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The Journal of Immunology, ISSN 0022-1767, 04/2004, Volume 172, Issue 7, pp. 4100 - 4110
Human monocyte-derived dendritic cells (DCs) are capable of expressing the tryptophan-degrading enzyme indoleamine 2,3-dioxygenase (IDO), which allows them to... 
RESPONSES | SERUM-FREE CONDITIONS | INHIBITION | KILLER-CELL | MECHANISM | SUBSETS | ANTIGEN-PRESENTING CELLS | PROLIFERATION | IMMUNOLOGY | INDUCE TOLERANCE | TRYPTOPHAN CATABOLISM | Antigens, CD - immunology | Tryptophan Oxygenase - antagonists & inhibitors | Membrane Glycoproteins - metabolism | T-Lymphocyte Subsets - cytology | Antigens, CD - biosynthesis | Dendritic Cells - immunology | Humans | Membrane Glycoproteins - biosynthesis | Antibodies, Blocking - pharmacology | CD4-Positive T-Lymphocytes - enzymology | Enzyme Induction - immunology | Tryptophan - metabolism | Enzyme Activation - immunology | Tryptophan Oxygenase - physiology | Antigens, CD - metabolism | Lymphocyte Culture Test, Mixed | CD4-Positive T-Lymphocytes - immunology | Immunoconjugates - immunology | B7-2 Antigen | Membrane Glycoproteins - physiology | Tryptophan Oxygenase - biosynthesis | Flow Cytometry | Abatacept | Immunosuppressive Agents - metabolism | B7-1 Antigen - biosynthesis | Membrane Glycoproteins - immunology | B7-1 Antigen - immunology | CD4-Positive T-Lymphocytes - cytology | Cells, Cultured | B7-1 Antigen - physiology | Interferon-gamma - physiology | B7-1 Antigen - metabolism | CD28 Antigens - immunology | Growth Inhibitors - metabolism | Tryptophan Oxygenase - metabolism | Up-Regulation - immunology | Dendritic Cells - enzymology | Down-Regulation - immunology | T-Lymphocyte Subsets - enzymology | Growth Inhibitors - physiology | Antigens, CD - physiology | Ligands | Indoleamine-Pyrrole 2,3,-Dioxygenase | Index Medicus | Abridged Index Medicus
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 01/2004, Volume 172, Issue 1, pp. 104 - 113
Chimeric receptors that include CD28 signaling in series with TCRzeta in the same receptor have been demonstrated to activate prestimulated human primary T... 
RESPONSES | 4-1BB LIGAND | CYTOKINE PRODUCTION | IN-VIVO | FACTOR-KAPPA-B | MOLECULAR-CLONING | ANTITUMOR IMMUNITY | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | ICOS | EXPRESSION | Mutagenesis, Insertional - methods | Humans | Interphase - immunology | Receptors, Tumor Necrosis Factor - physiology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | CD28 Antigens - genetics | Membrane Proteins - physiology | CD28 Antigens - physiology | Receptors, Nerve Growth Factor - biosynthesis | Receptors, Antigen, T-Cell - metabolism | Membrane Proteins - genetics | Signal Transduction - genetics | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Receptors, Antigen, T-Cell - physiology | Intracellular Fluid - enzymology | Membrane Proteins - biosynthesis | Tyrosine - metabolism | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Mice | Receptors, Antigen, T-Cell - genetics | Antigens, Differentiation, T-Lymphocyte - biosynthesis | Antigens, CD | Inducible T-Cell Co-Stimulator Protein | T-Lymphocyte Subsets - immunology | Phosphorylation | Recombinant Fusion Proteins - physiology | Receptors, Nerve Growth Factor - physiology | Phosphatidylinositol 3-Kinases - metabolism | Receptors, OX40 | Tumor Necrosis Factor Receptor Superfamily, Member 9 | Receptors, Antigen, T-Cell - biosynthesis | Signal Transduction - immunology | Transfection | Antigens, Differentiation, T-Lymphocyte - physiology | Membrane Proteins - metabolism | Cytotoxicity Tests, Immunologic - methods | Intracellular Fluid - metabolism | Receptors, Tumor Necrosis Factor - genetics | Recombinant Fusion Proteins - biosynthesis | Cells, Cultured | Receptors, Nerve Growth Factor - genetics | Animals | T-Lymphocyte Subsets - enzymology | T-Lymphocyte Subsets - metabolism | Antigens, Differentiation, T-Lymphocyte - genetics | CD28 Antigens - biosynthesis | Receptors, Tumor Necrosis Factor - biosynthesis | Cytokines - biosynthesis | CD28 antigen | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2004, Volume 172, Issue 5, pp. 2778 - 2784
Journal Article
The Journal of Immunology, ISSN 0022-1767, 08/2005, Volume 175, Issue 4, pp. 2340 - 2348
ICOS is a new member of the CD28 family of costimulatory molecules that is expressed on activated T cells. Its ligand B7RP-1 is constitutively expressed on B... 
