X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
p300/cbp-associated factor (85) 85
humans (63) 63
biochemistry & molecular biology (61) 61
acetylation (59) 59
animals (55) 55
index medicus (42) 42
p300 (35) 35
histone acetyltransferases (33) 33
histone acetyltransferase (30) 30
mice (30) 30
acetyltransferases - metabolism (28) 28
cell biology (26) 26
protein binding (26) 26
cell line (24) 24
creb-binding protein (24) 24
pcaf (23) 23
transcriptional activation (23) 23
histones - metabolism (21) 21
p300-cbp transcription factors - metabolism (21) 21
cbp-associated factor (19) 19
nuclear proteins - metabolism (18) 18
transcription factors - metabolism (18) 18
cbp (17) 17
p300-cbp transcription factors (17) 17
trans-activators - metabolism (17) 17
p300-cbp transcription factors - genetics (16) 16
cell cycle proteins - metabolism (15) 15
cell line, tumor (15) 15
chromatin (15) 15
expression (15) 15
oncology (15) 15
p300/cbp associated factor (15) 15
transcription factors (15) 15
transfection (15) 15
binding sites (14) 14
p53 (14) 14
protein structure, tertiary (14) 14
cancer (13) 13
histones (13) 13
phosphorylation (13) 13
transcription (13) 13
transcription, genetic (13) 13
amino acid sequence (12) 12
molecular sequence data (12) 12
acetyltransferases - genetics (11) 11
activation (11) 11
apoptosis (11) 11
gene expression (11) 11
in-vivo (11) 11
tumor suppressor protein p53 - metabolism (11) 11
cell cycle proteins - genetics (10) 10
gene-expression (10) 10
kinetics (10) 10
promoter regions, genetic (10) 10
protein (10) 10
research article (10) 10
saccharomyces cerevisiae proteins (10) 10
acetyltransferase (9) 9
binding (9) 9
cbp associated factor (9) 9
coenzyme-a (9) 9
dna-binding proteins - metabolism (9) 9
nuclear proteins - genetics (9) 9
proteins (9) 9
trans-activators - genetics (9) 9
biophysics (8) 8
chemistry, medicinal (8) 8
chromatin - metabolism (8) 8
enzymes (8) 8
gcn5 (8) 8
hela cells (8) 8
histone acetyltransferases - metabolism (8) 8
histone deacetylase (8) 8
promoter regions, genetic - genetics (8) 8
recombinant proteins - metabolism (8) 8
transcription factor (8) 8
transcription factors - chemistry (8) 8
acute myeloid-leukemia (7) 7
anacardic acid (7) 7
androgen receptor (7) 7
base sequence (7) 7
biochemical research methods (7) 7
crystal-structure (7) 7
dna - metabolism (7) 7
epigenetics (7) 7
inflammation (7) 7
nf-kappa-b (7) 7
pcaf, p300 (7) 7
substrate specificity (7) 7
transcriptional coactivator (7) 7
acetyltransferases - chemistry (6) 6
analysis (6) 6
article (6) 6
catalysis (6) 6
cbp, creb-binding protein (6) 6
creb-binding-protein (6) 6
dna-damage (6) 6
e1a-associated p300 protein - metabolism (6) 6
enzyme inhibitors - pharmacology (6) 6
hat, histone acetyltransferase (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Acta Pharmaceutica Sinica B, ISSN 2211-3835, 09/2015, Volume 5, Issue 5, pp. 378 - 389
Hypoxia-inducible factor-1 (HIF-1) has been recognized as an important cancer drug target. Many recent studies have provided convincing evidences of strong... 
