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Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, pp. 20254 - 20254
Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed in vitro to... 
MESSENGER-RNAS | CANCER-PATIENTS | EXTRACELLULAR VESICLES | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | MICROVESICLES | DIAGNOSTIC BIOMARKERS | INDUCE APOPTOSIS | OVARIAN-CANCER | MODULATION | LYMPHOCYTES | Exosomes - metabolism | Neoplasms - metabolism | CD8-Positive T-Lymphocytes - cytology | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Humans | Culture Media, Conditioned - pharmacology | RNA, Messenger - metabolism | Antigens, CD - metabolism | Lectins, C-Type - metabolism | T-Lymphocyte Subsets - drug effects | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Real-Time Polymerase Chain Reaction | Microscopy, Electron, Transmission | CD4-Positive T-Lymphocytes - cytology | Apyrase - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | Down-Regulation - drug effects | Up-Regulation - drug effects | T-Lymphocytes, Regulatory - drug effects | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | Adenosine - metabolism | Neoplasms - pathology | CD4-Positive T-Lymphocytes - drug effects | Microscopy, Fluorescence | Adenosine | Dendritic cells | CD8 antigen | Gene regulation | Data processing | T cell receptors | Lymphocytes T | Gene expression | Exosomes | Cell surface | CD4 antigen | Polymerase chain reaction | CD69 antigen | Cell activation | Lymphocytes | Down-regulation | Peripheral blood | Index Medicus
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2016, Volume 46, Issue 7, pp. 1770 - 1782
We previously demonstrated an accumulation of tumor‐reactive CD4 + CD8 + double positive (DP) T cells within melanoma‐infiltrating lymphocytes, supporting... 
CD4 | double‐positive T lymphocyte | CD8 | TIL | Melanoma | IL‐9R | IL‐9 | IL-9R | double-positive T lymphocyte | IL-9 | TH9 CELLS | CD8(+) | INDUCED APOPTOSIS | INTERLEUKIN-9 | RECEPTOR | PERIPHERAL-BLOOD | IMMUNOLOGY | CYTOKINE EXPRESSION | IN-VIVO | CD4(+) CD8(+) double-positive T lymphocyte | GROWTH-FACTOR | LYMPHOCYTES | T-Lymphocyte Subsets - immunology | Apoptosis - drug effects | Humans | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Interleukin-9 - pharmacology | Melanoma - genetics | T-Lymphocyte Subsets - drug effects | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Cytotoxicity, Immunologic - drug effects | Melanoma - metabolism | Receptors, Interleukin-9 - metabolism | Gene Expression | Cytokines - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Lymphocytes, Tumor-Infiltrating - drug effects | Melanoma - pathology | Cell Survival - immunology | Apoptosis - immunology | Receptors, Interleukin-9 - genetics | Lymphocyte Activation - drug effects | Melanoma - immunology | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | CD8-Positive T-Lymphocytes - immunology | Interleukin-9 - immunology | CD4-Positive T-Lymphocytes - drug effects | Lymphocytes, Tumor-Infiltrating - immunology | Parrots | T cells | Tumors | Index Medicus | Life Sciences | Cancer
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2019, Volume 49, Issue 6, pp. 966 - 968
It is a matter of current debate whether the bone marrow is a hub for circulating memory T lymphocytes and/or the home of resident memory T lymphocytes. Here... 
Spleen | Bone marrow | Tissue‐resident signature genes | Memory T cells | CD69 | Tissue-resident signature genes | Animal experimentation | Antigens | T cells | Gene expression | Analysis | Genes | Cell proliferation | CD69 antigen | Memory cells | Immunological memory | Lymphocytes | CD8 antigen | Lymphocytes T | CD4 antigen | Letter to the Editor
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2017, Volume 199, Issue 7, pp. 2225 - 2235
Journal Article
Journal Article
Pancreas, ISSN 0885-3177, 01/2004, Volume 28, Issue 1, pp. e26 - 31
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 04/2012, Volume 109, Issue 16, pp. 6187 - 6192
IL-15 has potential as an immunotherapeutic agent for cancer treatment because of its ability to effectively stimulate CD8 T cell, natural killer T cell, and... 
