X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2705) 2705
Publication (303) 303
Book Chapter (37) 37
Book Review (31) 31
Dissertation (17) 17
Conference Proceeding (8) 8
Data Set (2) 2
Government Document (2) 2
Newspaper Article (1) 1
Streaming Video (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
cathepsin k (1513) 1513
humans (1298) 1298
index medicus (1293) 1293
animals (1178) 1178
cathepsin-k (713) 713
mice (682) 682
cathepsins (586) 586
female (584) 584
osteoporosis (530) 530
male (516) 516
expression (468) 468
osteoclasts (451) 451
bone resorption (429) 429
biochemistry & molecular biology (423) 423
cathepsin k - metabolism (355) 355
osteoclast (330) 330
cathepsins - metabolism (321) 321
osteoclasts - metabolism (313) 313
bone (309) 309
cell biology (308) 308
bone-resorption (303) 303
endocrinology & metabolism (294) 294
osteoclasts - drug effects (286) 286
gene expression (282) 282
analysis (272) 272
differentiation (271) 271
cells, cultured (261) 261
collagen (255) 255
rats (249) 249
osteoclasts - cytology (247) 247
osteoclastogenesis (237) 237
cathepsins - genetics (230) 230
middle aged (230) 230
in-vitro (228) 228
pharmacology & pharmacy (221) 221
immunohistochemistry (219) 219
cells (218) 218
tartrate-resistant acid phosphatase (217) 217
cathepsin k - antagonists & inhibitors (212) 212
resorption (212) 212
cathepsins - antagonists & inhibitors (208) 208
proteins (202) 202
activation (197) 197
chemistry, medicinal (197) 197
cathepsin k - genetics (196) 196
postmenopausal women (189) 189
acid phosphatase (183) 183
adult (182) 182
aged (179) 179
orthopedics (178) 178
macrophages (175) 175
article (169) 169
biocompatibility (167) 167
inflammation (167) 167
cysteine (163) 163
mice, inbred c57bl (159) 159
research (159) 159
cell differentiation - drug effects (155) 155
enzymes (155) 155
bones (154) 154
medicine, research & experimental (150) 150
pycnodysostosis (150) 150
rheumatology (150) 150
molecular-cloning (149) 149
matrix metalloproteinases (148) 148
rankl (147) 147
cell differentiation (143) 143
pathology (143) 143
trance protein (142) 142
research article (140) 140
chemistry, organic (136) 136
osteoporosis - drug therapy (135) 135
bone resorption - metabolism (134) 134
medicine (133) 133
oncology (133) 133
gene-expression (132) 132
cancer (131) 131
osteoblasts (131) 131
physiological aspects (131) 131
osteoclasts - pathology (130) 130
acid phosphatase - metabolism (128) 128
inhibitors (128) 128
cysteine proteinase inhibitors - pharmacology (127) 127
inhibition (127) 127
rank ligand - metabolism (127) 127
structure-activity relationship (127) 127
biomedical materials (126) 126
isoenzymes - metabolism (126) 126
cell line (125) 125
signal transduction (125) 125
osteoprotegerin (122) 122
rna, messenger - metabolism (120) 120
bone marrow (118) 118
cathepsin l (118) 118
receptor activator (118) 118
cysteine protease (117) 117
dentistry (117) 117
dentistry, oral surgery & medicine (117) 117
disease (117) 117
disease models, animal (117) 117
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2647) 2647
Japanese (27) 27
German (22) 22
Chinese (21) 21
Spanish (12) 12
French (10) 10
Korean (5) 5
Russian (5) 5
Polish (2) 2
Croatian (1) 1
Czech (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2019, Volume 34, Issue 4, pp. 777 - 778
Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 04/2019, Volume 27, pp. S20 - S20
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 11/2011, Volume 133, Issue 43, pp. 17164 - 17167
A novel method for caging protease inhibitors is described. The complex [Ru-II(bpy)(2)(1)(2)](PF6)(2) (2) was prepared from the nitrile-based peptidomimetic... 
ROLES | CATHEPSIN-K | COVALENT BINDING | DNA | COMPLEXES | PHOTODELIVERY | TARGETS | CANCER | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
DEVELOPMENTAL CELL, ISSN 1534-5807, 11/2011, Volume 21, Issue 5, pp. 966 - 974
Osteoclasts resorb bone via the ruffled border, whose complex folds are generated by secretory lysosome fusion with bone-apposed plasma membrane. Lysosomal... 
PATHWAY | CATHEPSIN-K | MEMBRANE | RUFFLED BORDER | MICE | DEVELOPMENTAL BIOLOGY | BETA-CELL MASS | PAGETS-DISEASE | UNCONVENTIONAL SECRETION | RESORBING OSTEOCLASTS | GENE ATG16L1 | CELL BIOLOGY
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 23, pp. 10665 - 10699
Ongoing interest in the discovery of selective JAK3 inhibitors led us to design novel covalent inhibitors that engage the JAK3 residue Cys909 by cyanamide, a... 
DESIGN | POTENT | ACTIVATION | CHEMISTRY, MEDICINAL | CATHEPSIN-K | STATS | SELECTIVITY | DERIVATIVES | DISCOVERY | PREDICTION | FAMILY
Journal Article
Organic Process Research and Development, ISSN 1083-6160, 02/2016, Volume 20, Issue 2, pp. 140 - 177
This review showcases various coupling reagents which have been implemented specifically for large-scale amide synthesis via the condensation of an acid and... 
