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1. T cell activation by CD1 and lipid antigens
by Moody, D. Branch
2007, Current topics in microbiology and immunology, ISBN 3540695109, Volume 314., vi, 345
There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse... 
CD antigens | T cells | Receptors | Immunology | Biomedicine
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2. Full Text Switched CD21–/low B cells with an antigen-presenting phenotype in the infant thymus
by Lundqvist, Christina and Camponeschi, Alessandro and Visentini, Marcella and Telemo, Esbjörn and Ekwall, Olov and Mårtensson, Inga-Lill
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 04/2019, Volume 143, Issue 4, pp. 1616 - 1620.e7
[...]a few of the switched thymic B cells were positive for IgE or IgG4 (Fig E1, H), which suggests that all immunoglobulin isotypes are present on the thymic... 
CD27 antigen | Immunoglobulin M | Heart | Cytokeratin | Flow cytometry | CD40 antigen | CD86 antigen | Immunoglobulin G | Antibodies | Immunoglobulin E | Confocal microscopy | Lymphocytes T | Immunoglobulin D | Kinases | Immunoglobulin A | Thymus | CD69 antigen | Demographics | Surgery | CD38 antigen | CD25 antigen | Chromosomes | CD34 antigen | CD11c antigen | Antigens | Phenotypes | Immunoglobulins | CD19 antigen | CD95 antigen | CD3 antigen | CXCR3 protein | Dilution | Lymphocytes B | Microscopy | Antigen-presenting cells
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3. Full Text AB0014 Differential effects of a single dose of cyclophosphamide on circulating cell subpopulations in patients with vasculitides and autoimmune systemic diseases
by Gabcova, G and Mikulkova, Z and Skacelova, M and Petrackova, A and Smrzova, A and Schubertova, M and Mrazek, F and Horak, P and Kriegova, E
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 1051
BackgroundHigh-dose cyclophosphamide (CFA) is used for treatment of patients with severe manifestations of systemic autoimmune diseases. The knowledge about... 
CD27 antigen | Systemic diseases | CD8 antigen | Lymphocytes T | CD14 antigen | Immunoglobulin A | CD69 antigen | Cell activation | Lymphocytes | CD25 antigen | Natural killer cells | CD56 antigen | CD11b antigen | Statistical analysis | CD19 antigen | Neutrophils | CD62L protein | Leukocytes (neutrophilic) | CD3 antigen | Patients | CD4 antigen | Monocytes | Cyclophosphamide | CD16 antigen | Lymphocytes B | CD20 antigen | Histocompatibility antigen HLA | Autoimmune diseases
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4. Full Text Mucosal-Associated invariant T Cell Is a potential marker to distinguish fibromyalgia syndrome from arthritis
by Sugimoto, Chie and Konno, Takahiko and Wakao, Rika and Fujita, Hiroko and Fujita, Hiroyoshi and Wakao, Hiroshi
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, pp. e0121124 - e0121124
Background Fibromyalgia (FM) is defined as a widely distributed pain. While many rheumatologists and pain physicians have considered it to be a pain disorder,... 
