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Journal of Immunology, ISSN 0022-1767, 05/2005, Volume 174, Issue 9, pp. 5270 - 5278
Journal Article
Immunity, ISSN 1074-7613, 02/2012, Volume 36, Issue 2, pp. 215 - 227
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 131, Issue 4, pp. 669 - 681
Inhibitor of apoptosis (IAP) proteins are antiapoptotic regulators that block cell death in response to diverse stimuli. They are expressed at elevated levels... 
CELLBIO | HUMDISEASE | SIGNALING | MULTIPLE-MYELOMA | CASPASE-8 ACTIVATION | NECROSIS-FACTOR RECEPTOR | ML-IAP | PROTEIN | STRUCTURAL BASIS | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SMAC | INHIBITOR | SIGNALING COMPLEX | CELL BIOLOGY
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 05/2016, Volume 117, Issue 5, pp. 1078 - 1091
ABSTRACT It is well known that tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL)‐induced apoptosis can be initially triggered by surface death... 
TRAIL‐INDUCED ER STRESS | CLEAVAGE OF BAP31 | PERK‐eIF2α‐ATF4‐CHOP SIGNALS | TRAIL‐INDUCED CASPASE‐8 ACTIVATION | Trail-induced caspase-8 activation | Cleavage of BAP31 | PERK-eIF2α-ATF4-CHOP signals | Trail-induced er stress | TRAIL-INDUCED ER STRESS | PERK-eIF2α-ATF4-CHOP SIGNALS | TRAIL-INDUCED CASPASE-8 ACTIVATION | PROTEIN | INDUCED APOPTOSIS | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | CELL-DEATH | BAP31 | CELL BIOLOGY | PERK-eIF2 alpha-ATF4-CHOP SIGNALS | CYTOCHROME-C | COLORECTAL-CANCER | METABOLIC OXIDATIVE STRESS | Transcription Factor CHOP - genetics | Apoptosis - drug effects | eIF-2 Kinase - metabolism | Humans | Caspase 8 - metabolism | Cell Survival - genetics | Apoptosis - genetics | Endoplasmic Reticulum Stress - genetics | Caspase 8 - genetics | TNF-Related Apoptosis-Inducing Ligand - pharmacology | MCF-7 Cells | RNA Interference | Membrane Proteins - metabolism | Fibroblasts - metabolism | eIF-2 Kinase - genetics | Endoplasmic Reticulum Stress - drug effects | HCT116 Cells | Cells, Cultured | Signal Transduction - genetics | Enzyme Activation - drug effects | Blotting, Western | Mice, Knockout | HT29 Cells | Microscopy, Confocal | Animals | Signal Transduction - drug effects | Embryo, Mammalian - cytology | Cell Line, Tumor | Fibroblasts - cytology | Transcription Factor CHOP - metabolism | TNF-Related Apoptosis-Inducing Ligand - genetics | Cellular signal transduction | Stress (Physiology) | Colorectal cancer | Protein binding
Journal Article
Immunity, ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 649 - 659
Intestinal epithelial cells (IECs) form a critical barrier against pathogen invasion. By generation of mice in which inflammasome expression is restricted to... 
Caspase-8 | ASC | intestinal epithelial cell | inflammasome | extrusion | Nlrc4 | expulsion | Naip | Caspase-1 | BACTERIAL PATHOGENS | IN-VIVO | HOST-DEFENSE | SALMONELLA | NLRP3 | MICE | IL-1-BETA | NLRC4 | IMMUNOLOGY | NF-KAPPA-B | AUTOINFLAMMATION | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Inflammasomes - metabolism | Caspase 8 - metabolism | Eicosanoids - secretion | Caspase 1 - metabolism | Salmonella Infections - metabolism | Caspase 8 - genetics | Apoptosis Regulatory Proteins - genetics | Calcium-Binding Proteins - metabolism | Salmonella typhimurium - physiology | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Mice, Transgenic | Intestinal Mucosa - microbiology | Neuronal Apoptosis-Inhibitory Protein - metabolism | Inflammasomes - genetics | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Microscopy, Confocal | Animals | Caspase 1 - genetics | Epithelial Cells - microbiology | Interleukin-18 - secretion | Salmonella Infections - microbiology | Enzyme Activation | Calcium-Binding Proteins - genetics | Intestinal Mucosa - pathology | Diarrhea | Medicine, Experimental | Medical research | Muscle proteins | Analysis | Cells | Salmonella | Bacterial infections | Cytokines | Lipids | Infections | Inflammation | Small intestine | Studies | Immunology | Organoids | Rodents | Bone marrow | Ligands | Mutation | Apoptosis
Journal Article
Nature Communications, ISSN 2041-1723, 02/2015, Volume 6, Issue 1, p. 6282
RIPK3 and its substrate MLKL are essential for necroptosis, a lytic cell death proposed to cause inflammation via the release of intracellular molecules.... 
RHEUMATOID-ARTHRITIS | NECROPTOSIS | MULTIDISCIPLINARY SCIENCES | DOMAIN-LIKE PROTEIN | MIXED LINEAGE KINASE | PROGRAMMED NECROSIS | DEPENDENT APOPTOSIS | CASPASE-8 | TNF-ALPHA | NF-KAPPA-B | INNATE IMMUNITY
Journal Article