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American journal of respiratory cell and molecular biology, ISSN 1044-1549, 11/2015, Volume 53, Issue 5, pp. 676 - 688
Macrophages are dynamic cells that mature under the influence of signals from the local microenvironment into either classically (M1) or alternatively (M2)... 
classically activated macrophages (CAM/M1) | Phagocytosis/ endocytosis | phagocytosis/endocytosis | phenotypic stability | alternatively activated macrophages (AAM/M2) | reprogramming of polarization | PHAGOCYTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOCYTES | DIFFERENTIAL REGULATION | MURINE | CELL BIOLOGY | GM-CSF | RESPIRATORY SYSTEM | THP-1 CELLS | MANNOSE | RECEPTOR-ACTIVITY | POLARIZATION | EXPRESSION | Chemokines, CC - secretion | Gene Expression - drug effects | Monocytes - cytology | Humans | Monocytes - immunology | Chemokine CCL5 - secretion | Chemokine CCL17 - secretion | Chemokine CXCL10 - biosynthesis | Interleukin-4 - pharmacology | Chemokine CCL17 - biosynthesis | Gene Expression - immunology | Chemokines, CC - biosynthesis | Interleukin-8 - secretion | Cell Differentiation | Interleukin-1beta - biosynthesis | Macrophages - immunology | Endocytosis - immunology | Interleukin-1beta - secretion | Interleukin-8 - biosynthesis | Endocytosis - drug effects | Tumor Necrosis Factor-alpha - secretion | Immunophenotyping | Macrophages - cytology | Interleukin-13 - pharmacology | Monocytes - drug effects | Chemokine CCL5 - biosynthesis | Chemokine CXCL10 - secretion | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Primary Cell Culture | Macrophage Activation - drug effects | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - pharmacology | Studies | Biology | Immunology | Blood & organ donations | Cytokines | Gene expression
Journal Article
Glia, ISSN 0894-1491, 10/2018, Volume 66, Issue 10, pp. 2246 - 2261
Chemokines are important signaling molecules in the immune and nervous system. Using a fluorescence reporter mouse model, we demonstrate that the chemokine... 
CCL22 | hippocampus | microglia morphology | LPS‐induced inflammation | neuromodulatory chemokines | neuron–glia cross‐talk | CCL17 | neuron–glia cross-talk | LPS-induced inflammation | SEIZURE SUSCEPTIBILITY | CHEMOKINE RECEPTOR 4 | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | neuron-glia cross-talk | DENDRITIC CELLS | DEFICIENT MICE | NEUROSCIENCES | MICROGLIA | INFLAMMATION | IN-VIVO | CENTRAL-NERVOUS-SYSTEM | PLASTICITY | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Neurons - pathology | Synaptic Transmission - physiology | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Chemokine CCL17 - genetics | Male | Neuroimmunomodulation - physiology | Green Fluorescent Proteins - genetics | Monocytes - immunology | Chemokine CCL22 - metabolism | Lipopolysaccharides | Receptors, CCR4 - metabolism | Inflammation - metabolism | Microglia - immunology | Monocytes - pathology | Microglia - pathology | Female | Green Fluorescent Proteins - metabolism | Gene Expression | Hippocampus - immunology | Mice, Inbred C57BL | Neurons - immunology | Mice, Transgenic | Hippocampus - pathology | Animals | Homeostasis - physiology | Chemokine CCL17 - metabolism | Neurons | Neuroimaging | Brain | Cytology | Fluorescence | Nervous system | Cerebrospinal fluid | Macrophages | Cell surface | Neuromodulation | CCL22 protein | Synaptic transmission | Rodents | Tumor necrosis factor-TNF | CCL17 protein | Trees | Inflammation | Microglia | Signaling | Tumor necrosis factor | Morphology | Mice | Leukocytes (granulocytic) | Surface area | Hippocampus | Chemokines
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 11/2017, Volume 18, Issue 11, p. 2306
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). It affects more than two million people worldwide,... 
