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cbp/p300 (326) 326
humans (186) 186
biochemistry & molecular biology (160) 160
animals (132) 132
index medicus (123) 123
p300 (114) 114
cbp (95) 95
acetylation (87) 87
activation (82) 82
cell biology (79) 79
trans-activators - metabolism (79) 79
transcriptional activation (77) 77
proteins (71) 71
protein binding (70) 70
nuclear proteins - metabolism (68) 68
mice (67) 67
transcription (66) 66
cell line (57) 57
creb-binding protein (54) 54
phosphorylation (54) 54
expression (53) 53
molecular sequence data (51) 51
histone acetyltransferase (49) 49
transcription factors - metabolism (49) 49
amino acid sequence (47) 47
transcription factors (47) 47
coactivator (46) 46
signal transduction (46) 46
oncology (45) 45
dna-binding proteins - metabolism (44) 44
research (44) 44
cbp/p300 protein (43) 43
gene expression (41) 41
gene-expression (41) 41
protein structure, tertiary (41) 41
trans-activators - genetics (41) 41
transcription, genetic (41) 41
article (39) 39
protein (39) 39
binding (38) 38
histone acetyltransferases (37) 37
chromatin (36) 36
genetics & heredity (36) 36
cancer (35) 35
biophysics (34) 34
cell line, tumor (34) 34
gene (34) 34
transfection (34) 34
coactivators (33) 33
genetic aspects (32) 32
multidisciplinary sciences (32) 32
promoter regions, genetic (32) 32
creb-binding-protein (31) 31
mutation (31) 31
p300-cbp transcription factors - metabolism (31) 31
p53 (31) 31
binding sites (30) 30
female (29) 29
gene expression regulation (29) 29
nuclear proteins - genetics (29) 29
models, molecular (28) 28
trans-activators - chemistry (28) 28
transactivation (28) 28
complex (27) 27
histones - metabolism (27) 27
male (27) 27
apoptosis (26) 26
cos cells (26) 26
genetic transcription (26) 26
differentiation (25) 25
nf-kappa-b (25) 25
transcription factors - genetics (25) 25
genes (24) 24
histones (24) 24
nuclear proteins - chemistry (24) 24
e1a-associated p300 protein - metabolism (23) 23
promoter (23) 23
acetyltransferases - metabolism (22) 22
cells, cultured (22) 22
dna-binding proteins - genetics (22) 22
analysis (21) 21
creb-binding protein - metabolism (21) 21
growth (21) 21
transcription factors - chemistry (21) 21
cbp/p300 bromodomain (20) 20
dna-binding (20) 20
physiological aspects (20) 20
research article (20) 20
tgf-beta (20) 20
tumor suppressor protein p53 - metabolism (19) 19
cell nucleus - metabolism (18) 18
cells (18) 18
genes, reporter (18) 18
hela cells (18) 18
nf-kappa b (18) 18
nf-κb (18) 18
recombinant fusion proteins - metabolism (18) 18
acetyltransferase (17) 17
biological sciences (17) 17
domain (17) 17
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06/2012
Forkhead box Class O (FOXO), one subfamily of the Forkhead box (Fox) family, which is featured by the Forkhead (FH) DNA-binding domain, includes four human... 
NMR | 0786 | Transcription | CBP/p300 | FOXO3a | p53 | Apoptosis
Dissertation
Gene, ISSN 0378-1119, 04/2000, Volume 246, Issue 1-2, pp. 9 - 21
The vitamin D receptor regulates transcription in direct response to its cognate hormonal ligand, 1,25(OH) D . Ligand binding leads to the recruitment of... 
1,25(OH) | Transcription | DRIP | CBP/p300 | SRC-1
Journal Article
Gene, ISSN 0378-1119, 10/2019, Volume 717, p. 143998
Eid1 is a member of the EID protein family, which regulates differentiation, transcription and acetyltransferase activity. Accumulating evidence suggests that... 
CBP/P300 | Neural stem cells | Differentiation | Histone acetyltransferase | Neural inflammation
Journal Article
Experimental Gerontology, ISSN 0531-5565, 10/2019, Volume 126, p. 110690
SKN-1/Nrf transcription factors regulate diverse biological processes essentially stress defense, detoxification, and longevity. Studies in model organisms... 
Aging | Oxidative stress | C. elegans | SKN-1/Nrf | CBP/p300
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2016, Volume 59, Issue 4, pp. 1350 - 1356
Novel ligands of the CREBBP bromodomain were identified by fragment-based docking. The in silico discovered hits have been optimized by chemical synthesis into... 
CHEMISTRY, MEDICINAL | THERAPY | SMALL-MOLECULE INHIBITORS | I-BET762 | BINDING-PROTEIN | CBP/P300 | OPTIMIZATION | ACETYL-LYSINE INTERACTIONS | ACUTE MYELOID-LEUKEMIA | DISCOVERY | ACETYLTRANSFERASE
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 09/2005, Volume 25, Issue 18, pp. 7966 - 7975
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
INDEPENDENT MECHANISM | TRANSCRIPTIONAL ACTIVATION | P65 SUBUNIT | IN-VITRO | DEPENDENT TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | KINASE | CBP/P300 | HISTONE MODIFICATIONS | P53 | CELL BIOLOGY | Gene Expression
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 1901, Volume 17, Issue 3, pp. 720 - 730
Inhibitors that prevent the binding of bromodomains to acetylated histones hold therapeutic potential. However, the effects of targeting most of the 60... 
