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Journal of Hainan Medical University, ISSN 1007-1237, 09/2016, Volume 22, Issue 18, pp. 102 - 105
Objective: To invest the clinical significance of serum SCC-Ag combined with CD105 in early diagnosis of cervical cancer to provide new ideas for early... 
the difference was statistically significant. Comparing with Ⅰ period of TMN staging | SCC-Ag and CD105 were positively correlated. Conclusion: SCC-Ag and CD105 in patients with cervical cancer increase highly | and to compare SCC-Ag and CD105 in different TMN staging | SCC-Ag and CD105 were checked by ELISA method | period increased | comparing with normal cervical group | the SCC-Ag and CD105 of cervical cancer group increased | SCC-Ag and CD105 of | SCC-Ag | SCC-Ag and CD105 of Ⅱ period increased | especially it has clinical guiding significance to staging and lymph gland metastasis of cervical cancer | and 52 cases uterine fibroids patients were selected as normal cervical group | Early stage diagnosis | the difference was statistically significant. Comparing with non-lymph gland metastasis | lymph gland metastasis and non-lymph gland metastasis in patients with cervical cancer | SCC-Ag and CD105 of two groups were analyzed by t-test | the difference was statistically significant. Comparing with Ⅱ period | serum samples were collected in the early morning fasting condition | the difference was statistically significant. According to Pearson correlation analysis | Clinical significance | it has important clinical value that of serum SCCAg combined with CD105 in the early diagnosis of cervical cancer | the correlation analysis was used by Pearson correlation analysis method. Results: These results came from ELISA method | CD105 | SCC-Ag and CD105 of lymph gland metastasis increased in cervical cancer with surgical treatment | Cervical cancer
Journal Article
BIOMATERIALS, ISSN 0142-9612, 06/2012, Volume 33, Issue 16, pp. 4147 - 4156
The goal of this study was to employ nano-graphene for tumor targeting in an animal tumor model, and quantitatively evaluate the pharmacokinetics and tumor... 
Molecular imaging | Positron emission tomography (PET) | MATERIALS SCIENCE, BIOMATERIALS | OXIDE | ENGINEERING, BIOMEDICAL | Ga-66 | CD105 (endoglin) | Tumor angiogenesis | ANTIBODY | CANCER | QUANTUM DOTS | THERAPY | Graphene | PET | ENDOTHELIAL GROWTH-FACTOR | ENDOGLIN CD105
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 07/2018, Volume 15, Issue 7, pp. 2606 - 2613
Angiogenesis is widely recognized as one of the hallmarks of cancer. Therefore, imaging and therapeutic agents targeted to angiogenic vessels may be widely... 
radioimmunotherapy | yttrium-86 | positron emission tomography (PET) | angiogenesis | theranostics | cancer | yttrium-90 | CD105/endoglin | CD105 | endoglin
Journal Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, ISSN 1619-7070, 05/2013, Volume 40, Issue 5, pp. 759 - 767
The goal of this study was to generate and characterize the Fab fragment of TRC105, a monoclonal antibody that binds with high affinity to human and murine... 
Positron emission tomography (PET) | SOLID TUMORS | Fab | Tumor angiogenesis | MONOCLONAL-ANTIBODY | CANCER | Cu-61 | Antibody fragment | POSITRON-EMISSION-TOMOGRAPHY | VASCULATURE | I-131-LABELED F(AB') | MICE | CD105(endoglin) | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CD105 EXPRESSION | Cu-64 | ENDOGLIN CD105
Journal Article
BMC cancer, ISSN 1471-2407, 01/2018, Volume 18, Issue 1, pp. 31 - 11
Background: The Intratumoral Microvessel Density (IMVD) is commonly used to quantify tumoral vascularization and is usually assessed by pan-endothelial... 
CD105/CD31 ratio | Endoglin (CD105) | Prognostic marker | Rhabdomyosarcoma | VASCULOGENIC MIMICRY | BREAST-CARCINOMA | ANGIOGENESIS | TISSUE | TUMOR | ANTIBODY | MICROVESSEL DENSITY | ALVEOLAR | PROGNOSTIC-FACTOR | ONCOLOGY | ENDOTHELIAL GROWTH-FACTOR | Glycoproteins | Research | Neovascularization | Tumor staging | Analysis
Journal Article
Biomaterials, ISSN 0142-9612, 06/2012, Volume 33, Issue 16, pp. 4147 - 4156
The goal of this study was to employ nano-graphene for tumor targeting in an animal tumor model, and quantitatively evaluate the pharmacokinetics and tumor... 