DIAGNOSIS | CYTOKINES | ANKYLOSING-SPONDYLITIS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | Diagnosis, Differential | Fibromyalgia - metabolism | Cell Count | Humans | Middle Aged | Gene Expression Regulation | Male | Fibromyalgia - blood | Biomarkers - blood | Fibromyalgia - diagnosis | Spondylarthritis - diagnosis | T-Lymphocytes - metabolism | Fibromyalgia - immunology | Antigens, Surface - metabolism | Female | T-Lymphocytes - immunology | T-Lymphocytes - pathology | Arthritis, Rheumatoid - diagnosis | Physiological aspects | Fibromyalgia | Arthritis | Research | Diagnosis | T cells | CD27 antigen | CC chemokine receptors | Flow cytometry | CD26 antigen | Physicians | Psychology | Mucosa | Fluorescence | Lymphocytes T | CD28 antigen | Cell surface | Blood | Invariants | Inflammatory diseases | Interleukin 7 | CD69 antigen | Receptors | Dipeptidase | Pain | CD44 antigen | Bioindicators | Natural killer cells | Medical personnel | Antigens | CCR5 protein | CD49d antigen | CCR7 protein | Inflammation | CD150 antigen | Patients | Chemokine receptors | CXCR4 protein | Signaling | Rheumatoid arthritis | ICOS protein | Biomarkers | Diagnostic systems | Psychiatry | Index Medicus
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5. Full Text Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
by Fraietta, Joseph A and Lacey, Simon F and Orlando, Elena J and Pruteanu-Malinici, Iulian and Gohil, Mercy and Lundh, Stefan and Boesteanu, Alina C and Wang, Yan and O'connor, Roddy S and Hwang, Wei-Ting and Pequignot, Edward and Ambrose, David E and Zhang, Changfeng and Wilcox, Nicholas and Bedoya, Felipe and Dorfmeier, Corin and Chen, Fang and Tian, Lifeng and Parakandi, Harit and Gupta, Minnal and Young, Regina M and Johnson, F. Brad and Kulikovskaya, Irina and Liu, Li and Xu, Jun and Kassim, Sadik H and Davis, Megan M and Levine, Bruce L and Frey, Noelle V and Siegel, Donald L and Huang, Alexander C and Wherry, E. John and Bitter, Hans and Brogdon, Jennifer L and Porter, David L and June, Carl H and Melenhorst, J. Joseph
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 5, pp. 563 - 571
Tolerance to self-antigens prevents the elimination of cancer by the immune system(1,2). We used synthetic chimeric antigen receptors (CARs) to overcome... 
MEDICINE, RESEARCH & EXPERIMENTAL | EXPRESSION ANALYSIS | EFFICACY | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFECTOR FUNCTION | SUBSETS | IDENTIFICATION | CELL BIOLOGY | B-CELL | GENE | TELOMERASE ACTIVITY | PD-1 | EXHAUSTION | Chronic lymphocytic leukemia | Care and treatment | Antigen receptors, T cell | Receptors | Immunotherapy | Cellular therapy | Physiological aspects | Development and progression | T cells | Health aspects | Methods | CD27 antigen | Cell proliferation | PD-1 protein | CD8 antigen | Leukemia | Lymphocytes T | Interleukin 6 | Immunology | Lymphocytes | Interleukin 6 receptors | Remission | Bioindicators | Pretreatment | Antigens | Memory cells | Chronic lymphatic leukemia | CD19 antigen | Cytokines | Stat3 protein | Autoantigens | Lymphatic leukemia | Patients | Immunological tolerance | Exhaustion | Biomarkers | Glycolysis | Determinants | Cancer | Tumors | Apoptosis | Index Medicus
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6. Full Text Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity
by Chang, Yu-Han and Wang, Kuan Chung and Chu, Kuan-Lun and Clouthier, Derek L and Tran, Anh T and Torres Perez, Miguel S and Zhou, Angela C and Abdul-Sater, Ali A and Watts, Tania H
Immunity, ISSN 1074-7613, 11/2017, Volume 47, Issue 5, pp. 943 - 958.e9
T cell antigen-presenting cell (APC) interactions early during chronic viral infection are crucial for determining viral set point and disease outcome, but how... 
