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BioEssays, ISSN 0265-9247, 01/2019, Volume 41, Issue 1, p. e1800166
Proteoglycan 4 (PRG4), first identified in synovial fluid, is an extracellular matrix structural protein in the joint implicated in reducing shear at the... 
protease | lubricin | proteoglycan 4 | inflammation | glycosylation | post-translation modification | PRG4 | PATHWAYS | MECHANISM | SYNOVIOCYTE PROLIFERATION | SYNOVIAL-FLUID | BIOCHEMISTRY & MOLECULAR BIOLOGY | BOUNDARY LUBRICATION | PREVENTION | CARTILAGE | ZONE PROTEIN | BIOLOGY | EXPRESSION
Journal Article
The FEBS Journal, ISSN 1742-464X, 10/2010, Volume 277, Issue 19, pp. 3904 - 3923
The expression of proteoglycans (PGs), essential macromolecules of the tumor microenvironment, is markedly altered during malignant transformation and tumor... 
proteoglycans | lumican | decorin | syndecans | molecular targeting | perlecan | versican | cancer | serglycin | glypicans | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIGH SYNDECAN-1 EXPRESSION | BEHMEL OVERGROWTH SYNDROME | GROWTH-FACTOR RECEPTOR | BREAST-CANCER CELLS | STROMAL VERSICAN EXPRESSION | LEUCINE-RICH PROTEOGLYCANS | IN-VIVO | SQUAMOUS-CELL CARCINOMA | HEPARAN-SULFATE PROTEOGLYCANS | TUMOR-GROWTH | Decorin | Prognosis | Cartilage - pathology | Humans | Aggrecans - therapeutic use | Proteoglycans - drug effects | Lectins, C-Type - metabolism | Versicans - genetics | Neoplasms - genetics | Cell Division | Glioma - pathology | Neovascularization, Pathologic - physiopathology | Neoplasms - physiopathology | Extracellular Matrix Proteins - metabolism | Chondroitin Sulfate Proteoglycans - metabolism | Proteoglycans - metabolism | Aggrecans - metabolism | Disease Progression | Neoplasms - drug therapy | Nerve Tissue Proteins - metabolism | Proteoglycans - therapeutic use | Brevican | Proteoglycans - physiology | Agrin - physiology | Hyaluronic Acid - metabolism | Biomarkers | Inflammation - genetics | Glioma - physiopathology | Neoplasms - pathology | Versicans - therapeutic use | Proteoglycans - genetics | Proteases | Oncology, Experimental | Physiological aspects | Medical law | Development and progression | Research | Cancer | Gene expression | Pharmacology | Tumors | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICINE | MEDICIN
Journal Article
Journal Article
Journal of Orthopaedic Research, ISSN 0736-0266, 11/2018, Volume 36, Issue 11, pp. 2923 - 2931
ABSTRACT The objective of this study was to determine the effect of different sliding interface materials (counterface) on the cartilage lubricating ability of... 
glass | proteoglycan 4 | hyaluronan | boundary lubrication | cartilage | FRICTION | MOLECULAR-WEIGHT | MECHANISM | SYNOVIAL-FLUID | MODEL | CONTACT PRESSURES | ARTICULAR-CARTILAGE | SURFACE | ORTHOPEDICS | Hyaluronic acid
Journal Article
Journal of Orthopaedic Research, ISSN 0736-0266, 10/2019, Volume 37, Issue 10, pp. 2077 - 2088
ABSTRACT Proteoglycan 4 (PRG4) is a mucin‐like glycoprotein important for joint health. Mice lacking Prg4 demonstrate degeneration of the cartilage and altered... 
proteoglycan 4 | arthrosis | hyaluronan | osteoarthritis | cartilage | methylprednisolone | subchondral bone | KNEE | PREVENTION | RESTORATION | HYALURONIC-ACID | DEGENERATION | ARTICULAR-CARTILAGE | LUBRICIN TRIBOSUPPLEMENTATION | PARATHYROID-HORMONE | ORTHOPEDICS | Corticosteroids | Analysis | Mice | Porosity | Hyaluronic acid | Methylprednisolone | Osteoarthritis
Journal Article
Science Translational Medicine, ISSN 1946-6234, 03/2013, Volume 5, Issue 176, pp. 176 - 176ra34
Osteoarthritis (OA) is a common degenerative condition that afflicts more than 70% of the population between 55 and 77 years of age. Although its prevalence is... 
CHONDROCYTE HYPERTROPHY | MEDICINE, RESEARCH & EXPERIMENTAL | REGULATOR | DEPENDENT ADENOVIRAL VECTORS | GROWTH | LUBRICIN | GENE-THERAPY | DIFFERENTIATION | HISTOPATHOLOGY | CARTILAGE | DELIVERY | CELL BIOLOGY
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 2011, Volume 1812, Issue 12, pp. 1616 - 1629
Journal Article