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EMBO Journal, ISSN 0261-4189, 2013, Volume 32, Issue 5, pp. 629 - 644
Journal Article
Journal Article
Journal Article
Current Opinion in Immunology, ISSN 0952-7915, 08/2018, Volume 53, pp. 167 - 172
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2016, Volume 126, Issue 6, pp. 2167 - 2180
Lymphangiogenesis is supported by 2 homologous VEGFR3 ligands, VEGFC and VEGFD. VEGFC is required for lymphatic development, while VEGFD is not. VEGFC and... 
VASCULAR DEVELOPMENT | MEDICINE, RESEARCH & EXPERIMENTAL | EMBRYONIC LYMPHANGIOGENESIS | SKELETAL-MUSCLE | CCBE1 | LYMPHATIC VESSELS | FACTOR-C | TYROSINE KINASES | LIGAND | LYMPHEDEMA | ENDOTHELIAL GROWTH-FACTOR | Cell Proliferation | Humans | Vascular Endothelial Growth Factor D - deficiency | Vascular Endothelial Growth Factor C - deficiency | ADAMTS Proteins - deficiency | Lymphatic Vessels - metabolism | Procollagen N-Endopeptidase - metabolism | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | HEK293 Cells | Vascular Endothelial Growth Factor D - genetics | Peptide Hydrolases - metabolism | Calcium-Binding Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Signal Transduction | ADAMTS Proteins - metabolism | Endothelial Cells - metabolism | Procollagen N-Endopeptidase - genetics | Lymphangiogenesis - physiology | Calcium-Binding Proteins - deficiency | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Vascular Endothelial Growth Factor D - metabolism | Animals | Endothelial Cells - cytology | Models, Biological | Vascular Endothelial Growth Factor C - metabolism | Ligands | Mice | Lymphangiogenesis - genetics | ADAMTS Proteins - genetics | Calcium-Binding Proteins - genetics | Genetic aspects | Neovascularization | Proteolysis | Vascular endothelial growth factor | Health aspects | Studies | Lymphatic system | Lymphedema | Rodents | Cloning | Zebrafish | Skin | Experiments | Defects
Journal Article
Journal Article
by Song, JL and Chen, W and Cui, XW and Huang, ZY and Wen, DP and Yang, YL and Yu, W and Cui, L and Liu, CY
THERANOSTICS, ISSN 1838-7640, 2020, Volume 10, Issue 5, pp. 2327 - 2341
Collagen and calcium-binding EGF domain-1 (CCBE1) is essential for lymphatic vascular development as it promotes vascular endothelial growth factor C (VEGFC)... 
MEDICINE, RESEARCH & EXPERIMENTAL | CCBE1 | CELLS | colorectal cancer | VEGFC | MECHANISMS | FIBROBLASTS | COLON-CANCER | TGF-beta | INHIBITION | POOR-PROGNOSIS | tumor lymphangiogenesis | GENE-EXPRESSION | MUTATIONS | lymphatic metastasis
Journal Article
Molecular Syndromology, ISSN 1661-8769, 03/2013, Volume 4, Issue 3, pp. 107 - 113
The lymphedema-lymphangiectasia-intellectual disability (Hennekam) syndrome (HS) is characterised by a widespread congenital lymph vessel dysplasia manifesting... 
Original Article | Lymphatic dysplasia | CCBE1 | Autosomal recessive | Lymphedema | Lymphangiectasia | Hennekam syndrome | Genotype-phenotype | Original
Journal Article
Genes and Development, ISSN 0890-9369, 08/2015, Volume 29, Issue 15, pp. 1618 - 1630
Journal Article
Development (Cambridge), ISSN 0950-1991, 02/2017, Volume 144, Issue 3, pp. 507 - 518
Vascular endothelial growth factors (VEGFs) control angiogenesis and lymphangiogenesis during development and in pathological conditions. In the zebrafish... 
Kdr | Lymphatic | Lymphangiogenesis | Vegfd | Vegfc | Flt4 | VASCULAR DEVELOPMENT | CCBE1 | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | DEVELOPMENTAL BIOLOGY | D PROMOTES | MORPHOGENESIS | NETWORK FORMATION | MUTATIONS | LIGAND | REVEALS | Sequence Deletion | Up-Regulation | Vascular Endothelial Growth Factor Receptor-1 - physiology | Zebrafish - embryology | Vascular Endothelial Growth Factor Receptor-2 - genetics | Membrane Proteins - physiology | Vascular Endothelial Growth Factor Receptor-2 - physiology | Vascular Endothelial Growth Factor D - genetics | Intracellular Signaling Peptides and Proteins - genetics | Vascular Endothelial Growth Factor Receptor-1 - genetics | Vascular Endothelial Growth Factor D - physiology | Vascular Endothelial Growth Factor C - physiology | Signal Transduction | Membrane Proteins - genetics | Neovascularization, Physiologic - genetics | Lymphangiogenesis - physiology | Vascular Endothelial Growth Factor C - genetics | Zebrafish - genetics | Zebrafish Proteins - physiology | Neovascularization, Physiologic - physiology | Animals | Mutagenesis | Models, Biological | Zebrafish - physiology | Zebrafish Proteins - genetics | Intracellular Signaling Peptides and Proteins - physiology | Lymphangiogenesis - genetics | Angiogenesis | Embryogenesis | Epistasis | Genomes | Growth factors | Arteries | Vascular endothelial growth factor receptors
Journal Article