type I interferon | monocyte-derived inflammatory APC | viral infection | costimulation | B7 family | lymphocytic choriomeningitis virus | TNF family | influenza A virus | PLASMACYTOID DENDRITIC CELLS | RESPONSES | B-LYMPHOCYTE | HERPESVIRUS ENTRY MEDIATOR | PERSISTENT LCMV INFECTION | CO-STIMULATION | LYMPHOCYTE ATTENUATOR | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | GITR LIGAND | I INTERFERON | Membrane Glycoproteins - analysis | Monocytes - cytology | Dendritic Cells - immunology | Mice, Inbred C57BL | Glucocorticoid-Induced TNFR-Related Protein - analysis | Lymphocytic Choriomeningitis - immunology | Antigen-Presenting Cells - immunology | Tumor Necrosis Factors - analysis | CX3C Chemokine Receptor 1 - analysis | CD4-Positive T-Lymphocytes - immunology | Glucocorticoid-Induced TNFR-Related Protein - physiology | Animals | Female | Mice | CD27 Ligand - analysis | Tumor necrosis factor receptors | CD86 antigen | Chronic infection | Viruses | CX3CR1 protein | Infections | Lymphocytes T | CD70 antigen | Immunity | Accumulation | Lymphocytes | CD25 antigen | Tumor necrosis factor-TNF | Immune system | Antiviral agents | Antigens | Dendritic cells | Priming | CD80 antigen | T cell receptors | CD4 antigen | Monocytes | Ox40L protein | Tumor necrosis factor | Antigen-presenting cells | Ligands | Interferon | Viral infections | Division of labor | Index Medicus
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7. Full Text Accumulation of Antigen‐Driven Lymphoproliferations in Complement Receptor 2/CD21−/low B Cells From Patients With Sjögren's Syndrome
by Glauzy, Salomé and Boccitto, Marco and Bannock, Jason M and Delmotte, Fabien R and Saadoun, David and Cacoub, Patrice and Ice, John A and Sivils, Kathy L and James, Judith A and Wolin, Sandra L and Meffre, Eric
Arthritis & Rheumatology, ISSN 2326-5191, 02/2018, Volume 70, Issue 2, pp. 298 - 307
Patients with Sjögren's syndrome (SS) are prone to develop malignant lymphomas, and a correlation has been established between the lymphoproliferations... 
CD27 antigen | Immunoglobulin M | Lymphocyte receptors | Antigens | Sjogren's syndrome | CD19 antigen | Complement receptor 2 | Antibodies | Autoantigens | T cell receptors | B-cell receptor | Patients | Blood | Polymerase chain reaction | Receptors | Somatic hypermutation | Lymphocytes B | Peripheral blood | Recombinant | Index Medicus | Abridged Index Medicus
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8. Full Text Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+IgD+CD27+ B cell repertoire in infants
by Weller, Sandra and Mamani-Matsuda, Maria and Picard, Capucine and Cordier, Corinne and Lecoeuche, Damiana and Gauthier, Frédéric and Weill, Jean-Claude and Reynaud, Claude-Agnès
Journal of Experimental Medicine, ISSN 0022-1007, 06/2008, Volume 205, Issue 6, pp. 1331 - 1342
T cell-dependent immune responses develop soon after birth, whereas it takes 2 yr for humans to develop T cell-independent responses. We used this dissociation... 
MEDICINE, RESEARCH & EXPERIMENTAL | SPLENIC MARGINAL ZONE | POSITIVE SELECTION | HYPER-IGM SYNDROME | INDUCED CYTIDINE DEAMINASE | IMMUNOGLOBULIN GENES | V-H GENES | COMMON VARIABLE IMMUNODEFICIENCY | CLASS-SWITCH RECOMBINATION | PERIPHERAL-BLOOD | GERMINAL-CENTERS | IMMUNOLOGY | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | Antigens, CD - immunology | Spleen - immunology | Immunoglobulin mu-Chains - immunology | Lymphocyte Activation | Humans | Infant | Immunoglobulin M - immunology | Immunoglobulin D - immunology | Genetic Variation | B-Lymphocytes - immunology | Gene Rearrangement | B-Lymphocyte Subsets - immunology | Immunoglobulin Variable Region - genetics | Immunologic Memory | T-Lymphocytes - immunology | Transcription, Genetic | Index Medicus | Spleen | Immunoglobulin M | Antigens, CD27 | T-Lymphocytes | B-Lymphocytes | Immunoglobulin D | Variation (Genetics) | Life Sciences | B-Lymphocyte Subsets | Immunology | Immunoglobulin mu-Chains | Immunoglobulin Variable Region | Antigens, CD
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9. Full Text OC40 Is down syndrome related arthritis (DA) a distinct disease from juvenile idiopathic arthritis (JIA)?
