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Journal Article
Journal Article
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2008, Volume 370, Issue 2, pp. 274 - 278
In the process of cardiac remodeling, connective tissue growth factor (CTGF/CCN2) is secreted from cardiac myocytes. Though CTGF is well known to promote... 
Connective tissue growth factor | CCN family | Cardiac myocyte | Akt | Hypertrophy | MYOCYTES | hypertrophy | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | TRANSCRIPTION | RATS | CARDIOMYOCYTES | cardiac myocyte | FIBROBLASTS | connective tissue growth factor | BIOPHYSICS | GENE | PATHWAY | EXPRESSION | CONTRIBUTES | Gene Expression - drug effects | Cardiomegaly - pathology | Proto-Oncogene Proteins c-akt - genetics | Intercellular Signaling Peptides and Proteins - physiology | Amino Acids - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Immediate-Early Proteins - physiology | Signal Transduction | Cell Size - drug effects | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Rats | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Myocytes, Cardiac - pathology | Animals | Immediate-Early Proteins - genetics | Myocytes, Cardiac - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Immediate-Early Proteins - pharmacology | Myocytes, Cardiac - metabolism | Cardiomegaly - genetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Cardiomegaly - metabolism | Connective Tissue Growth Factor | Heart enlargement | Growth factors | ACTIN | 60 APPLIED LIFE SCIENCES | GROWTH FACTORS | GTP-ASES | HYPERTROPHY | PEPTIDES | LIGANDS | BIOLOGICAL EFFECTS | AMINO ACIDS | PHOSPHOTRANSFERASES | RECEPTORS | CONNECTIVE TISSUE
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 10/2012, Volume 47, Issue 4, pp. 528 - 535
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e78022
Oral squamous cell carcinoma (OSCC) has a tendency to migrate and metastasize. WNT1-inducible signaling pathway protein 1 (WISP-1) is a cysteine-rich protein... 
LUNG-CANCER | ICAM-1 EXPRESSION | CCN FAMILY | INCREASES MIGRATION | HUMAN OSTEOSARCOMA | MULTIDISCIPLINARY SCIENCES | GROWTH-FACTOR | ADHESION MOLECULES | INFLAMMATORY BREAST-CANCER | UP-REGULATION | HUMAN CHONDROSARCOMA CELLS | Proto-Oncogene Proteins - metabolism | CCN Intercellular Signaling Proteins - genetics | MAP Kinase Kinase Kinase 5 - genetics | Signal Transduction | Transcription Factor AP-1 - genetics | Antibodies, Monoclonal - pharmacology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Proto-Oncogene Proteins - genetics | Transcription Factor AP-1 - metabolism | Cell Movement - genetics | Cell Movement - physiology | Integrin alphaVbeta3 - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Intercellular Adhesion Molecule-1 - genetics | CCN Intercellular Signaling Proteins - metabolism | Cell Line, Tumor | MAP Kinase Kinase Kinase 5 - metabolism | Integrin alphaVbeta3 - antagonists & inhibitors | Monoclonal antibodies | Cysteine | Squamous cell carcinoma | Cellular signal transduction | Integrins | Apoptosis | Biotechnology | Transcription factors | Motility | Oral cancer | Lung cancer | Activation | Arthritis | Metastasis | Kinases | Cell adhesion & migration | Proteins | Signal transduction | Epidermal growth factor | Medical laboratories | Rodents | Penicillin | Cell adhesion | Fibroblasts | CYR61 protein | Tumorigenesis | Pretreatment | Immunoglobulins | Intercellular adhesion molecule 1 | Activator protein 1 | MAP kinase | Connective tissue growth factor | JNK protein | Breast cancer | Oral squamous cell carcinoma | Signaling | Medical prognosis | Transduction | Cell migration
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e94751
Cancer cells that survive fractionated irradiation can be radioresistant and cause tumor recurrence. However, the molecular mechanisms underlying the... 
