X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1446) 1446
humans (1251) 1251
apoptosis (902) 902
casp8 and fadd-like apoptosis regulating protein - metabolism (650) 650
casp8 and fadd-like apoptosis regulating protein (607) 607
apoptosis - drug effects (539) 539
animals (538) 538
cell line, tumor (411) 411
intracellular signaling peptides and proteins (403) 403
casp8 and fadd-like apoptosis regulating protein - genetics (396) 396
mice (377) 377
c-flip (359) 359
cell biology (351) 351
oncology (348) 348
caspases - metabolism (328) 328
biochemistry & molecular biology (325) 325
nf-kappa-b (313) 313
activation (291) 291
signal transduction (276) 276
apoptosis - physiology (271) 271
female (270) 270
death (266) 266
caspase 8 (259) 259
down-regulation (254) 254
male (235) 235
expression (228) 228
carrier proteins - metabolism (214) 214
fas receptor - metabolism (210) 210
caspase 8 - metabolism (209) 209
trail (207) 207
mediated apoptosis (190) 190
cells, cultured (188) 188
nf-kappa b - metabolism (186) 186
cancer (181) 181
proteins (176) 176
up-regulation (176) 176
tnf-related apoptosis-inducing ligand - pharmacology (169) 169
caspase-8 (163) 163
immunology (161) 161
abridged index medicus (160) 160
antineoplastic agents - pharmacology (156) 156
caspase 9 (154) 154
tumor necrosis factor-alpha - pharmacology (152) 152
flip (146) 146
tumor cells, cultured (145) 145
tnf-related apoptosis-inducing ligand (143) 143
blotting, western (140) 140
intracellular signaling peptides and proteins - metabolism (139) 139
cell line (135) 135
trail-induced apoptosis (135) 135
apoptosis - genetics (134) 134
fas (129) 129
carrier proteins - genetics (128) 128
proto-oncogene proteins c-bcl-2 - metabolism (126) 126
signaling complex (125) 125
apoptosis regulatory proteins (123) 123
enzyme activation (123) 123
fas receptor - physiology (121) 121
signal transduction - drug effects (121) 121
transfection (121) 121
protein (119) 119
receptor (116) 116
in-vivo (115) 115
gene expression (113) 113
caspase inhibitors (110) 110
flow cytometry (110) 110
reverse transcriptase polymerase chain reaction (108) 108
fas ligand protein (107) 107
middle aged (107) 107
death receptors (106) 106
article (102) 102
cell-death (101) 101
fas-mediated apoptosis (101) 101
resistance (100) 100
caspase-8 activation (99) 99
tumor-necrosis-factor (99) 99
tnf-related apoptosis-inducing ligand - metabolism (97) 97
membrane glycoproteins - metabolism (96) 96
research (95) 95
tumor necrosis factor-alpha - metabolism (95) 95
drug synergism (94) 94
inhibition (93) 93
induced apoptosis (92) 92
adult (90) 90
immunohistochemistry (89) 89
ligand (89) 89
receptors, tnf-related apoptosis-inducing ligand - metabolism (89) 89
aged (88) 88
cell death (87) 87
hematology (87) 87
rna, messenger - metabolism (87) 87
apoptosis - immunology (86) 86
cell survival - drug effects (86) 86
phosphorylation (86) 86
mice, inbred c57bl (85) 85
casp8 and fadd-like apoptosis regulating protein - biosynthesis (84) 84
caspase 3 (84) 84
cells (84) 84
carrier proteins - physiology (83) 83
drug resistance, neoplasm (80) 80
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1479) 1479
Chinese (15) 15
Japanese (3) 3
German (2) 2
French (1) 1
Polish (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Medicine, ISSN 1078-8956, 04/2017, Volume 23, Issue 4, pp. 439 - 449
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2011, Volume 43, Issue 3, pp. 432 - 448
A better understanding of the mechanisms through which anticancer drugs exert their effects is essential to improve combination therapies. While studying how... 
