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1. Full Text Soluble CD40 Ligand in Acute Coronary Syndromes
by Heeschen, Christopher and Dimmeler, Stefanie and Hamm, Christian W and van den Brand, Marcel J and Boersma, Eric and Zeiher, Andreas M and Simoons, Maarten L
The New England Journal of Medicine, ISSN 0028-4793, 03/2003, Volume 348, Issue 12, pp. 1104 - 1111
CD40 ligand is released from activated platelets and promotes inflammation and coagulation. In this study of patients with acute coronary syndromes, increased... 
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2. Full Text Soluble CD40 ligand in acute coronary syndromes
by Heeschen, C and Dimmeler, S and Hamm, C.W and CAPTURE Study Investigators
ACC Current Journal Review, ISSN 1062-1458, 2003, Volume 12, Issue 3, pp. 12 - 13
textabstractBACKGROUND: CD40 ligand is expressed on platelets and released from them on activation. We investigated the predictive value of soluble CD40 ligand... 
MEDICINE, GENERAL & INTERNAL | ACTIVATION | TROPONIN-I PREDICTS | REFRACTORY UNSTABLE ANGINA | T LEVELS | ENDOTHELIAL-CELLS | ACUTE MYOCARDIAL-INFARCTION | P-SELECTIN | RISK | PROGNOSTIC VALUE | TISSUE FACTOR | Myocardial Infarction - blood | Acute Disease | Prognosis | Follow-Up Studies | CD40 Ligand - blood | Humans | Middle Aged | Risk Factors | Angina Pectoris - drug therapy | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Biomarkers - blood | Immunoglobulin Fab Fragments - therapeutic use | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Randomized Controlled Trials as Topic | Angina Pectoris - blood | Myocardial Infarction - drug therapy | Platelet Activation | Survival Analysis | Female | Platelet Aggregation Inhibitors - therapeutic use | Physiological aspects | Coronary heart disease | Health aspects | Ligands (Biochemistry) | Heart attack | Risk factors | Cardiovascular disease | Heart attacks | Angina pectoris | Coronary vessels
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3. Full Text Soluble CD40 ligand contributes to blood–brain barrier breakdown and central nervous system inflammation in multiple sclerosis and neuromyelitis optica spectrum disorder
by Masuda, Hiroki and Mori, Masahiro and Uchida, Tomohiko and Uzawa, Akiyuki and Ohtani, Ryohei and Kuwabara, Satoshi
Journal of Neuroimmunology, ISSN 0165-5728, 2016, Volume 305, pp. 102 - 107
Abstract Soluble CD40 ligand (sCD40L) is reported to disrupt the blood–brain barrier (BBB). Cerebrospinal fluid (CSF) and serum sCD40L levels were measured in... 
Neurology | Allergy and Immunology | Multiple sclerosis | Neuromyelitis optica | Cerebrospinal fluid | Blood-brain barrier | CD40 ligand | Central nervous system | ANTIBODIES | PROTEIN | LUPUS-ERYTHEMATOSUS | IMMUNOLOGY | CEREBROSPINAL-FLUID | NEUROSCIENCES | INTERLEUKIN-17 PRODUCTION | RESPONSES | ELEVATED LEVELS | DISEASE | DIAGNOSTIC-CRITERIA | T-CELLS | Disability Evaluation | Multiple Sclerosis - blood | Multiple Sclerosis - cerebrospinal fluid | CD40 Ligand - blood | Humans | Middle Aged | Blood-Brain Barrier - physiopathology | Central Nervous System - pathology | Male | Neuromyelitis Optica - pathology | Inflammation | Statistics as Topic | Neuromyelitis Optica - blood | Young Adult | CD40 Ligand - cerebrospinal fluid | Neuromyelitis Optica - cerebrospinal fluid | Interleukin-6 - blood | Statistics, Nonparametric | Multiple Sclerosis - pathology | Adult | Female | Aged | Interleukin-6 - cerebrospinal fluid | Medical colleges | Systemic lupus erythematosus | Interleukins | Albumin
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4. Full Text High-sensitivity C-reactive protein and soluble CD40 ligand as indices of inflammation and platelet activation in 880 patients with nonvalvular atrial fibrillation: Relationship to stroke risk factors, stroke risk stratification schema, and prognosis
by Lip, Gregory Y.H and Patel, Jeetesh V and Hughes, Elizabeth and Hart, Robert G
Stroke, ISSN 0039-2499, 04/2007, Volume 38, Issue 4, pp. 1229 - 1237
Background and Purpose-There is now considerable evidence that atrial fibrillation is associated with an inflammatory state. We tested the hypothesis that... 