LUNG-CANCER | RESPONSES | IMMUNITY | GROWTH-FACTOR-BETA | TOLERANCE | MULTIDISCIPLINARY SCIENCES | CTLA-4 | PROLIFERATION | PD-1 | IL-10 | CUTTING EDGE | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Humans | Male | Interferon-gamma - metabolism | Prostatic Neoplasms - immunology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Flow Cytometry | T-Lymphocyte Subsets - drug effects | Antibodies - immunology | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Cytotoxicity, Immunologic - drug effects | Prostatic Neoplasms - drug therapy | Disease Models, Animal | Amino Acid Sequence | Prostatic Neoplasms - pathology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Kaplan-Meier Estimate | CTLA-4 Antigen - metabolism | Treatment Outcome | Interleukin-5 - administration & dosage | Lymphocytes, Tumor-Infiltrating - drug effects | CTLA-4 Antigen - immunology | B7-H1 Antigen - immunology | Antibodies - administration & dosage | B7-H1 Antigen - metabolism | T-Lymphocytes, Regulatory - drug effects | Animals | Tumor Burden - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Cell Line, Tumor | Mice | CD8-Positive T-Lymphocytes - immunology | Cytotoxicity, Immunologic - immunology | CD4-Positive T-Lymphocytes - drug effects | Lymphocytes, Tumor-Infiltrating - immunology | Tumor Burden - immunology | Interleukins | Immunotherapy | Physiological aspects | Development and progression | T cells | Health aspects | Prostate cancer | Clinical trials | T cell receptors | Cytokines | Rodents | Tumors | Index Medicus | Adenocarcinoma | Animal models | Cell survival | CD8 antigen | Immunoregulation | Antibodies | Cytotoxicity | Lymphocytes T | Interleukin 15 | CD4 antigen | CTLA-4 protein | PD-L1 protein | gamma -Interferon | Antitumor activity | CD25 antigen | Natural killer cells | Prostate | Biological Sciences
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 02/2017, Volume 76, Issue 2, pp. 377 - 385
ObjectivesIgG4-related disease (IgG4-RD) is a chronic, systemic, inflammatory condition of unknown aetiology. We have recently described clonally expanded... 
Sjøgren's Syndrome | Inflammation | T Cells | CELLS | LABIAL SALIVARY-GLANDS | HELPER SUBSETS | BIOINFORMATICS | REGULATORY IMMUNE-REACTIONS | SJOGRENS-SYNDROME | PANCREATITIS | RHEUMATOLOGY | ATOPY | MIKULICZS-DISEASE | TH2 | Dacryocystitis - genetics | Perforin - genetics | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Chemokine CCL4 - genetics | Sjogren's Syndrome - immunology | Male | Dacryocystitis - immunology | Gene Expression Profiling | Granzymes - genetics | Sjogren's Syndrome - metabolism | RNA, Messenger - metabolism | Sialadenitis - genetics | Case-Control Studies | Autoimmune Diseases - genetics | CD4-Positive T-Lymphocytes - immunology | Young Adult | Immunoglobulin G - immunology | Aged, 80 and over | Adult | Female | Sialadenitis - metabolism | Interferon-gamma - genetics | Autoimmune Diseases - metabolism | Signaling Lymphocytic Activation Molecule Family - genetics | Sjogren's Syndrome - genetics | T-Lymphocytes, Cytotoxic - immunology | CD4 Antigens - immunology | Autoimmune Diseases - immunology | Submandibular Gland - metabolism | Transforming Growth Factor beta1 - genetics | T-Box Domain Proteins - genetics | Dacryocystitis - metabolism | Interferon-gamma - immunology | Chemokine CCL5 - genetics | Fluorescent Antibody Technique | Aged | Sialadenitis - immunology | Index Medicus
Journal Article