CASPASE INHIBITORS | TUMOR-NECROSIS-FACTOR | LIGASE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | ALPHA-DEPENDENT APOPTOSIS | TRAIL-INDUCED APOPTOSIS | TNF-ALPHA | CHEMOTHERAPEUTIC DRUGS | NF-KAPPA-B | CELL-DEATH | CELL BIOLOGY | CASP8 and FADD-Like Apoptosis Regulating Protein - physiology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Caspase 8 - metabolism | Nuclear Pore Complex Proteins - chemistry | Caspase 8 - chemistry | Inhibitor of Apoptosis Proteins - physiology | Nuclear Pore Complex Proteins - physiology | Antineoplastic Agents - pharmacology | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Fas-Associated Death Domain Protein - physiology | RNA-Binding Proteins - physiology | Signal Transduction | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Nuclear Pore Complex Proteins - metabolism | RNA-Binding Proteins - chemistry | Fas-Associated Death Domain Protein - metabolism | Etoposide - pharmacology | Mitochondria - metabolism | Caspase 8 - physiology | Fas-Associated Death Domain Protein - chemistry | Cell Line, Tumor | Ligands | Apoptosis - physiology | DNA Damage | Enzyme Activation | RNA-Binding Proteins - metabolism | Ubiquitin | Green design | Oncology, Experimental | Internet service providers | Research | Sustainable development | Cancer | Index Medicus
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2009, Volume 11, Issue 11, pp. 1355 - 1362
Journal Article
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/2009, Volume 187, Issue 7, pp. 1037 - 1054
Journal Article
Molecular Cell, ISSN 1097-2765, 2005, Volume 20, Issue 6, pp. 939 - 949
The death-inducing signaling complex (DISC) comprising Fas, Fas-associated death domain (FADD), and caspase-8/10 is assembled via homotypic associations... 
RECEPTOR SIGNALS | APOPTOSIS | INDUCED-PROXIMITY MODEL | BIOCHEMISTRY & MOLECULAR BIOLOGY | NMR STRUCTURE | DEATH-EFFECTOR DOMAIN | CASPASE ACTIVATION | CONTAINING PROTEIN | SIGNALING COMPLEX DISC | CELL-DEATH | PYRIN DOMAIN | CELL BIOLOGY | Caspase 8 | Humans | Multiprotein Complexes | Molecular Sequence Data | Crystallography, X-Ray | Intracellular Signaling Peptides and Proteins - metabolism | fas Receptor - metabolism | Viral Proteins - metabolism | Death Domain Receptor Signaling Adaptor Proteins | Caspases - metabolism | Molluscum contagiosum virus - genetics | Caspase 10 | fas Receptor - genetics | Intracellular Signaling Peptides and Proteins - genetics | Amino Acid Sequence | Caspases - genetics | Viral Proteins - chemistry | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Models, Molecular | Viral Proteins - genetics | Fas-Associated Death Domain Protein | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - chemistry | Sequence Alignment | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Adaptor Proteins, Signal Transducing - genetics | Molluscum contagiosum virus - chemistry | Protein Conformation | CASP8 and FADD-Like Apoptosis Regulating Protein | Apoptosis - physiology | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Proteins | Oligomers | Structure | Crystals | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2016, Volume 64, Issue 2, pp. 236 - 250
Caspase-8 activation can be triggered by death receptor-mediated formation of the death-inducing signaling complex (DISC) and by the inflammasome adaptor ASC.... 
caspase-8 | DED | MC159 | cFLIP | DISC | Fas | death domain | FADD | vFLIP | filament | APOPTOSIS | ACTIVATION | IMMUNE-SYSTEM | INHIBITION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | UNIFIED MODEL | EFFECTOR DOMAIN | CELL-DEATH | CELL BIOLOGY | Death Domain Receptor Signaling Adaptor Proteins - chemistry | Apoptosis - drug effects | Cytoskeletal Proteins - genetics | Humans | Caspase 8 - metabolism | Caspase 8 - chemistry | CASP8 and FADD-Like Apoptosis Regulating Protein - chemistry | Death Domain Receptor Signaling Adaptor Proteins - genetics | Recombinant Fusion Proteins - metabolism | Viral Proteins - metabolism | Caspase 8 - genetics | Transfection | Cytoskeletal Proteins - metabolism | Protein Interaction Domains and Motifs | Binding Sites | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Death Effector Domain | Fas-Associated Death Domain Protein - genetics | Amino Acid Sequence | Protein Conformation, alpha-Helical | Gene Expression | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Jurkat Cells | Viral Proteins - chemistry | Fas-Associated Death Domain Protein - metabolism | Viral Proteins - genetics | fas Receptor - pharmacology | Cytoskeletal Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Plasmids - metabolism | Fas-Associated Death Domain Protein - chemistry | Cryoelectron Microscopy | Sequence Homology, Amino Acid | Sequence Alignment | Protein Conformation, beta-Strand | CARD Signaling Adaptor Proteins | Plasmids - chemistry | Protein Binding | Recombinant Fusion Proteins - genetics | Death Domain Receptor Signaling Adaptor Proteins - metabolism | Autoimmunity | Medical colleges | Skin diseases | Molecular biology | Analysis | Index Medicus
Journal Article