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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2019, Volume 520, Issue 2, pp. 385 - 391
Previous studies have shown that sarcopenic obesity is highly prevalent in patients with chronic kidney disease (CKD). Here, the association between CKD and... 
CCN1/Cyr61 | Sarcopenic obesity | Fibro/adipogenic progenitor | Adipogenic differentiation | Chronic kidney disease | Adipogenesis | Immunohistochemistry | Fluorescence | Models | Chronic kidney failure | Gene expression
Journal Article
by Su, RL and Qiao, Y and Guo, RF and Lv, YY
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, ISSN 1936-2625, 2019, Volume 12, Issue 9, pp. 3197 - 3207
Cyr61 (CCN1) is a multifunctional matricellular protein in bridging inflammation and cancer, involved in many biological functions such as tumorigenesis and... 
Cyr61/CCN1 | MMP11 | gastric cancer | proliferation | invasion | ONCOLOGY | NF-kB | CCN1/CYR61 | PATHOLOGY | CANCER | EXPRESSION
Journal Article
by Fan, Y and Zhao, J and Qian, J and Hao, Y and Wang, Q and Gao, L and Li, M and Zeng, X and Zhang, Z
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, ISSN 0392-856X, 07/2019, Volume 37, Issue 4, pp. 623 - 632
Objective This study aimed to evaluate the level of plasma Cysteine rich 61 (Cyr61) in systemic lupus erythematosus (SLE)-associated pulmonary arterial... 
SURVIVAL | systemic lupus erythematosus | CELL DISTRIBUTION WIDTH | INFLAMMATION | CCN1/CYR61 | MODEL | RHEUMATOLOGY | biomarker | pulmonary arterial hypertension | prognosis | cysteine-rich protein 61 | CYR61
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2017, Volume 36, Issue 16, pp. 2373 - 2389
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2018, Volume 505, Issue 4, pp. 966 - 972
Journal Article
The EMBO Journal, ISSN 0261-4189, 03/2007, Volume 26, Issue 5, pp. 1257 - 1267
Cytokines of the tumor necrosis factor (TNF) family regulate inflammation and immunity, and a subset of this family can also induce cell death in a... 
wound healing | CCN3 | CCN2 | NADPH oxidase | CTGF | Wound healing | FACTOR-RECEPTOR | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | JNK ACTIVATION | TUMOR-NECROSIS-FACTOR | PRO-ANGIOGENIC ACTIVITIES | HUMAN SKIN FIBROBLASTS | PROTEIN CCN1 CYR61 | ENDOTHELIAL-CELLS | EMBRYONIC LETHALITY | NF-KAPPA-B
Journal Article
Translational Oncology, ISSN 1936-5233, 03/2019, Volume 12, Issue 3, pp. 539 - 544
Since a fecal occult blood test for colorectal cancer (CRC) does not offer sufficient diagnostic power for CRC, novel non-invasive biomarkers are hopeful for... 
ONCOLOGY | MARKER | GROWTH | CCN1/CYR61 | RISK | PROLIFERATION | CCN1 | EXPRESSION | CARCINOMA | CYR61 SUPPRESSES
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 09/2015, Volume 309, Issue 7, pp. L747 - L748
Journal Article
FRONTIERS IN ONCOLOGY, ISSN 2234-943X, 10/2019, Volume 9
Background and Objective: Matricellular proteins modulate the micro environment of tumors and are recognized to contribute to tumor cell invasion and... 
CELLS | METASTASIS | breast cancer | EMT | CYR61 | IN-VITRO | invasion | ONCOLOGY | CCN1 CYR61 | triple negative breast cancer | S100A4 | PROGNOSTIC-SIGNIFICANCE | GROWTH-FACTOR | EXPRESSION | MOTILITY | Medicine, Experimental | Medical research | Breast cancer | Genetic aspects | Research | Stem cells
Journal Article
Cellular Signalling, ISSN 0898-6568, 01/2016, Volume 28, Issue 1, pp. 34 - 42
CCN1/CYR61 is a matricellular protein of the CCN family, comprising six secreted proteins specifically associated with the extracellular matrix (ECM). CCN1... 
ER stress | Hepatic stellate cells | Myofibroblasts | Matricellular protein | CCN1/CYR61 | Unfolded protein response | UNFOLDED-PROTEIN RESPONSE | LIVER FIBROSIS | MITOCHONDRIA | SIGNALS | INDUCTION | CELLULAR SENESCENCE | TAUROURSODEOXYCHOLIC ACID | CELL BIOLOGY | NUCLEUS | ENDOPLASMIC-RETICULUM | Liver diseases | RNA | Collagen | Liver | Apoptosis
Journal Article
by Liu, C and Cao, YL and He, X and Zhang, CY and Liu, J and Zhang, LL and Wu, DX and Zhuang, XD and Xue, RC and Huang, HL and Jiang, JZ and Dong, B and Sun, Y and Dong, YG and Zhao, JJ
BIOMARKERS IN MEDICINE, ISSN 1752-0363, 12/2019, Volume 13, Issue 18, pp. 1589 - 1597
Aim: The protein CCN1/CYR61 exerts critical functions in myocardial ischemic injury. We sought to investigate the prognostic value of CCN1 in patients with... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMEDIATE-EARLY GENE | FACTOR CCN1 | MUSCLE | ELEVATION | prognosis | CYR61 | Cyr61-cysteine-rich protein 61 | BIOMARKERS | ADHESION | TISSUE GROWTH-FACTOR | CCN1/CYR61 | coronary heart disease | acute heart failure | EXPRESSION | TROPONIN
Journal Article
Hepatology, ISSN 0270-9139, 01/2018, Volume 67, Issue 1, pp. 232 - 246
Journal Article
by Long, QZ and Zhou, M and Liu, XG and Du, YF and Fan, JH and Li, X and He, DL
ANTI-CANCER DRUGS, ISSN 0959-4973, 09/2013, Volume 24, Issue 8, pp. 810 - 817
Renal cell carcinoma (RCC) ranks among the most chemoresistant tumors, and P-glycoprotein (P-gp) predominates multidrug resistance mechanisms by reducing the... 
CANCER-CELLS | ACTIVATION | PROTEIN | DRUG-RESISTANCE | KAPPA-B | integrin alpha v beta 3 | PI3K/Akt | P-glycoprotein | renal cell carcinoma | ONCOLOGY | CCN1/CYR61 | PHARMACOLOGY & PHARMACY | AKT PATHWAY | CCN1 | MULTIDRUG-RESISTANCE | UP-REGULATION | EXPRESSION | vinblastine resistance
Journal Article