by Foley, Charlene and Killeen, Orla and MacDermott, Emma and Wilson, Gerry and Floudas, Achilleas and Fearon, Ursula
Archives of Disease in Childhood, ISSN 0003-9888, 06/2019, Volume 104, Issue Suppl 3, p. A17
DA is frequently polyarticular-RF-negative with predominance in the small joints of the hands and wrists. It has an erosive phenotype, and clinically appears... 
CD27 antigen | Immunoglobulin M | Flow cytometry | Pediatrics | CD40 antigen | CD86 antigen | Pathogenesis | CD8 antigen | Hyperplasia | Childrens health | Lymphocytes T | Arthritis | Immunoglobulin D | CD45 antigen | Down's syndrome | CD38 antigen | Children | Phenotypes | Immunological memory | CD19 antigen | Granulocyte-macrophage colony-stimulating factor | CD80 antigen | CD3 antigen | Down syndrome | Joint diseases | Quality of life | Lymphocytes B | Biopsy | CD20 antigen
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10. Full Text Skin resident memory CD8+ T cells are phenotypically and functionally distinct from circulating populations and lack immediate cytotoxic function
by Seidel, J. A and Vukmanovic‐Stejic, M and Muller‐Durovic, B and Patel, N and Fuentes‐Duculan, J and Henson, S. M and Krueger, J. G and Rustin, M. H. A and Nestle, F. O and Lacy, K. E and Akbar, A. N
Clinical & Experimental Immunology, ISSN 0009-9104, 10/2018, Volume 194, Issue 1, pp. 79 - 92
The in‐depth understanding of skin resident memory CD8 + T lymphocytes (T RM ) may help to uncover strategies for their manipulation during disease. We... 
skin | regulation | T cells | cytotoxicity | TELOMERE EROSION | SUBSETS | PERFORIN | PROLIFERATION | IMMUNOLOGY | MAINTENANCE | IN-VIVO | INFECTION | EXPRESSION | GRANZYME-B | ANTIGEN | Skin - cytology | Leukocyte Common Antigens - metabolism | Granzymes - metabolism | Humans | Middle Aged | Male | Interleukin-15 - immunology | Antigens, CD - metabolism | Young Adult | Lectins, C-Type - metabolism | Interleukin-2 - immunology | Tumor Necrosis Factor-alpha - immunology | Aged, 80 and over | Adult | Female | CD57 Antigens - metabolism | Immunologic Memory - immunology | Skin - immunology | T-Lymphocytes, Cytotoxic - immunology | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | CD28 Antigens - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism | Trans-Activators - metabolism | Aged | Perforin - metabolism | Telomeres | Killer cells | Interleukins | Cell death | Lectins | Skin | CD57 antigen | CD27 antigen | Populations | CD8 antigen | CD45RA antigen | Interleukin | Cytotoxicity | Lymphocytes T | CD28 antigen | T-cell receptor | CD69 antigen | Receptors | Cell activation | Granzyme B | Lymphocytes | Tumor necrosis factor-TNF | Perforin | Immunological memory | Memory cells | T cell receptors | KLRG1 protein | Tumor necrosis factor | Tumors | Apoptosis
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11. Full Text Recovery of circulating CD56^sup dim^ NK cells and the balance of Th17/Treg after nucleoside analog therapy in patients with chronic hepatitis B and low levels of HBsAg
by Nianqiu Liu and Bin Liu and Li Zhang and Hu Li and Zhiwei Chen and Aoran Luo and Min Chen and Mingli Peng and Wenwei Yin and Hong Ren and Peng Hu
International Immunopharmacology, ISSN 1567-5769, 09/2018, Volume 62, p. 59
Background and aims Much evidence indicates that the soluble antigens secreted by hepatitis B virus (HBV) inhibit the function of the immune system. The aim of... 
