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PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e83139 - e83139
CD28, CTLA-4 and PD-L1, the three identified ligands for CD80/86, are pivotal positive and negative costimulatory molecules that, among other functions,... 
IN-VITRO | ACTIVATION | DENDRITIC CELLS | TCR STOP-SIGNAL | TOLERANCE | MULTIDISCIPLINARY SCIENCES | EXTRINSIC CONTROL | ANTI-CD28 ANTIBODY | UP-REGULATION | CUTTING EDGE | LYMPHOCYTES | B7-1 Antigen - antagonists & inhibitors | Cell Communication - immunology | B7-2 Antigen - genetics | B7-1 Antigen - genetics | Dendritic Cells - immunology | Humans | Molecular Targeted Therapy | T-Lymphocytes, Regulatory - immunology | T-Lymphocytes, Cytotoxic - drug effects | CD28 Antigens - genetics | Protein Binding - drug effects | CD28 Antigens - antagonists & inhibitors | T-Lymphocytes, Regulatory - cytology | Dendritic Cells - drug effects | B7-2 Antigen - immunology | T-Lymphocytes, Cytotoxic - immunology | Gene Expression | B7-2 Antigen - antagonists & inhibitors | B7-1 Antigen - immunology | Antibodies, Monoclonal - pharmacology | CTLA-4 Antigen - genetics | CD28 Antigens - immunology | CTLA-4 Antigen - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Cell Movement - drug effects | T-Lymphocytes, Regulatory - drug effects | B7-H1 Antigen - antagonists & inhibitors | Lymphocyte Activation - drug effects | Cell Communication - drug effects | Dendritic Cells - cytology | CTLA-4 Antigen - antagonists & inhibitors | T-Lymphocytes, Cytotoxic - cytology | Viral antibodies | Antibodies | Antigens | B cells | T cells | Motility | Transplants & implants | Calcium | Blocking antibodies | Homeostasis | Effector cells | Reversing | Immunological synapses | Lymphocytes T | Kinases | CD28 antigen | T-cell receptor | CTLA-4 protein | Cell activation | Immunology | Lymphocytes | Dwell time | Cell cycle | Cytokines | Immunoregulation | CD80 antigen | T cell receptors | Costimulator | Microscopy | Antigen-presenting cells | PD-L1 protein | Ligands | Cell migration | Synapses | Apoptosis | Index Medicus | Life Sciences | Human health and pathology
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2015, Volume 194, Issue 3, pp. 911 - 920
Journal Article
Journal Article
Science, ISSN 0036-8075, 4/2011, Volume 332, Issue 6029, pp. 600 - 603
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2017, Volume 127, Issue 9, pp. 3462 - 3471
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e64138 - e64138
Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) is being evaluated in multiple clinical trials. Our current approach to... 
THERAPY | SPECIFICITY | PERSISTENCE | MULTIDISCIPLINARY SCIENCES | MALIGNANCIES | ADOPTIVE IMMUNOTHERAPY | TRANSPOSITION | Cell Proliferation | Antigen-Presenting Cells - cytology | Coculture Techniques | Humans | Mutant Chimeric Proteins - genetics | DNA Transposable Elements - immunology | Antigens, CD19 - genetics | Leukemia, B-Cell - therapy | T-Lymphocytes - transplantation | CD3 Complex - genetics | Interleukin-2 - immunology | CD28 Antigens - genetics | T-Lymphocytes - metabolism | Transposases - genetics | DNA Transposable Elements - genetics | Antigens, CD19 - immunology | Gene Transfer Techniques | Antigen-Presenting Cells - metabolism | Gene Expression | Immunotherapy, Adoptive - methods | Lymphocyte Activation | Hematopoietic Stem Cell Transplantation | Leukemia, B-Cell - pathology | Electroporation | Transposases - immunology | CD28 Antigens - immunology | Clinical Trials as Topic | Antigen-Presenting Cells - immunology | Interleukin-2 - genetics | T-Lymphocytes - cytology | CD3 Complex - immunology | K562 Cells | Mutant Chimeric Proteins - immunology | T-Lymphocytes - immunology | Leukemia, B-Cell - immunology | Genetic Therapy - methods | Antigens | Immunotherapy | Genetically modified organisms | Transplantation | T cells | Gene therapy | Hematopoietic stem cells | Cell culture | Pediatrics | Propagation | Interleukin | Adoptive immunotherapy | Clinical trials | Stem cell transplantation | Lymphocytes T | CD28 antigen | Adoptive transfer | Infusion | Transposition | Lymphocytes | Manufacturing | Genetic modification | Deoxyribonucleic acid--DNA | Autografts | Medical research | Cytomegalovirus | CD19 antigen | Risk groups | Cloning | Zebrafish | CD3 antigen | T cell receptors | Gene expression | Transposase | Hemopoiesis | Children & youth | Plasmids | Biopsy | Antigen-presenting cells | Quality control | Stem cells | Umbilical cord | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2000, Volume 192, Issue 7, pp. 1027 - 1034
Journal Article
Nature, ISSN 0028-0836, 03/2001, Volume 410, Issue 6828, pp. 608 - 611
Optimal immune responses require both an antigen-specific and a co-stimulatory signal. The shared ligands B7-1 and B7-2 on antigen-presenting cells deliver the... 
SYSTEM | ADHESION | RECOGNITION | SOLUBLE FORM | MULTIDISCIPLINARY SCIENCES | T-CELL ACTIVATION | RECEPTOR | CTLA-4 | COSTIMULATION | BLOCKADE | MOLECULAR-BASIS | B7-1 Antigen - genetics | Cricetulus | Humans | Crystallography, X-Ray | Abatacept | B7-1 Antigen - chemistry | CHO Cells | Cricetinae | B7-1 Antigen - immunology | Models, Molecular | Recombinant Proteins - chemistry | Macromolecular Substances | CTLA-4 Antigen | Immunity - physiology | Animals | Antigens, Differentiation - chemistry | Immunoconjugates | T-Lymphocytes - chemistry | Protein Conformation | T-Lymphocytes - immunology | Antigens, Differentiation - genetics | Mice | Mutation | Antigens, CD | Antigens, Differentiation - immunology | Cell culture | Residues | Animal models | Crystal lattices | CD86 antigen | Hydrogen | Central nervous system | Conservation | X-ray diffraction | Amino acids | Lymphocytes T | CD28 antigen | Crystallography | Cell surface | B7 antigen | Light sources | Proteins | T-cell receptor | Cell recognition | Cell activation | Immunology | Lymphocytes | Immunotherapy | Cell adhesion | Genetics | Dimerization | Elbow | Crystal structure | Antigens | Immunoglobulins | Oligomerization | Complementarity | Immune response | CD152 antigen | Macromolecules | Crystals | T cell receptors | Topology | Nitrogen | Computer programs | Interfaces | Diffraction | Antigen-presenting cells | Data collection | Ligands | B7-1 antigen | CD162 antigen | Binding sites | B7-2 antigen | CTLA-4 protein | Index Medicus
Journal Article