PILOT-PLANT-SCALE | LEUKOCYTE ELASTASE INHIBITOR | CONVERTING-ENZYME-INHIBITOR | PRACTICAL ASYMMETRIC-SYNTHESIS | RESEARCH-AND-DEVELOPMENT | NONACTIVATED CARBOXYLIC-ACIDS | CHEMISTRY, ORGANIC | CATHEPSIN-K INHIBITOR | HYDROGENATION-BASED SYNTHESIS | HCV PROTEASE INHIBITOR | CHEMISTRY, APPLIED | COST-EFFECTIVE SYNTHESIS
Journal Article
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 11/2017, Volume 5, Issue 11, pp. 898 - 907
Osteoporosis is an enormous and growing public health problem. Once considered an inevitable consequence of ageing, it is now eminently preventable and... 
BONE-MINERAL DENSITY | TASK-FORCE | THERAPEUTIC TARGET | DISEASE | ENDOCRINOLOGY & METABOLISM | ESTROGEN | CATHEPSIN K | VERTEBRAL FRACTURE | OSTEOPROTEGERIN | POSTMENOPAUSAL WOMEN | HUMAN PARATHYROID-HORMONE
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2019, Volume 25, Issue 2, pp. 652 - 662
Purpose: Cabozantinib is a multitargeted tyrosine kinase inhibitor that demonstrated remarkable responses on bone scan in metastatic prostate cancer.... 
PHASE-III TRIAL | MATRIX | PREDNISONE | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | CATHEPSIN-K | FDG | INHIBITOR | EXPRESSION | DOCETAXEL | CHEMOTHERAPY
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2018, Volume 33, Issue 1, pp. 890 - 904
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 05/2016, Volume 779, pp. 8 - 21
Since the mid-1980s, postmenopausal osteoporosis (PMO) has been considered a serious public health concern because of the associated fractures. Pharmacological... 
Bisphosphonate | Cathepsin K | Romosozumab | Denosumab | Long-term-Treatment | Postmenopausal Osteoporosis
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 10, p. e0142116
S6_File.xls A B C D E F G H I J K L M N 1 EntrezID GeneSymbol GeneName AffymetrixID Family Subfamily geneindex FC:(class1/class2) pfp Pvalue 2 1075 CTSC... 
Cathepsin K | Gene expression | Glioblastoma | Apoptosis
Journal Article
Organic Letters, ISSN 1523-7060, 12/2016, Volume 18, Issue 23, pp. 5994 - 5997
A simple and efficient method for converting methyl sulfones to sulfinic acids is described. The process involves alkylation with a benzylic halide, followed... 
MILD | DIARYL SULFONES | ODANACATIB | CATHEPSIN-K | ALKENE SYNTHESIS | CHEMISTRY, ORGANIC | ARYL SULFONES | SULFONAMIDES | INHIBITOR | SALTS | DISCOVERY
Journal Article
Journal of Advanced Pharmacy Education and Research, 04/2017, Volume 7, Issue 2, pp. 168 - 169
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 10/2019, Volume 93, pp. 153 - 160
Cathepsins are the best-known group of proteases in lysosomes, playing a significant role in immune responses. Cathepsin K ( ) is abundantly and selectively... 
Vibrio anguillarum | Cathepsin K | Turbot | Streptococcus iniae | Microbial ligand binding ability
Journal Article
Chemical Society reviews, ISSN 0306-0012, 06/2018, Volume 47, Issue 11, pp. 3816 - 3830
Covalent inhibition is a rapidly growing discipline within drug discovery. Many historical covalent inhibitors were discovered by serendipity, with such a... 
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 09/2019, Volume 858, p. 172382
Breast cancer is one of the main diagnosis cancers annually worldwide. It is difficult to thorough cure due to drug resistance and the high possibility of... 
Testosterone | Bcl-xL | Breast cancer | Cathepsin K | SM934 | PROSTATE | BCL-2 | GENE | TUMOR | PHARMACOLOGY & PHARMACY | MODEL
Journal Article
Organic Process Research and Development, ISSN 1083-6160, 11/2015, Volume 19, Issue 11, pp. 1731 - 1746
Asymmetric phase transfer catalysis has been recognized as an approach that is greener and more sustainable than synthetic alternatives and has evolved into... 
PRACTICAL SYNTHESIS | ENANTIOSELECTIVE SYNTHESIS | CATHEPSIN-K | VANIPREVIR MK-7009 | QUATERNARY STEREOCENTERS | ALLYLIC ALKYLATION | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | CHEMISTRY, APPLIED | VIRUS NS3/4A PROTEASE | INHIBITOR | ESTROGEN-RECEPTOR
Journal Article
CLINICAL SCIENCE, ISSN 0143-5221, 08/2019, Volume 133, Issue 16, pp. 1813 - 1824
Purpose: To shed light on the idea that mesenchymal stem/stromal cells (MSCs) recruited in synovium (SM) (i.e.Synovium-Derived Stromal Cells, SDSCs) could be... 
PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | SITE | THERAPY | FLUID | CATHEPSIN-K | DIFFERENTIATION | EXPRESSION | MESENCHYMAL STEM-CELLS | PCR | CARTILAGE | Index Medicus
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.