STRUCTURAL MODEL | IDENTIFICATION | CELL BIOLOGY
Journal Article
by Qu, Q and Zeng, F and Liu, X and Wang, Q.J and Deng, F
Cell Death and Disease, ISSN 2041-4889, 2016, Volume 7, Issue 5, pp. e2226 - e2226
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 01/2016, Volume 1861, Issue 1, pp. 34 - 40
Canitine palmitoyltransferases (CPT), located both in the outer (CPT I) and inner membrane (CPT II) of mitochondria, are the key players for an efficient... 
DECARBOXYLASE | CPT-II | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | HUMAN SKELETAL-MUSCLE | DEFICIENCY | CELL BIOLOGY | ENZYME | BIOPHYSICS | DEACETYLATION | CARNITINE PALMITOYLTRANSFERASE | EXPRESSION
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2014, Volume 448, Issue 2, pp. 175 - 181
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 03/2018, Volume 25, Issue 4, pp. 733 - 746
Cellular senescence is a fundamental biological process that has profound implications in cancer development and therapeutics, but the underlying mechanisms... 
HOMEOSTASIS | SECRETORY PHENOTYPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYSFUNCTION | STRESS | TUMOR-GROWTH | DNA MUTATIONS | REVEALS | CELL BIOLOGY | Metabolomics | Senescence | Cell survival | mRNA | Tumor cell lines | Palmitoyltransferase | Metabolism | Drug development | Fatty acids | Carnitine palmitoyltransferase | Carnitine | Mitochondria | Pancreatic carcinoma | Xenografts | Biomarkers | Tumorigenesis | Oxidation | Cancer
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 45, pp. 18443 - 18456
Cardiac hypertrophy is closely linked to impaired fatty acid oxidation, but the molecular basis of this link is unclear. Here, we investigated the loss of an... 
MORTALITY | TARGET | PATHOLOGICAL HYPERTROPHY | cardiac metabolism | BIOCHEMISTRY & MOLECULAR BIOLOGY | mammalian target of rapamycin (mTOR) | HDAC INHIBITION | FAILURE | LEFT-VENTRICULAR HYPERTROPHY | DIASTOLIC DYSFUNCTION | acetylation | METABOLISM | FATTY-ACID OXIDATION | fatty acid oxidation | cardiac hypertrophy | CORONARY-HEART-DISEASE | Carnitine O-Palmitoyltransferase - genetics | Mitochondria, Heart - metabolism | Mitochondria, Heart - pathology | Atrial Remodeling - drug effects | Cardiomegaly - etiology | Male | Metabolism, Inborn Errors - therapy | Mitochondria, Heart - drug effects | Protein Processing, Post-Translational - drug effects | Carnitine O-Palmitoyltransferase - metabolism | Myocardium - metabolism | Carnitine O-Palmitoyltransferase - deficiency | Drug Resistance | Heart - physiopathology | Sirolimus - therapeutic use | Specific Pathogen-Free Organisms | Diet, Ketogenic | Metabolism, Inborn Errors - metabolism | Mice, Transgenic | Myocardium - pathology | Mechanistic Target of Rapamycin Complex 1 - antagonists & inhibitors | Enzyme Activation - drug effects | Mechanistic Target of Rapamycin Complex 1 - metabolism | Mice, Knockout | Acetylation - drug effects | Myocardium - enzymology | Animals | Cardiomegaly - prevention & control | Protein Kinase Inhibitors - therapeutic use | Survival Analysis | Heart - drug effects | Histone Deacetylase Inhibitors - therapeutic use | Metabolism, Inborn Errors - pathology | Metabolism, Inborn Errors - physiopathology | Crosses, Genetic | Lipids
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0159399
The discovery of active brown adipose tissue (BAT) in adult humans and the fact that it is reduced in obese and diabetic patients have put a spotlight on this... 
BETA-OXIDATION | METABOLIC SYNDROME | ADIPOSE-TISSUE ACTIVITY | FATTY-ACID OXIDATION | MALONYL-COA | MULTIDISCIPLINARY SCIENCES | UNCOUPLING PROTEIN-1 | GENE-EXPRESSION | ADULT HUMANS | MUSCLE-CELLS | INDUCED INSULIN-RESISTANCE | Adipocytes, Brown - pathology | Thermogenesis - genetics | Carnitine O-Palmitoyltransferase - genetics | Lipids - genetics | Uncoupling Protein 1 - genetics | Adipocytes, Brown - metabolism | Humans | Rats | Mitochondria - metabolism | Mitochondria - pathology | Obesity - genetics | Uncoupling Protein 1 - biosynthesis | Obesity - metabolism | Obesity - pathology | Gene Expression Regulation, Enzymologic | Lipolysis - genetics | Cell Differentiation - genetics | Animals | Lipid Metabolism - genetics | Energy Metabolism - genetics | Carnitine O-Palmitoyltransferase - biosynthesis | Obesity | Fat cells | Research | Health aspects | Analysis | Lipolysis | Adipose tissue | Disorders | Lipids | Biochemistry | Adipocytes | Palmitic acid | Proteins | Mitochondria | Rodents | Tomography | Physiology | Oxidation | Bioindicators | Adipose tissue (brown) | Diabetes mellitus | Energy expenditure | Inflammation | Metabolism | Gene expression | Palmitoyltransferase | Fatty acids | Carnitine palmitoyltransferase | Carnitine | Burning | Thermogenesis | Incineration | Insulin resistance | Diabetes | Respiration | Metabolic disorders | Obesitat | Adipose tissues | Carnitina palmitoïl-transferasa 1 | Carnitine palmitoyltransferase I | Teixit adipós
Journal Article