GERMINAL CENTER FORMATION | CXC CHEMOKINE RECEPTOR-5 | OX40 LIGAND | IMMUNE-RESPONSES | ACTIVATION MOLECULE | INDUCIBLE COSTIMULATOR | IMMUNOLOGY | LYMPHOID FOLLICLES | EXPRESSION | MICE LACKING | CUTTING EDGE | Spleen - immunology | Mice, Inbred A | Tumor Necrosis Factor-alpha - genetics | B-Lymphocyte Subsets - cytology | CD28 Antigens - genetics | Mice, Inbred CBA | CD40 Antigens - genetics | CD28 Antigens - physiology | CD40 Antigens - physiology | T-Lymphocytes, Helper-Inducer - metabolism | Membrane Proteins - genetics | Receptors, Cytokine - biosynthesis | Antibodies, Monoclonal - pharmacology | Antigens, Surface - biosynthesis | Spleen - cytology | Mice, Knockout | Cell Differentiation - immunology | Membrane Proteins - biosynthesis | Mice | Mice, Inbred BALB C | Antigens, Differentiation, T-Lymphocyte - biosynthesis | Tumor Necrosis Factor-alpha - biosynthesis | Receptors, CXCR5 | Inducible T-Cell Co-Stimulator Protein | Germinal Center - immunology | Tumor Necrosis Factors | Receptors, OX40 | Tumor Necrosis Factor-alpha - deficiency | Cell Differentiation - genetics | Membrane Proteins - deficiency | Immunization, Secondary | T-Lymphocytes, Helper-Inducer - immunology | Antigens, Differentiation, T-Lymphocyte - physiology | Receptors, Chemokine - biosynthesis | T-Lymphocytes, Helper-Inducer - cytology | B-Lymphocyte Subsets - immunology | Female | Mice, Inbred DBA | Receptors, Tumor Necrosis Factor - deficiency | Membrane Glycoproteins - immunology | Germinal Center - cytology | Receptors, Tumor Necrosis Factor - genetics | B7-1 Antigen - immunology | Mice, Inbred C57BL | Antigens, Surface - genetics | Mice, SCID | Mice, Inbred C3H | Animals | Inducible T-Cell Co-Stimulator Ligand | Spleen - metabolism | Antibodies, Monoclonal - administration & dosage | Antigens, Differentiation, T-Lymphocyte - genetics | Chemokines, CXC - metabolism | Receptors, Tumor Necrosis Factor - biosynthesis | Index Medicus | Abridged Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 12/2010, Volume 122, Issue 24, pp. 2529 - 2537
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2005, Volume 174, Issue 11, pp. 6648 - 6656
Negative costimulatory signals mediated via cell surface molecules such as CTLA-4 and programmed death 1 (PD-1) play a critical role in down-modulating immune... 
CO-RECEPTORS | REJECTION | ALLOGRAFT SURVIVAL | B7 FAMILY | IMMUNOLOGY | CD28 RECEPTOR | BLOCKADE | DEATH-1 PD-1 PATHWAY | CARDIAC ALLOGRAFTS | EXPRESSION | LONG-TERM ACCEPTANCE | B7-1 Antigen - genetics | Peptides - antagonists & inhibitors | Antigens, CD - genetics | Antibodies, Blocking - administration & dosage | CD4-Positive T-Lymphocytes - immunology | B7-2 Antigen | Signal Transduction - immunology | Membrane Glycoproteins - physiology | Membrane Glycoproteins - antagonists & inhibitors | CD28 Antigens - genetics | Mice, Mutant Strains | CD8-Positive T-Lymphocytes - metabolism | Membrane Glycoproteins - immunology | CD4 Antigens - genetics | Heart Transplantation - immunology | B7-1 Antigen - immunology | B7-H1 Antigen | Mice, Inbred C57BL | Peptides - immunology | Programmed Cell Death 1 Ligand 2 Protein | CD4-Positive T-Lymphocytes - metabolism | B7-1 Antigen - physiology | Signal Transduction - genetics | Down-Regulation - genetics | Antigens, Differentiation - physiology | Membrane Glycoproteins - genetics | Mice, Knockout | CTLA-4 Antigen | Animals | Down-Regulation - immunology | CD8 Antigens - genetics | Antigens, CD - physiology | Programmed Cell Death 1 Receptor | Mice | Mice, Inbred BALB C | Graft Rejection - immunology | CD8-Positive T-Lymphocytes - immunology | Graft Rejection - genetics | Membrane Glycoproteins - deficiency | Antigens, Differentiation - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 11/2017, Volume 47, Issue 5, pp. 875 - 889.e10
Journal Article