CD27 antigen | Flow cytometry | Adaptive systems | CD40 antigen | CD8 antigen | Helper cells | Viruses | Lymphocytes T | CD40L protein | Hepatitis | CTLA-4 protein | CXCR5 protein | Lymphocytes | CD38 antigen | CD25 antigen | Inhibition | Hepatitis B virus | CD56 antigen | Deoxyribonucleic acid--DNA | Immune system | Antigens | Phenotypes | Alanine | CD19 antigen | Dendritic cells | Patients | Cells | CD4 antigen | Immune systems | Hepatitis B e antigen | Lymphocytes B | Alanine transaminase | Nucleosides | Replication | Aspartate aminotransferase
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12. Full Text Preclinical evaluation of TriMix and antigen mRNA-based antitumor therapy
by Van Lint, Sandra and Goyvaerts, Cleo and Maenhout, Sarah and Goethals, Lode and Disy, Aurélie and Benteyn, Daphné and Pen, Joeri and Bonehill, Aude and Heirman, Carlo and Breckpot, Karine and Thielemans, Kris
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 7, pp. 1661 - 1671
The use of tumor-associated antigen (TAA) mRNA for therapeutic purposes is under active investigation. To be effective, mRNA vaccines need to deliver... 
PATHWAYS | ELECTROPORATED DENDRITIC CELLS | ACTIVATION | ONCOLOGY | IN-VIVO | TOLL-LIKE RECEPTORS | VACCINATION | CANCER-IMMUNOTHERAPY | INDUCTION | LIGAND | GENETIC-MODIFICATION | Amino Acid Sequence | Antigens, Neoplasm - genetics | RNA, Messenger - immunology | Lymphocyte Activation | Dendritic Cells - immunology | Mice, Inbred C57BL | Vaccination | Neoplasms, Experimental - therapy | CD27 Ligand - genetics | Molecular Sequence Data | Toll-Like Receptor 4 - genetics | CD11c Antigen - analysis | RNA, Messenger - pharmacokinetics | Animals | CD40 Ligand - genetics | Neoplasms, Experimental - immunology | Female | Mice, Inbred DBA | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Electrochemotherapy | CD11c antigen | Animal models | Translation | CD40 antigen | Dendritic cells | CD8 antigen | Therapeutic applications | Cytotoxicity | Lymphocytes T | TLR4 protein | Vaccines | CD70 antigen | Lymph nodes | CD4 antigen | Cell activation | Antigen (tumor-associated) | Toll-like receptors | Cancer | Tumors | Index Medicus
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13. Full Text Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8+ T Cells
by Ballesteros-Tato, André and León, Beatriz and Lee, Byung O and Lund, Frances E and Randall, Troy D
Immunity, ISSN 1074-7613, 07/2014, Volume 41, Issue 1, pp. 127 - 140
Memory CD8 T cells are programmed during the primary response for robust secondary responsiveness. Here we show that CD8 T cells responding to different... 