Multiple sclerosis | CCL22 | Cns autoimmunity | Dendritic cells | Migration | Experimental autoimmune encephalomyelitis | Neuroinflammation | CCL17 | CCR4 | Chemokines | ENCEPHALOMYELITIS | HUMAN MICROGLIA | MACROPHAGE-DERIVED CHEMOKINE | multiple sclerosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | chemokines | CEREBROSPINAL-FLUID | CHEMISTRY, MULTIDISCIPLINARY | CUTTING EDGE | CNS autoimmunity | experimental autoimmune encephalomyelitis | dendritic cells | MULTIPLE-SCLEROSIS | neuroinflammation | migration | REGULATORY T-CELLS | CENTRAL-NERVOUS-SYSTEM | EXPRESSION | Receptors, CCR4 - immunology | Dendritic Cells - immunology | Humans | Central Nervous System - pathology | Dendritic Cells - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Autoimmune Diseases of the Nervous System - pathology | Central Nervous System - immunology | Receptors, CCR4 - analysis | Chemokine CCL22 - analysis | Chemokine CCL22 - immunology | Autoimmunity - immunology | Chemokine CCL17 - immunology | Dendritic Cells - drug effects | Molecular Targeted Therapy - methods | Encephalomyelitis, Autoimmune, Experimental - pathology | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Autoimmune Diseases of the Nervous System - drug therapy | Autoimmune Diseases of the Nervous System - immunology | Chemokine CCL17 - analysis | Animals | Central Nervous System - drug effects | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Multiple Sclerosis - drug therapy | Encephalomyelitis | Pathogenesis | Central nervous system | Homeostasis | Nervous system | Antagonists | Lymphocytes T | CC chemokines | Proteins | CCL22 protein | Receptors | Demyelination | Lymphocytes | Protein transport | CCL17 protein | Carbon-carbon composites | Cellular manufacture | Antigen presentation | Immunization | Myelin | Experimental allergic encephalomyelitis | CD4 antigen | White blood cells | Neurological complications | Ligands | Adults | Autoimmune diseases
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2012, Volume 18, Issue 7, pp. 1925 - 1935
Purpose: Respiratory papillomas, caused by human papillomaviruses types 6 and 11 (HPV6/11), are premalignant lesions with potential for malignant conversion.... 
MYCOBACTERIUM-TUBERCULOSIS | RECRUITMENT | POPULATION | RESPONSIVENESS | HOMEOSTASIS | ONCOLOGY | TRANSCRIPTION FACTOR FOXP3 | PD-1 | LINEAGE | VIRAL-INFECTION | LYMPHOCYTES | Forkhead Transcription Factors - immunology | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Human papillomavirus 6 - immunology | Humans | Gene Expression Regulation, Neoplastic | Programmed Cell Death 1 Ligand 2 Protein - metabolism | Chemokine CCL17 - genetics | Male | Precancerous Conditions - metabolism | Chemokine CCL22 - metabolism | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Chemokine CCL22 - immunology | Flow Cytometry | Forkhead Transcription Factors - metabolism | Leukocytes, Mononuclear - immunology | Chemokine CCL17 - immunology | Papillomavirus Infections - immunology | Female | Human papillomavirus 11 - immunology | Papilloma - metabolism | Papilloma - genetics | Respiratory Tract Neoplasms - immunology | Respiratory Tract Neoplasms - genetics | Programmed Cell Death 1 Ligand 2 Protein - genetics | CD4-Positive T-Lymphocytes - metabolism | Programmed Cell Death 1 Receptor - metabolism | Reverse Transcriptase Polymerase Chain Reaction | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Precancerous Conditions - genetics | Respiratory Tract Neoplasms - metabolism | Papillomavirus Infections - genetics | Programmed Cell Death 1 Ligand 2 Protein - immunology | Tumor Microenvironment - immunology | B7-H1 Antigen - metabolism | Chemokine CCL22 - genetics | Precancerous Conditions - immunology | Papillomavirus Infections - metabolism | Papilloma - immunology | Programmed Cell Death 1 Receptor - immunology | Chemokine CCL17 - metabolism | Programmed Cell Death 1 Receptor - genetics | PD-L1 | PD-L2 | immune suppression | CCL17 | Tregs | Recurrent Respiratory Papillomatosis
Journal Article
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2014, Volume 447, Issue 2, pp. 278 - 284
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 3, pp. 710 - 719
Background The Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and severe asthma and nonatopic... 
