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Journal of Neuroscience, ISSN 0270-6474, 04/2007, Volume 27, Issue 14, pp. 3663 - 3676
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 10/2012, Volume 287, Issue 44, pp. 36944 - 36967
The alpha-hemoglobin-derived dodecapeptide RVD-hemopressin (RVDPVNFKLLSH) has been proposed to be an endogenous agonist for the cannabinoid receptor type 1... 
SPECTROMETRY-BASED QUANTIFICATION | HEMOGLOBIN-DERIVED PEPTIDES | SIGNAL-TRANSDUCTION | MOUSE-BRAIN | INHIBITION | PHARMACOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANNABINOID CB1 | ADENYLATE-CYCLASE | BINDING | AGONIST | Cannabinoid Receptor Modulators - metabolism | Epitope Mapping | Cannabinoid Receptor Modulators - blood | Allosteric Regulation | Humans | Molecular Sequence Data | Male | Brain - metabolism | Tandem Mass Spectrometry | Cyclohexanols - metabolism | Receptor, Cannabinoid, CB1 - agonists | Peptide Fragments - immunology | Peptide Fragments - blood | Cannabinoid Receptor Modulators - chemical synthesis | Female | Hemoglobins - biosynthesis | CHO Cells | Binding, Competitive | Amino Acid Sequence | Cricetinae | Peptide Fragments - metabolism | Signal Transduction | Mice, Inbred C57BL | Hemoglobins - immunology | Hemoglobins - metabolism | Rats | Mice, Inbred NZB | Peptide Fragments - biosynthesis | Protein Transport | Antibodies, Monoclonal, Murine-Derived - biosynthesis | Hemoglobins - chemical synthesis | Peptide Fragments - chemical synthesis | Receptor, Cannabinoid, CB1 - metabolism | Hemoglobins - chemistry | Animals | HL-60 Cells | Protein Binding | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Cannabinoid Receptor Modulators - immunology | Sus scrofa | CB Cannabinoid Receptors | Peptides | Antibody | Neurobiology | Peptide Endocannabinoids | Endocannabinoid System | Monoclonal Antibodies | Negative Allosteric Modulators | Cannabinoids | CB1 | Hemoglobin | Pepcans | Antagonist
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 2, pp. 935 - 939
Journal Article
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2012, Volume 63, Issue 5, pp. 905 - 915
Mu-opioid and CB1-cannabinoid agonists produce analgesia; however, adverse effects limit use of drugs in both classes. Additive or synergistic effects... 
Analgesia | Morphine | Marijuana | G-protein | Adenylyl cyclase | CB1 receptors | AGONIST MORPHINE | ACTIVATION | PROTEIN-KINASE | CB1 CANNABINOID RECEPTOR | SYNERGISTIC INTERACTIONS | NEUROSCIENCES | INHIBITION | KAPPA | FULL AGONIST | ADENYLYL-CYCLASE | PHARMACOLOGY & PHARMACY | RAT-BRAIN | Pyrazoles - therapeutic use | Receptor, Cannabinoid, CB2 - agonists | Humans | Analgesics, Opioid - pharmacology | Receptors, Opioid, mu - agonists | Piperidines - pharmacology | Cannabinoid Receptor Agonists - therapeutic use | Recombinant Proteins - antagonists & inhibitors | Piperidines - metabolism | Receptors, Opioid, mu - metabolism | Morpholines - metabolism | Analgesics, Non-Narcotic - metabolism | Drug Inverse Agonism | Mice | Analgesics, Opioid - metabolism | Kinetics | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Analgesics, Opioid - antagonists & inhibitors | Cannabinoid Receptor Agonists - metabolism | Cricetulus | Analgesics, Non-Narcotic - pharmacology | Cannabinoid Receptor Agonists - pharmacology | Receptor, Cannabinoid, CB2 - genetics | Analgesics, Opioid - adverse effects | Narcotic Antagonists - metabolism | Receptor, Cannabinoid, CB1 - agonists | Analgesics, Non-Narcotic - adverse effects | Cannabinoid Receptor Agonists - adverse effects | Morpholines - adverse effects | CHO Cells | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Binding, Competitive | Recombinant Proteins - metabolism | Cricetinae | Morpholines - pharmacology | Narcotic Antagonists - adverse effects | Recombinant Proteins - agonists | Analgesics, Non-Narcotic - therapeutic use | Pyrazoles - metabolism | Mice, Inbred Strains | Receptors, Opioid, mu - antagonists & inhibitors | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Narcotic Antagonists - therapeutic use | Piperidines - therapeutic use | Narcotic Antagonists - pharmacology | Piperidines - adverse effects | Receptors, Opioid, mu - genetics | Index Medicus | Drugs | Pain perception | Opioid receptors | Cyclic AMP | Opioid receptors (type mu) | Antagonists | Cannabinoid CB1 receptors | Guanine nucleotide-binding protein | Antagonism | Cell activation | Side effects | Inverse agonists | CB1 Receptors | Adenylyl Cyclase
Journal Article
Neuropharmacology, ISSN 0028-3908, 06/2016, Volume 105, pp. 630 - 638
Journal Article
Philosophical Transactions: Biological Sciences, ISSN 0962-8436, 12/2012, Volume 367, Issue 1607, pp. 3353 - 3363
Human tissues express cannabinoid CB₁ and CB₂ receptors that can be activated by endogenously released 'endocannabinoids' or exogenously administered compounds... 