Molecular imaging | Tumor angiogenesis | Positron emission tomography (PET) | 66Ga | Graphene | CD105 (endoglin) | molecular imaging | positron emission tomography (PET) | tumor angiogenesis
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 11/2018, Volume 19, Issue 11, pp. 1006 - 1014
Objectives: The study was designed to investigate the tumor vessel-associated CD105 expression in monocytes from tumor tissue and peripheral blood (PB) in... 
sunitinib | CD105 | immunohistochemistry | hepatocellular carcinoma | real-time quantitative PCR | CHEMOEMBOLIZATION | CANCER CELLS | ONCOLOGY | GROWTH | ENDOGLIN CD105 | BETA
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2017, Volume 23, Issue 16, pp. 4633 - 4641
Purpose: Endoglin (CD105) is an endothelial cell membrane receptor highly expressed on proliferating tumor vasculature, including that of hepatocellular... 
ADVANCED CANCER | ANGIOGENESIS | ONCOLOGY | ANTI-ENDOGLIN ANTIBODY | BEVACIZUMAB | CD105
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2012, Volume 18, Issue 3, pp. 869 - 881
Purpose: Within heterogeneous tumors, subpopulations often labeled cancer stem cells (CSC) have been identified that have enhanced tumorigenicity and... 
ONCOLOGY | ALDEHYDE DEHYDROGENASE | THERAPEUTIC TARGET | ANTIBODY | DEFINES | DRUG-RESISTANCE | GROWTH-FACTOR | EXPRESSION | CARCINOMA | HEDGEHOG | ENDOGLIN CD105 | Immunohistochemistry | Adenocarcinoma - pathology | Aldehyde Dehydrogenase - analysis | Antigens, CD - biosynthesis | Humans | Zinc Finger Protein Gli2 | Aldehyde Dehydrogenase - biosynthesis | Ovarian Neoplasms - pathology | Laser Capture Microdissection | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Antigens, CD - genetics | Antigens, CD - analysis | Ovarian Neoplasms - genetics | Endoglin | Adenocarcinoma - metabolism | Neoplastic Stem Cells - metabolism | Nuclear Proteins - biosynthesis | Neoplastic Stem Cells - pathology | Female | Adenocarcinoma - genetics | Ovarian Neoplasms - metabolism | Receptors, Cell Surface - biosynthesis | Nuclear Proteins - genetics | Kruppel-Like Transcription Factors - biosynthesis | Neoplasm Recurrence, Local - metabolism | Hyaluronan Receptors - biosynthesis | Reverse Transcriptase Polymerase Chain Reaction | AC133 Antigen | Blotting, Western | Glycoproteins - biosynthesis | Hyaluronan Receptors - analysis | Signal Transduction - physiology | Glycoproteins - analysis | Drug Resistance, Neoplasm - physiology | Kruppel-Like Transcription Factors - genetics | Peptides - analysis | Receptors, Cell Surface - genetics | aldehyde dehydrogenase | cancer stem cell | ovarian cancer | ALDH1A1 | CD105 | endoglin | gli1 | CD44 | gli2 | CD133
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 7/2011, Volume 38, Issue 7, pp. 1335 - 1343
Journal Article
PLoS ONE, 11/2013, Volume 8, Issue 11
Background The goal of this study was to explore the feasibility of utilizing human umbilical mesenchymal stem cells (HUMSCs)-seeded Bladder acellular matrix... 
CD105 antigen
Journal Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, ISSN 1619-7070, 01/2012, Volume 39, Issue 1, pp. 138 - 148
Journal Article
by Wang, H and Xie, J
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, ISSN 1936-2625, 2018, Volume 11, Issue 5, pp. 2805 - 2810
Objective: SOX2 belongs to the SOX gene family of high-mobility transcription factors indispensably involved in gene regulation in pluripotent stern cells and... 
SOX2 | TARGET | CELLS | THERAPY | ONCOLOGY | MARKER | angiogenesis | SEQUENCE | breast cancer | CD105 | PATHOLOGY | ENDOGLIN CD105
Journal Article
PLOS ONE, ISSN 1932-6203, 12/2011, Volume 6, Issue 12
Optimizing the in vivo stability of positron emission tomography (PET) tracers is of critical importance to cancer diagnosis. In the case of Cu-64-labeled... 
THERAPY | SOLID TUMORS | RADIOPHARMACEUTICALS | VASCULATURE | COMPLEXES | STABILITIES | BIOLOGY | BEARING MICE | CANCER | PET | ENDOGLIN CD105
Journal Article
Current Cancer Drug Targets, ISSN 1568-0096, 12/2009, Volume 9, Issue 8, pp. 982 - 1004
The requirements for a cell surface molecule to be suitable as an antibody-drug conjugate target are stringent. The notion that antibodies-directed toward... 
CD105 MONOCLONAL-ANTIBODIES | HUMAN ENDOGLIN CD105 | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | REGULATORY T-CELLS | ENGINEERED ANTI-CD70 ANTIBODY | FIBROBLAST ACTIVATION PROTEIN | MULTIPLE-MYELOMA CELLS | RENAL-CELL CARCINOMA | SITE-SPECIFIC CONJUGATION | ED-B FIBRONECTIN
Journal Article
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