APOPTOSIS | ACTIVATION | CHK2 | MULTIDISCIPLINARY SCIENCES | MITOTIC CATASTROPHE | DEATH | BETA-CATENIN | CANCER | P53 | CCN Intercellular Signaling Proteins - genetics | Tumor Burden - radiation effects | Humans | Culture Media, Conditioned - pharmacology | Esophageal Neoplasms - radiotherapy | Esophageal Neoplasms - pathology | Extracellular Space - metabolism | Esophageal Neoplasms - metabolism | CCN Intercellular Signaling Proteins - antagonists & inhibitors | Disease Models, Animal | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - pharmacology | Proto-Oncogene Proteins - antagonists & inhibitors | CCN Intercellular Signaling Proteins - pharmacology | Gene Expression | Radiation Tolerance - genetics | Proto-Oncogene Proteins - genetics | beta Catenin - metabolism | Protein Transport | Radiation Tolerance - drug effects | Xenograft Model Antitumor Assays | Animals | Esophageal Neoplasms - genetics | Tumor Burden - drug effects | CCN Intercellular Signaling Proteins - metabolism | Cell Line, Tumor | Mice | Care and treatment | Usage | Diagnosis | Radiotherapy | Esophageal cancer | Flow cytometry | Radiosensitivity | Toxicity | DNA damage | Radiation | Radioresistance | Transplantation | Kinases | Proteins | Cell cycle | Xenografts | Biocompatibility | Drug dosages | Deoxyribonucleic acid--DNA | Esophageal carcinoma | Cell survival | Radiation therapy | Tumor cell lines | Esophagus | Studies | Cytometry | Molecular modelling | Pulmonary fibrosis | Cell death | Medical prognosis | Irradiation | Immunofluorescence | Cancer | Apoptosis | Tumors | Deoxyribonucleic acid | DNA
Journal Article
International Immunopharmacology, ISSN 1567-5769, 10/2013, Volume 17, Issue 2, pp. 350 - 357
Journal Article
Journal of Cell Science, ISSN 0021-9533, 05/2011, Volume 124, Issue 10, pp. 1752 - 1758
During progression of breast cancer, CCN6 protein exerts tumor inhibitory functions. CCN6 is a secreted protein that modulates the insulin-like growth factor-1... 
Epithelial to mesenchymal transition | ZEB1 | CCN6 | WISP3 | IGF | Breast cancer | Insulin-like growth factor | CELLS | DELTA-EF1 | PROTEIN | E-CADHERIN | MIR-200 FAMILY | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | INSULIN | GROWTH | TRANSCRIPTIONAL REPRESSOR | Insulin-Like Growth Factor Binding Proteins - pharmacology | Receptor, IGF Type 1 - metabolism | Up-Regulation | Receptor, IGF Type 1 - antagonists & inhibitors | Homeodomain Proteins - metabolism | Humans | Epithelial-Mesenchymal Transition - drug effects | RNA, Messenger - metabolism | Breast Neoplasms - metabolism | Gene Knockdown Techniques | CCN Intercellular Signaling Proteins | Female | Insulin-Like Growth Factor Binding Proteins - genetics | Homeodomain Proteins - biosynthesis | Cell Dedifferentiation - drug effects | Down-Regulation | RNA, Messenger - genetics | Transcription Factors - biosynthesis | Recombinant Proteins - pharmacology | Transcription Factors - genetics | Homeodomain Proteins - genetics | Insulin-Like Growth Factor Binding Proteins - metabolism | Transcription Factors - metabolism | Signal Transduction - drug effects | Breast Neoplasms - pathology | Fluorescent Antibody Technique | Cell Line, Tumor | Insulin-Like Growth Factor Binding Proteins - deficiency | Insulin-Like Growth Factor I - metabolism | Zinc Finger E-box-Binding Homeobox 1
Journal Article
Journal Article
Journal Article