ANDROGEN RECEPTOR | ONCOLOGY | P300 | TRANSCRIPTION | CREB-BINDING-PROTEIN | CBP/P300 BROMODOMAIN | TARGETS | OPTIMIZATION | IDENTIFICATION | DISCOVERY | SMALL-MOLECULE INHIBITOR | CELL BIOLOGY
Journal Article
Journal of Natural Products, ISSN 0163-3864, 07/2018, Volume 81, Issue 7, pp. 1645 - 1650
Swinhoeisterols C-F (1-4), four new steroids having a rearranged 6/6/5/7 ring system, were isolated from the Xisha sponge Theonella swinhoei, together with the... 
CHEMISTRY, MEDICINAL | P300 | A-C | CBP/P300 | PHARMACOLOGY & PHARMACY | 4-METHYLENESTEROLS | INHIBITORS | ACETYLTRANSFERASE | CYCLIC PENTAPEPTIDES | PLANT SCIENCES
Journal Article
Biochemistry, ISSN 0006-2960, 03/2019, Volume 58, Issue 10, pp. 1354 - 1362
The intrinsically disordered transactivation domains of HIF-1 alpha and CITED2 compete for binding of the TAZ1 domain of the CREB-binding protein by a... 
MAGNETIC-RESONANCE RELAXATION | INTRINSIC DISORDER | NMR | MECHANISM | MACROMOLECULES | STRUCTURAL BASIS | TRANSACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CBP/P300 | PEPTIDE | MODEL-FREE APPROACH
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 06/2019, Volume 853, pp. 308 - 315
Microbiota produce short chain fatty acids (SCFAs), which are known to maintain gut homeostasis, by the fermentation of dietary fiber in the human colon. Among... 
SMCT-1 | Homeostasis | Prostanoid EP4 receptor | CBP/p300 | Colorectal cancer | Butyrate | ACTIVATION | STIMULATION | PROTEIN | CHROMATIN | PHOSPHORYLATION | PHOSPHATIDYLINOSITOL 3-KINASE | PHENOTYPE | E-2 | HISTONE ACETYLATION | GROWTH | PHARMACOLOGY & PHARMACY | Index Medicus
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 04/2019, Volume 58, Issue 16, pp. 2133 - 2143
p300 and CBP are highly related histone acetyltransferase (HAT) enzymes that regulate gene expression, and their dysregulation has been linked to cancer and... 
CBP | ANDROGEN RECEPTOR | RECEPTOR SPLICE VARIANTS | CANCER EPIGENETICS | CHROMATIN | HISTONE H3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CBP/P300 BROMODOMAIN | GENOME-WIDE | LYSINE ACETYLATION | CATALYTIC CORE
Journal Article
Immunity, ISSN 1074-7613, 2010, Volume 32, Issue 3, pp. 317 - 328
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 06/2011, Volume 18, Issue 6, pp. 937 - 947
Neuronal apoptosis plays a major role during development and aberrant apoptosis contributes to the pathology of certain neurological conditions. Studies with... 
Journal Article
Current Opinion in Chemical Biology, ISSN 1367-5931, 08/2016, Volume 33, pp. 58 - 66
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 02/2019, Volume 240, Issue 2, pp. 257 - 269
Fat remodeling has been extensively explored through protein deacetylation, but not yet acetylation, as a viable therapeutic approach in the management of... 
fat remodeling | adipocyte | browning | Cbp/p300 | acetyltransferase | lipodystrophy | obesity | P300 | TISSUE | SIRT1 | CBP | ENERGY HOMEOSTASIS | INSULIN-RESISTANCE | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | FAT | MICE | BROWN
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 04/2016, Volume 106, pp. 1 - 18
Bromodomains are epigenetic readers of histone acetylation involved in chromatin remodeling and transcriptional regulation. The human proteome comprises 46... 
BET proteins | Acetylated histones | Drug discovery | Epigenetic drugs | Bromodomains | SELECTIVE-INHIBITION | EPIGENETIC READERS | TRANSCRIPTIONAL ACTIVITY | DISPLACEMENT ASSAYS | SYNERGISTIC ACTIVITY | FRAGMENT-BASED DISCOVERY | SMALL-MOLECULE INHIBITORS | CBP/P300 BROMODOMAIN | CHEMICAL PROBE | PHARMACOLOGY & PHARMACY | Chromatin - metabolism | Transcription, Genetic - drug effects | Transcription Factors - chemistry | Histones - chemistry | Triazoles - chemistry | Cardiovascular Diseases - drug therapy | Humans | Cardiovascular Diseases - pathology | Cardiovascular Diseases - genetics | Autoimmune Diseases - genetics | Azepines - chemistry | Neoplasms - genetics | Antineoplastic Agents - pharmacology | Epigenesis, Genetic - drug effects | Acetylation | Autoimmune Diseases - pathology | Chromatin - drug effects | Histones - antagonists & inhibitors | Autoimmune Diseases - drug therapy | Chromatin - chemistry | Benzodiazepines - pharmacology | Chromatin Assembly and Disassembly | Models, Molecular | Transcription Factors - antagonists & inhibitors | Cardiotonic Agents - chemistry | Cardiotonic Agents - pharmacology | Transcription Factors - genetics | Antineoplastic Agents - chemistry | Drug Discovery | Neoplasms - drug therapy | Azepines - pharmacology | Triazoles - pharmacology | Histones - genetics | Benzodiazepines - chemistry | Neoplasms - pathology | Irritable bowel syndrome | Life Sciences | Biochemistry, Molecular Biology | Biomolecules
Journal Article
Journal Article