Receptors | Cannabinoids | Animal models | Pain | Medical treatment | Agonists | Morphine | Drug design | Endocannabinoids | Cannabinoid receptors | And CB2 | Blood-brain barrier | Cannabinoid receptor agonists | Δ9-tetrahydrocannabinol | Cannabinoid CB1 | Therapeutic applications and strategies | blood-brain barrier | Delta-tetrahydrocannabinol | cannabinoid CB1 and CB2 receptors | CB2 RECEPTOR | LIVER-DISEASES | AMYOTROPHIC-LATERAL-SCLEROSIS | ANXIETY-LIKE BEHAVIOR | MU-OPIOID RECEPTOR | RAT FORMALIN TEST | therapeutic applications and strategies | cannabinoid receptor agonists | NEUROPATHIC PAIN | MOUSE MODEL | BIOLOGY | PENTYLENETETRAZOLE-INDUCED SEIZURE | CENTRAL-NERVOUS-SYSTEM | Endocannabinoids - metabolism | Analgesics - pharmacology | Receptor, Cannabinoid, CB2 - agonists | Cardiovascular Diseases - drug therapy | Humans | Cannabinoid Receptor Agonists - pharmacology | Neurodegenerative Diseases - drug therapy | Pain - metabolism | Receptor, Cannabinoid, CB1 - agonists | Pain - drug therapy | Cannabinoid Receptor Agonists - therapeutic use | Dronabinol - pharmacology | Analgesics - therapeutic use | Cardiovascular Diseases - metabolism | Risk Assessment | Analgesics - administration & dosage | Clinical Trials as Topic | Neurodegenerative Diseases - metabolism | Blood-Brain Barrier - drug effects | Cannabinoid Receptor Agonists - administration & dosage | Drug Discovery | Blood-Brain Barrier - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Dronabinol - therapeutic use | Review
Journal Article
Neuropharmacology, ISSN 0028-3908, 12/2015, Volume 99, pp. 705 - 714
The synthetic cannabinoid 1-pentyl-3-(1-naphthoyl)-indole (JWH-018) has been detected in about 140 samples of a smokable herbal mixture termed “Spice”. JWH-018... 
Nucleus accumbens | Electrophysiology | Dopamine | Microdialysis | JWH-018 | CB1 receptor | BRAIN DOPAMINE | REWARD | NEUROSCIENCES | PREFRONTAL CORTEX | ADDICTION | DRUGS | NEURONS | DELTA-TETRAHYDROCANNABINOL | PHARMACOLOGY & PHARMACY | NUCLEUS-ACCUMBENS SHELL | RECEPTOR AGONIST | CB1 RECEPTORS | Species Specificity | Male | Ventral Tegmental Area - physiology | Nucleus Accumbens - physiology | Indoles - administration & dosage | Dose-Response Relationship, Drug | Self Administration | Prefrontal Cortex - drug effects | Receptor, Cannabinoid, CB1 - agonists | Dopaminergic Neurons - drug effects | Dopaminergic Neurons - physiology | Dopamine - metabolism | Ventral Tegmental Area - drug effects | Tissue Culture Techniques | Mice, Inbred C57BL | Inhibitory Postsynaptic Potentials - physiology | Cannabinoid Receptor Agonists - administration & dosage | Rats, Sprague-Dawley | Mice, Knockout | Receptor, Cannabinoid, CB1 - metabolism | Administration, Intravenous | Patch-Clamp Techniques | Animals | Receptor, Cannabinoid, CB1 - genetics | Naphthalenes - administration & dosage | Receptors, GABA-A - metabolism | Nucleus Accumbens - drug effects | Prefrontal Cortex - physiology | Inhibitory Postsynaptic Potentials - drug effects | Phenols | Marijuana | Neurosciences | Basic Medicine | Medical and Health Sciences | microdialysis | electrophysiology | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | nucleus accumbens | dopamine | Neurovetenskaper
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 02/2009, Volume 34, Issue 3, pp. 593 - 606
Journal Article