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Journal Article
Journal Article
Expert Opinion on Therapeutic Patents, ISSN 1354-3776, 03/2011, Volume 21, Issue 3, pp. 399 - 416
Introduction: The first US FDA approved HIV entry inhibitor drug Enfuvirdine belongs to the fusion inhibitor category. Earlier efforts in this area were... 
AIDS | CXCR4 | HIV | CCR5 | chemokine receptor | CHEMISTRY, MEDICINAL | HUMAN-IMMUNODEFICIENCY-VIRUS | CD4 | CONFORMATIONAL-CHANGES | GP41 CORE STRUCTURE | ENVELOPE | SYNTHETIC PEPTIDE | TARGETS | PHARMACOLOGY & PHARMACY | COILED-COIL | TYPE-1 | BINDING | Time Factors | HIV Fusion Inhibitors - pharmacology | Drug Discovery | Prodrugs - pharmacology | Patents as Topic
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 7/2007, Volume 196, Issue 2, pp. 304 - 312
Journal Article
Neurochemistry International, ISSN 0197-0186, 10/2018, Volume 119, pp. 184 - 189
Chemokine signaling is important in neuropathic pain, with microglial cells expressing chemokine (C-C motif) receptor CCR2, CCR5 and CCR8, all playing key... 
CCR5 | DAPTA | Chemotaxis | Chronic pain | Microglia | PEPTIDE-T DAPTA | CELLS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CCR2 ANTAGONISTS | DORSAL-ROOT GANGLION | NEUROSCIENCES | IN-VITRO EVIDENCE | RAT MODEL | CCL2 | CHEMOKINE RECEPTORS | ENTRY INHIBITOR | Care and treatment | Pain
Journal Article
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 05/2017, Volume 474, Issue 10, pp. 1559 - 1577
Infections by the human immunodeficiency virus type 1 (HIV-1), the causative agent of the acquired immunodeficiency syndrome (AIDS), are still totaling an... 
CCR5 ANTAGONIST | IN-VITRO | NONNUCLEOSIDE REVERSE-TRANSCRIPTASE | BOX RNA HELICASE | TREATMENT-EXPERIENCED SUBJECTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNODEFICIENCY-VIRUS TYPE-1 | PROTEASE INHIBITOR MONOTHERAPY | ANTIRETROVIRAL THERAPY | 4'-ETHYNYL-2-FLUORO-2'-DEOXYADENOSINE EFDA | SMALL-MOLECULE INHIBITOR | Anti-HIV Agents - pharmacology | CCR5 Receptor Antagonists - chemistry | CCR5 Receptor Antagonists - pharmacology | CCR5 Receptor Antagonists - therapeutic use | Humans | Antiretroviral Therapy, Highly Active - adverse effects | Reverse Transcriptase Inhibitors - pharmacology | Host-Pathogen Interactions - drug effects | Molecular Targeted Therapy | Reverse Transcriptase Inhibitors - chemistry | HIV Protease Inhibitors - pharmacology | Drug Therapy, Combination - adverse effects | HIV-1 - growth & development | HIV-1 - physiology | DEAD-box RNA Helicases - antagonists & inhibitors | Human Immunodeficiency Virus Proteins - chemistry | Drug Design | Anti-HIV Agents - therapeutic use | Molecular Structure | Reverse Transcriptase Inhibitors - therapeutic use | DEAD-box RNA Helicases - metabolism | DEAD-box RNA Helicases - chemistry | HIV Protease Inhibitors - adverse effects | Virus Replication - drug effects | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | HIV Infections - virology | HIV Protease Inhibitors - chemistry | Drug Resistance, Multiple, Viral | HIV-1 - genetics | HIV Protease Inhibitors - therapeutic use | Human Immunodeficiency Virus Proteins - metabolism | DEAD-box RNA Helicases - genetics | Anti-HIV Agents - chemistry | Animals | Models, Biological | Human Immunodeficiency Virus Proteins - antagonists & inhibitors | HIV Infections - drug therapy | Human Immunodeficiency Virus Proteins - genetics | Protein Conformation | Virus Physiological Phenomena - drug effects | Mutation | HIV Infections - metabolism
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 3/2009, Volume 48, Issue 6, pp. 798 - 805
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2013, Volume 33, Issue 4, pp. 718 - 726
OBJECTIVE—Macrophages are critical contributors to abdominal aortic aneurysm (AAA) disease. We examined the ability of MKEY, a peptide inhibitor of CXCL4–CCL5... 
chemokines | mice | CCL5 | abdominal aortic aneurysm | CXCL4 | ATHEROSCLEROTIC LESIONS | PROGENITOR CELLS | RECRUITMENT | WALL | RECEPTOR CCR2 | RANTES | BONE-MARROW | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | INFUSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | E-DEFICIENT MICE | Aortic Aneurysm, Abdominal - chemically induced | Aortic Aneurysm, Abdominal - prevention & control | Injections, Intravenous | Aortic Aneurysm, Abdominal - immunology | Apolipoproteins E - deficiency | Male | Aorta, Abdominal - drug effects | Chemokine CCL5 - antagonists & inhibitors | Aortic Aneurysm, Abdominal - metabolism | Leukocytes - immunology | Matrix Metalloproteinase 9 - metabolism | Receptors, CCR5 - metabolism | Chemotaxis, Leukocyte - drug effects | Time Factors | Chemokine CCL5 - metabolism | Aorta, Abdominal - pathology | Angiotensin II | Myocytes, Smooth Muscle - drug effects | Aorta, Abdominal - metabolism | Aortic Aneurysm, Abdominal - pathology | Macrophages - immunology | Disease Models, Animal | Matrix Metalloproteinase 2 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Aortic Aneurysm, Abdominal - genetics | Platelet Factor 4 - antagonists & inhibitors | Disease Progression | Mice, Knockout | Aorta, Abdominal - immunology | Animals | Apolipoproteins E - genetics | Myocytes, Smooth Muscle - immunology | Pancreatic Elastase | Leukocytes - drug effects | Macrophages - drug effects | Mice | Oligopeptides - administration & dosage | Platelet Factor 4 - metabolism | Oligopeptides - pharmacology
Journal Article