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Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 531, Issue 7593, pp. 253 - 257
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 6, p. e0128714
Introduction Understanding the factors that delineate the efficacy of T cell responses towards pathogens is crucial for our ability to develop potent therapies... 
ANTIGEN-SENSITIVITY | VIRUS | MULTIDISCIPLINARY SCIENCES | DISEASE | T-Lymphocyte Subsets - immunology | Leishmania major - immunology | CD8-Positive T-Lymphocytes - pathology | Humans | CD8-Positive T-Lymphocytes - parasitology | CD4-Positive T-Lymphocytes - parasitology | CD4-Positive T-Lymphocytes - pathology | Leishmaniasis, Cutaneous - immunology | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV Infections - pathology | Clone Cells | CD4-Positive T-Lymphocytes - virology | Cytokines - immunology | Datasets as Topic | HIV Infections - virology | Leishmaniasis, Cutaneous - pathology | Immunophenotyping | Immunity, Innate | T-Lymphocyte Subsets - virology | HIV-1 - immunology | Models, Immunological | Algorithms | T-Lymphocyte Subsets - pathology | Leishmaniasis, Cutaneous - parasitology | T-Lymphocyte Subsets - parasitology | CD8-Positive T-Lymphocytes - virology | CD8-Positive T-Lymphocytes - immunology | Cytokines - biosynthesis | Cytotoxicity, Immunologic | Infection | T cells | Health aspects | Analysis | Evaluation | Pathogens | Antigens | Parameter estimation | Effectiveness | Cytokines | Control methods | CD8 antigen | Effector cells | Infections | Lymphocytes T | Molecular chains | CD4 antigen | Datasets | Infectious diseases | Lymphocytes | Correlation analysis | Human immunodeficiency virus--HIV | In vivo methods and tests | Combinatorial analysis | Quantitative analysis | Life Sciences | Human health and pathology | HIV | Human immunodeficiency virus
Journal Article
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 135, Issue 3, pp. 626 - 635
The immune system has tailored its effector functions to optimally respond to distinct species of microbes. Based on emerging knowledge on the different... 
Allergy and Immunology | TC2 | TC1 | TC17/TC22 | Type 1 immunity | type 3 immunity | innate lymphoid cells | TH17/TH22 | TH1 | type 2 immunity | TH2 | 17/T | TISSUE-INDUCER CELLS | ROR-GAMMA-T | T(C)1 | IFN-GAMMA | T(H)17/T(H)22 | T(C)2 | IMMUNOLOGY | T(H)1 | CD8(+) T-CELLS | T(H)2 | T(C)17/T(C)22 | CHRONIC RHINOSINUSITIS | ATOPIC-DERMATITIS | HELPER 17 CELLS | ALLERGY | ALLERGIC DISEASE | LYMPHOID-CELLS | CHEMOKINE RECEPTORS | Communicable Diseases - pathology | Humans | Autoimmunity - genetics | Hypersensitivity - immunology | Communicable Diseases - genetics | Th2 Cells - immunology | CD4-Positive T-Lymphocytes - pathology | Eosinophils - immunology | T-Lymphocytes, Cytotoxic - pathology | CD4-Positive T-Lymphocytes - immunology | Basophils - pathology | Basophils - immunology | Hypersensitivity - genetics | Eosinophils - pathology | Th2 Cells - pathology | Cytokines - immunology | Th17 Cells - pathology | Adaptive Immunity | Biomarkers - metabolism | T-Lymphocytes, Cytotoxic - immunology | Mast Cells - immunology | Gene Expression | Immunity, Innate | Hypersensitivity - pathology | Mast Cells - pathology | Communicable Diseases - immunology | Th17 Cells - immunology | Communicable Diseases - microbiology | Immunity, Cellular | Immunoglobulin E | T cells | Tretinoin | Transcription factors | Cytokines | Lymphocytes | Cytotoxicity | Ligands | Chemokines | Immune system
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 4, p. e0154564
It has been established that mammalian target of Rapamycin (mTOR) inhibitors have anti-inflammatory effects in models of experimental colitis. However, the... 