Cancer drug discovery and development | HIF-1α inhibitors | HIF-1α | RCC, renal cell carcinoma | Ras, rat sarcoma | Raf, rapidly accelerated fibrosarcoma | EGF, epidermal growth factor | C-TAD, COOH-terminal TAD | HTS, high throughput screens | ARD-1, arrest-defective-1 | ELISA, enzyme-linked immunosorbent assay | pVHL, von Hippel-Lindau protein | LEP, leptin | ChIP, chromatin immunoprecipitation | IPAS, inhibitory PAS | IGF-BP3, IGF-factor-binding protein 3 | PAS, Per and Sim | mTOR, mammalian target of rapamycin | RT-PCR, reverse transcription polymerase chain reaction | CAC, circulating angiogenic cells | CoCl2, cobalt chloride | AKt, protein kinase B | TPT, topotecan | bHLH, basic-helix-loop-helix | LDHA, lactate dehydrogenase | GLUTs, glucose transporters | P, proline residue | ODDD, oxygen dependent degradation domain | TGF-α, transforming growth factor α | VEGF, vascular endothelial growth factor | CPTs, camptothecins | Mdm2, mouse double minute 2 homolog | PKM, pyruvate kinase M | AhR, aryl hydrocarbon receptor | K, lysine residue | IGF2, insulin-like growth factor 2 | GLUT3, glucose transporter 3 | CBP associated factor | eIF-4E, eukaryotic translation initiation factor 4E | MEK, MAPK | ADM, adrenomedullin | ARNT, aryl hydrocarbon nuclear translocator | HK2, hexokinase 2 | PHDs, prolyl-4-hydroxylases | PCAF, p300 | FIH-1, factor inhibiting HIF-1 | Review | SIRT 1, Sirtuin 1 | ERK kinase | C-MYC, myelocytomatosis virus oncogene cellular homolog | IGF-BP2, IGF-factor-binding protein 2 | N, asparagine residue | TAD, transactivation domains | HDAC, histone deacetylase | EMSA, electrophoretic mobility shift assay | LRP1, LDL-receptor-related protein 1 | Luc, luciferase | GAs, geldanamycins | HIF-1α, hypoxia-inducible factor-1α | HK1, hexokinase 1 | ID2, DNA-binding protein inhibitor | HPH, HIF-1 prolyl hydroxylases | NOS, nitric oxide synthase | N-TAD, NH2-terminal TAD | MNK, MAP kinase interacting kinase | MTs, microtubules | HRE, hypoxia response elements | ERK, extracellular signal-regulated kinase | EPO, erythropoietin | MAPK, mitogen-activated protein kinases | PI3K, phosphatidyl inositol-4,5-bisphosphate-3-kinase | DFO, deferoxamine | Top I, topoisomerase I | GLUT1, glucose transporter 1 | Hsp90, heat shock protein 90 | TGF-β3, transforming growth factor beta3 | 4E-BP1, eukaryotic translation initiation factor 4E (eIF-4E) binding protein p70 S6 kinase (S6K) | GA, geldanamycin
Journal Article
Biochemical Journal, ISSN 0264-6021, 03/2007, Volume 402, Issue 3, pp. 559 - 566
HATs (histone acetyltransferases) contribute to the regulation of gene expression, and loss or dysregulation of these activities may link to tumorigenesis.... 
Nuclear factor-erythroid 2 p45 subunit-related factor 2 (Nrf2) | Glutathione S-transferase placental form (GSTP) | Histone acetyltransferase (HAT) | Hepatocarcinogenesis | MafK | Monocytic leukaemia zinc-finger protein (MOZ) | PROTEIN | ACETYLATION | nuclear factor-erythroid 2 p45 subunit-related factor 2 (Nrf2) | BIOCHEMISTRY & MOLECULAR BIOLOGY | hepatocarcinogenesis | histone acetyltransferase (HAT) | ACUTE MYELOID-LEUKEMIA | glutathione S-transferase placental form (GSTP) | CELL-CYCLE PROGRESSION | PUTATIVE ACETYLTRANSFERASE | CHEMICAL HEPATOCARCINOGENESIS | ACUTE MONOCYTIC LEUKEMIA | TRANSFERASE-P GENE | TRANSCRIPTION FACTOR | monocytic leukaemia zinc-finger protein (MOZ) | PLACENTAL GLUTATHIONE TRANSFERASE | CCAAT-Enhancer-Binding Proteins - metabolism | Gene Expression | Glutathione S-Transferase pi - metabolism | Liver Neoplasms - genetics | Histone Acetyltransferases - genetics | Rats | Biomarkers, Tumor | Cell Transformation, Neoplastic - metabolism | Promoter Regions, Genetic - genetics | Animals | MafK Transcription Factor - genetics | MafK Transcription Factor - metabolism | Cell Transformation, Neoplastic - genetics | Histone Acetyltransferases - metabolism | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | Protein Binding | Liver Neoplasms - pathology | NF-E2-Related Factor 2 - genetics | Mice | Cell Transformation, Neoplastic - pathology | Liver Neoplasms - enzymology | Dimerization | Glutathione S-Transferase pi - genetics | AAF, 2-acetylaminofluorene | GPE, GSTP enhancer | TRE, PMA (‘TPA’)-responsive element | bZIP, basic region leucine zipper | HBO1, HAT binding to ORC1 (origin recognition complex subunit 1) | CAF, p300 | Sas3, Sas2 and TIP60 | CREB, cAMP-response-element-binding protein | PHD, plant homeodomain | DTT, dithiothreitol | GSTP, GST placental form | Nrf2, nuclear factor-erythroid 2 p45 subunit-related factor 2 | MOZ, monocytic leukaemia zinc-finger protein | RT, reverse transcriptase | TIF2, transcriptional intermediary factor 2, TIP60, Tat-interacting protein, 60 kDa | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | MYST, MOZ, Ybf2 | MORF, MOZ related factor | GST, glutathione S-transferase | CBP-associated factor | FBS, fetal bovine serum | ORF, open reading frame | HA, haemagglutinin | HAT, histone acetyltransferase | PH, partial hepatectomy | CBP, CREB-binding protein | AML1, acute myeloid leukaemia 1 | GCN5, positive general control of transcription-5 | ING, inhibitor of growth | DEN, diethylnitrosoamine | nuclear factor- erythroid 2 p45 subunit-related factor 2 (Nrf2)
Journal Article
by Chung, S and Kim, S and Son, M and Kim, M and Koh, ES and Shin, SJ and Park, CW and Kim, HS
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 03/2019, Volume 20, Issue 7, p. 1554
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2000, Volume 275, Issue 29, pp. 21953 - 21959
Journal Article
Neuroscience, ISSN 0306-4522, 2010, Volume 167, Issue 3, pp. 850 - 863
Abstract p300/CREB binding protein-associated factor (PCAF) regulates gene expression by acting through histone acetylation and as a transcription coactivator.... 
Neurology | amyloid toxicity | Aβ 25–35 peptide | memory | neprilysin | acetyltransferase PCAF | peptide | Neprilysin | Amyloid toxicity | Memory | Acetyltransferase PCAF | ALZHEIMERS-DISEASE | DEPENDENT TRANSCRIPTIONAL CONTROL | NEUROSCIENCES | PIQUARD ET-AL | DEGRADING ENZYME NEPRILYSIN | RAT TEMPORAL CORTEX | P300/CBP-ASSOCIATED FACTOR PCAF | A-BETA | A beta(25-35) peptide | SOMATOSTATIN-LIKE IMMUNOREACTIVITY | PRECURSOR PROTEIN | INTRACELLULAR DOMAINS | Neurons - pathology | Memory Disorders - genetics | Apoptosis - drug effects | Peptide Fragments - toxicity | Memory Disorders - metabolism | Nerve Degeneration - genetics | Apoptosis - genetics | Hippocampus - drug effects | Nerve Degeneration - chemically induced | Nerve Degeneration - metabolism | Brain - metabolism | Somatostatin - drug effects | p300-CBP Transcription Factors - genetics | Presenilins - metabolism | Amyloid beta-Peptides - metabolism | Presenilins - genetics | Neprilysin - genetics | Neurons - metabolism | Neurons - drug effects | Somatostatin - metabolism | Disease Models, Animal | Alzheimer Disease - physiopathology | Genetic Predisposition to Disease - genetics | Neprilysin - drug effects | Peptide Fragments - metabolism | Amyloid beta-Peptides - toxicity | Brain - physiopathology | Oxidative Stress - genetics | Hippocampus - pathology | Neprilysin - metabolism | Mice, Knockout | Drug Resistance - genetics | Hippocampus - metabolism | Animals | Alzheimer Disease - metabolism | Mice | Oxidative Stress - drug effects | Alzheimer Disease - genetics | Presenilins - drug effects | Memory Disorders - chemically induced | Index Medicus | Acetylation
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2000, Volume 19, Issue 24, pp. 6792 - 6803
Journal Article