Allergy and Immunology | phenotypes | type 2 inflammation | airway mucosal gene expression | biomarkers | Asthma | CYTOKINES | MEPOLIZUMAB | EOSINOPHILS | VALIDATION | MONOCLONAL-ANTIBODY | IMMUNOLOGY | PERIOSTIN | EPITHELIAL-CELLS | ALLERGY | EXHALED NITRIC-OXIDE | EXPRESSION | EOTAXIN | Asthma - metabolism | Chemokines, CC - blood | Humans | Middle Aged | Interleukin-13 - immunology | Male | Cell Adhesion Molecules - immunology | Chemokine CCL26 | Eosinophils - immunology | Young Adult | Interleukin-13 - genetics | Asthma - blood | Respiratory Mucosa - immunology | Asthma - immunology | Chemokine CCL17 - immunology | Adult | Female | Chemokines, CC - immunology | Leukocyte Count | Chemokine CCL17 - blood | Biomarkers - metabolism | Severity of Illness Index | Cell Line | Gene Expression | Asthma - physiopathology | Biomarkers - blood | Adolescent | Respiratory Function Tests | Nitric Oxide - metabolism | Medical research | Genes | Immunoglobulin E | Inflammation | Gene expression | Cells | Homeopathy | Materia medica and therapeutics | Nitric oxide | Therapeutics | Medicine, Experimental | Biological markers | Cytokines | Leukocytes (eosinophilic) | Mucosa | Smooth muscle | Population studies | Interleukin 13 | Kinases | Patients | Respiratory tract | Biopsy | Cell lines | Biomarkers | Bioindicators | CCL17 protein | Chemokines
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 6, pp. 1404 - 1412.e7
Background Studies with monocyte-derived macrophages (MDMs) and animal models have suggested a role for alternatively activated (M2) macrophages in asthmatic... 
Allergy and Immunology | macrophage | chemokine | Asthma | steroid | BRONCHOALVEOLAR LAVAGE FLUID | FLOW-CYTOMETRIC METHOD | REGULATED CHEMOKINE | ALLERGIC AIRWAY INFLAMMATION | IMMUNOLOGY | ALVEOLAR MACROPHAGE | ALTERNATIVELY ACTIVATED MACROPHAGES | IN-VITRO | ALLERGY | INDUCED SPUTUM | CORTICOSTEROID INSENSITIVITY | T-CELLS | Biomarkers - metabolism | Up-Regulation | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Middle Aged | Morpholines - pharmacology | Chemokine CCL17 - genetics | Male | Th2 Cells - immunology | Asthma - drug therapy | Eosinophils - immunology | Young Adult | Phenotype | Sputum - immunology | Sputum - drug effects | Asthma - immunology | Adult | Female | Macrophages - drug effects | Chromones - pharmacology | Chemokine CCL17 - metabolism | Macrophages - immunology | Adrenal Cortex Hormones - administration & dosage | Universities and colleges | Macrophages | Analysis | Proteins | Flow cytometry | Genotype & phenotype | Lymphocytes | Biomarkers | Ligands | Drug therapy | Gene expression | Chemokines | Immune system | Corticoids | Animal models | Lung | Helper cells | Lymphocytes T | mRNA | CCL22 protein | Respiratory tract diseases | Alveoli | CCL17 protein | Enzymes | Cytokines | biomarkers | Bronchus | Inflammation | Eosinophilia | 1-Phosphatidylinositol 3-kinase | CD163 antigen | Monocytes | Interleukin 10 | Sputum | Steroid hormones
Journal Article
Journal Article