B-CELLS | INTESTINAL INFLAMMATION | INFLAMMATORY-BOWEL-DISEASE | CROHNS-DISEASE | DENDRITIC CELLS | GM-CSF | MULTIDISCIPLINARY SCIENCES | IN-VIVO | KINASE INHIBITOR | ANTITUMOR-ACTIVITY | TH17 CELLS | T-Lymphocyte Subsets - immunology | Th1 Cells - pathology | CD8-Positive T-Lymphocytes - pathology | Colon - drug effects | Colitis - pathology | Colon - immunology | Male | CD4-Positive T-Lymphocytes - pathology | Th1 Cells - immunology | T-Lymphocytes, Regulatory - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | TOR Serine-Threonine Kinases - antagonists & inhibitors | Th17 Cells - drug effects | T-Lymphocyte Subsets - drug effects | Inflammation Mediators - metabolism | Disease Models, Animal | Th17 Cells - pathology | Th1 Cells - drug effects | Colon - pathology | Mice, Inbred C57BL | Morpholines - pharmacology | Dextran Sulfate - toxicity | Colitis - etiology | T-Lymphocytes, Regulatory - drug effects | Animals | T-Lymphocyte Subsets - pathology | Cell Differentiation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Th17 Cells - immunology | Cell Proliferation - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | Colitis - prevention & control | CD4-Positive T-Lymphocytes - drug effects | Dextran | Prevention | Dosage and administration | Interferon | Inflammation | Research | Colitis | T cells | CD8 antigen | Body weight | Body weight loss | Proteins | Cell growth | Surgery | Peripheral blood | Dextran sulfate | Bone marrow | Spleen | Cytokines | Lamina propria | Rapamycin | Gene expression | Studies | Inflammatory bowel disease | Hospitals | Sodium | Interleukin 10 | Cell proliferation | Animal models | Phosphorylation | Inflammatory bowel diseases | Leukemia | Interleukin | Helper cells | Lymphocytes T | Kinases | Sulfates | Autophagy | Lymph nodes | Interleukin 6 | Ethics | Granulocytes | Lymphocytes | Intestine | Rodents | Gastroenterology | Colon | Dendritic cells | Histology | CD4 antigen | Medicine | Sulfate | Laboratory animals
Journal Article
Arthritis research & therapy, ISSN 1478-6354, 2013, Volume 15, Issue 5, pp. R136 - R136
Introduction: The aim of this study was to characterize interleukin 17 (IL-17) and interleukin 22 (IL-22) producing cells in peripheral blood (PB), skin,... 
RHEUMATOID-ARTHRITIS | MATRIX METALLOPROTEINASES | SYNOVIAL-FLUID | INTERLEUKIN 22 | AUTOIMMUNE ARTHRITIS | PERIPHERAL-BLOOD | PROINFLAMMATORY CYTOKINES | RHEUMATOLOGY | POTENTIAL ROLE | T-CELLS | SKIN INFLAMMATION | Immunohistochemistry | Receptors, CCR6 - immunology | Leukocytes, Mononuclear - metabolism | Receptors, CCR4 - immunology | Skin - metabolism | Humans | Interleukins - cerebrospinal fluid | Middle Aged | Interleukin-17 - immunology | Synovial Membrane - immunology | Synovial Membrane - pathology | Male | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Receptors, Interleukin - metabolism | Receptors, CCR4 - metabolism | Arthritis, Psoriatic - pathology | Flow Cytometry | Psoriasis - pathology | Th17 Cells - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Interleukins - immunology | Leukocytes, Mononuclear - immunology | Psoriasis - metabolism | Receptors, CCR6 - metabolism | Adult | Female | T-Lymphocytes, Helper-Inducer - pathology | Arthritis, Psoriatic - metabolism | Skin - pathology | Skin - immunology | Th17 Cells - pathology | Interleukin-17 - blood | Psoriasis - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Interleukins - blood | Receptors, Interleukin - immunology | CD4-Positive T-Lymphocytes - metabolism | Interleukin-17 - cerebrospinal fluid | Synovial Membrane - metabolism | Leukocytes, Mononuclear - pathology | Arthritis, Psoriatic - immunology | Lymphocyte Count | Th17 Cells - immunology | Aged | Interleukins | T cells | Osteoarthritis | Enzyme-linked immunosorbent assay | Psoriatic arthritis
Journal Article
Nature (London), ISSN 1476-4687, 2015, Volume 523, Issue 7562, pp. 612 - 616
The clinical course of autoimmune and infectious disease varies greatly, even between individuals with the same condition. An understanding of the molecular... 
RESPONSES | INTERFERON | PREDICTS PROGNOSIS | ACUTE HEPATITIS-C | MULTIDISCIPLINARY SCIENCES | DISEASE | BIOLOGY | GENE-EXPRESSION | ACTIVITY INDEX | SIGNATURE | Inflammation - pathology | CD8-Positive T-Lymphocytes - pathology | Humans | Inflammatory Bowel Diseases - immunology | Transcriptome | Autoimmunity - genetics | Infection - virology | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - pathology | Autoimmune Diseases - genetics | CD4-Positive T-Lymphocytes - immunology | Autoimmunity - immunology | Inflammatory Bowel Diseases - pathology | Inflammatory Bowel Diseases - genetics | Lupus Erythematosus, Systemic - immunology | CD8-Positive T-Lymphocytes - metabolism | Receptors, Antigen, T-Cell - immunology | Autoimmune Diseases - pathology | Receptors, Interleukin-7 - immunology | Receptors, Interleukin-7 - metabolism | Infection - immunology | Autoimmune Diseases - immunology | CD4-Positive T-Lymphocytes - metabolism | Inflammation - virology | Programmed Cell Death 1 Receptor - metabolism | Inflammation - immunology | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - genetics | Infection - genetics | Phenotype | Animals | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology | Infection - pathology | Lupus Erythematosus, Systemic - genetics | Mice | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | Lupus Erythematosus, Systemic - pathology | CD2 Antigens - immunology | Viral antibodies | Antibodies | Interferon | T cells | Health aspects | Analysis | Hepatitis | Disease | Lymphocytes | T cell receptors | Infections | Genetic engineering | Regression analysis | Gene expression | Viral infections
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2007, Volume 104, Issue 16, pp. 6776 - 6781
Journal Article