IMMUNODOMINANCE | EFFECTOR | RESPONSES | VIRUS-INFECTION | DENDRITIC CELLS | CD8-T-CELL MEMORY | CD4-T-CELL HELP | CD40 LIGAND | IMMUNOLOGY | VIRAL-INFECTION | CROSS-PRESENTATION | Antigens, CD - immunology | CD40 Antigens - antagonists & inhibitors | Minor Histocompatibility Antigens | Dendritic Cells - immunology | Interleukin-2 Receptor alpha Subunit - biosynthesis | Adoptive Transfer | Signal Transduction - immunology | Lymphocyte Activation - immunology | Interleukin-2 - immunology | Interleukin-2 Receptor alpha Subunit - genetics | Integrin alpha Chains - immunology | Influenza A virus - immunology | CD40 Antigens - genetics | Histocompatibility Antigens Class I - pharmacology | Epitopes, T-Lymphocyte - immunology | Immunologic Memory - immunology | Nucleoproteins - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | CD11b Antigen - immunology | CD27 Ligand - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | DNA-Directed RNA Polymerases - immunology | Mice, Transgenic | Antigen Presentation - immunology | Animals | Viral Core Proteins - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | CD40 Antigens - immunology | Interferon-gamma - biosynthesis | Orthomyxoviridae Infections - immunology | Flow cytometry | Antigens | Lymphocytes | Ligands | T cell receptors | Infections | Experiments | Immune system | Index Medicus
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14. Full Text FRI0001 Extended oligoarticular and polyarticular juvenile idiopathic arthritis patients have a similar b cell phenotype when compared to established rheumatoid arthritis
by Moura, R.A and Brito, A and Oliveira, S and Teixeira, R.L and Romão, V.C and Teixeira, V and Campanilho-Marques, R and Oliveira-Ramos, F and Fonseca, J.E
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2018, Volume 77, Issue Suppl 2, p. 548
BackgroundOur group has recently described that the majority of polyarticular juvenile idiopathic arthritis (pJIA) and a large fraction of extended... 
CD27 antigen | Cell culture | Flow cytometry | CD40 antigen | CD86 antigen | Pathogenesis | Immunoglobulin D | Genotype & phenotype | Cell activation | CD23 antigen | CXCR5 protein | CD38 antigen | Peripheral blood | Children | Methotrexate | Immune system | Immunological memory | Memory cells | Phenotypes | CD19 antigen | CD95 antigen | CD5 antigen | Lymphocytes B | Cell death | BLyS protein | Rheumatoid arthritis | Histocompatibility antigen HLA | Apoptosis
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15. Full Text Preclinical evaluation of chimeric antigen receptors targeting CD70-expressing cancers
by Wang, Qiong J and Yu, Zhiya and Hanada, Ken-Ichi and Patel, Krishna and Kleiner, David and Restifo, Nicholas P and Yang, James C
Clinical Cancer Research, ISSN 1078-0432, 05/2017, Volume 23, Issue 9, pp. 2267 - 2276
Purpose: CD70 expression in normal tissues is restricted to activated lymphoid tissues. Targeting CD70 on CD70-expressing tumors could mediate "on-target,... 
REGRESSION | ONCOLOGY | CD70 | IN-VIVO PERSISTENCE | CD27 | GENE-THERAPY | ANTITUMOR-ACTIVITY | EXPRESSION | RENAL-CELL CARCINOMA | T-CELLS | LYMPHOCYTES | CD27 Ligand - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | Immunotherapy, Adoptive | Humans | CD27 Ligand - genetics | CD28 Antigens - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - genetics | Xenograft Model Antitumor Assays | Signal Transduction - immunology | Neoplasms - therapy | Animals | CD3 Complex - genetics | CD28 Antigens - genetics | Neoplasms - genetics | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Neoplasms - immunology | CD3 Complex - immunology | Cell Line, Tumor | Receptors, Antigen, T-Cell - administration & dosage | Receptors, Antigen, T-Cell - immunology | Mice | Receptors, Antigen, T-Cell - genetics | CD27 antigen | Toxicity | Fuel consumption | Feasibility analysis | Homology | CD70 antigen | CD28 antigen | Receptors | Lymphocytes | Splenocytes | Safety engineering | Animal tissues | Xenografts | Biocompatibility | Safety | Binding | Immune response | Effectiveness | Feasibility studies | CD3 antigen | Lymphoid tissue | Experimental design | γ-Interferon | In vivo methods and tests | Tumors | Cancer | Index Medicus
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