Soluble CD40 ligand | Stroke | C-reactive protein | Atrial fibrillation | CD154 | CARDIOVASCULAR EVENTS | PREVENTION | stroke | VON-WILLEBRAND-FACTOR | ASPIRIN | CLINICAL NEUROLOGY | ANTICOAGULATION | atrial fibrillation | THERAPY | PLASMA-LEVELS | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | soluble CD40 ligand | ARTERY-DISEASE | Predictive Value of Tests | Prognosis | Clinical Trials as Topic - statistics & numerical data | CD40 Ligand - blood | Humans | Middle Aged | Platelet Activation - immunology | Male | CD40 Ligand - immunology | Inflammation - blood | CD40 Ligand - analysis | C-Reactive Protein - metabolism | Adult | Female | Stroke - epidemiology | Inflammation - diagnosis | C-Reactive Protein - analysis | Stroke - prevention & control | Comorbidity | Risk Factors | Inflammation Mediators - blood | Anticoagulants - therapeutic use | Inflammation - epidemiology | Stroke - blood | Atrial Fibrillation - epidemiology | Aged | C-Reactive Protein - immunology | Cohort Studies
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5. Full Text Enhanced Levels of Soluble CD40 Ligand Exacerbate Platelet Aggregation and Thrombus Formation Through a CD40-Dependent Tumor Necrosis Factor Receptor–Associated Factor-2/Rac1/p38 Mitogen-Activated Protein Kinase Signaling Pathway
by Yacoub, Daniel and Hachem, Ahmed and Théorêt, Jean-François and Gillis, Marc-Antoine and Mourad, Walid and Merhi, Yahye
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2010, Volume 30, Issue 12, pp. 2424 - 2433
OBJECTIVE—CD40 ligand is a thromboinflammatory molecule that predicts cardiovascular events. Platelets constitute the major source of soluble CD40 ligand... 
CD40L | thrombosis | signal transduction | platelets | MECHANISM | ACUTE CORONARY SYNDROMES | RELEASE | B-CELL PROLIFERATION | INHIBITION | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | EXPRESSION | T-CELLS | TISSUE FACTOR | Blood Platelets - immunology | Actins - blood | CD40 Ligand - blood | Humans | Male | Blood Platelets - enzymology | Leukocytes - immunology | Neuropeptides - blood | Time Factors | Cell Shape | TNF Receptor-Associated Factor 2 - blood | p38 Mitogen-Activated Protein Kinases - blood | Female | CD40 Antigens - genetics | Thrombosis - blood | Disease Models, Animal | Signal Transduction | Mice, Inbred C57BL | Thrombosis - enzymology | Thrombosis - immunology | Mice, Knockout | Platelet Aggregation | Recombinant Proteins - blood | Animals | rac GTP-Binding Proteins - blood | CD40 Ligand - genetics | CD40 Antigens - blood | rac1 GTP-Binding Protein - blood | Mice | Mutation
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6. Full Text Elevated serum soluble CD40 ligand in cancer patients may play an immunosuppressive role
by Huang, Jianping and Jochems, Caroline and Talaie, Tara and Anderson, Austin and Jales, Alessandra and Tsang, Kwong Y and Madan, Ravi A and Gulley, James L and Schlom, Jeffrey
Blood, ISSN 0006-4971, 10/2012, Volume 120, Issue 15, pp. 3030 - 3038
Tumor cells can induce certain cytokines and soluble receptors that have a suppressive effect on the immune system. In this study, we showed that an... 
SURVIVAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | IL-12 PRODUCTION | IMMUNE-SYSTEM | PLASMA-LEVELS | ENDOTHELIAL-CELLS | INVOLVEMENT | SUPPRESSOR-CELLS | PLATELET ACTIVATION | HEMATOLOGY | METASTATIC PROSTATE-CANCER | Cell Proliferation | Monocytes - cytology | CD40 Ligand - blood | Humans | Middle Aged | Interleukin-10 - blood | Male | Monocytes - metabolism | Case-Control Studies | CD4-Positive T-Lymphocytes - immunology | Young Adult | Flow Cytometry | Neoplasms - blood | Immune Tolerance - immunology | Interleukin-6 - blood | Leukocytes, Mononuclear - immunology | Adult | Female | Enzyme-Linked Immunosorbent Assay | Lymphocyte Activation | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Blotting, Western | Immunosuppression | Neoplasms - immunology | Neoplasms - pathology | Clinical Trials, Phase II as Topic | Immunobiology
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7. Full Text Soluble CD40 ligand, soluble P-selectin, interleukin-6, and tissue factor in diabetes mellitus - Relationships to cardiovascular disease and risk factor intervention
by Lim, HS and Blann, AD and Lip, GYH
CIRCULATION, ISSN 0009-7322, 06/2004, Volume 109, Issue 21, pp. 2524 - 2528
Background - High levels of the soluble fragment of CD40 ligand (sCD40L) have previously been associated with adverse cardiovascular outcomes. CD40L - CD40... 
CD154 | CARDIAC & CARDIOVASCULAR SYSTEMS | tissue factor | CD40 ligand | PLATELETS | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | diabetes mellitus | ACUTE CORONARY SYNDROMES | HEMATOLOGY | interleukin-6 | P-selectin | Diabetes Mellitus - blood | Follow-Up Studies | CD40 Ligand - blood | Humans | Middle Aged | Male | Hypercholesterolemia - drug therapy | Risk Management | Interleukin-6 - blood | Blood Coagulation | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Female | Aspirin - therapeutic use | Platelet Aggregation Inhibitors - therapeutic use | Hypoglycemic Agents - therapeutic use | Risk Factors | Diabetes Mellitus - drug therapy | Thromboplastin - analysis | Inflammation | Platelet Activation | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Biomarkers | P-Selectin - blood | Hypercholesterolemia - complications | Aged | Cohort Studies
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8. Full Text Soluble CD40 ligand, platelet surface CD40 ligand, and total platelet CD40 ligand in atrial fibrillation: Relationship to soluble p-selectin, stroke risk factors, and risk factor intervention
by Choudhury, Anirban and Chung, Irene and Panja, Nimai and Patel, Jeetesh and Lip, Gregory Y. H
Chest, ISSN 0012-3692, 2008, Volume 134, Issue 3, pp. 574 - 581
Background: Abnormal levels of soluble CD40 ligand (sCD40L) have been reported in patients with hypertension, coronary artery disease, diabetes mellitus, heart... 
Platelet lysate | Platelet activation | Soluble CD40 | Atrial fibrillation | CD40 ligand | C-REACTIVE PROTEIN | platelet lysate | ENDOTHELIAL DAMAGE | ACUTE CORONARY SYNDROMES | VON-WILLEBRAND-FACTOR | platelet activation | soluble CD40 | BETA-THROMBOGLOBULIN | atrial fibrillation | GLYCOPROTEIN IIB/IIIA | PLASMA-LEVELS | RESPIRATORY SYSTEM | ANTITHROMBOTIC THERAPY | TISSUE FACTOR | ARTERY-DISEASE | Atrial Fibrillation - drug therapy | CD40 Ligand - blood | Humans | Middle Aged | Risk Factors | Male | Case-Control Studies | Atrial Fibrillation - blood | Regression Analysis | Blood Platelets - metabolism | Fibrinolytic Agents - therapeutic use | P-Selectin - blood | Female | Stroke - epidemiology | Aged | Cell Membrane - metabolism
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9. Full Text Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18
by Morrow, David A and Sabatine, Marc S and Brennan, Marie-Luise and de Lemos, James A and Murphy, Sabina A and Ruff, Christian T and Rifai, Nader and Cannon, Christopher P and Hazen, Stanley L
European Heart Journal, ISSN 0195-668X, 5/2008, Volume 29, Issue 9, pp. 1096 - 1102
Aims We investigated the prognostic performance of myeloperoxidase (MPO), and soluble CD40 ligand (sCD40L) along with B-type natriuretic peptide (BNP),... 
Myocardial infarction | Biomarkers | Prognosis | Unstable angina | C-REACTIVE PROTEIN | REVASCULARIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | biomarkers | myocardial infarction | NATRIURETIC PEPTIDE | prognosis | PROGNOSTIC VALUE | PREDICT MORTALITY | CARDIOVASCULAR-DISEASE | TROPONIN-T | unstable angina | STRATIFICATION | ARTERY-DISEASE | Biomarkers - metabolism | Predictive Value of Tests | Recurrence | Risk Assessment | CD40 Ligand - blood | Humans | Middle Aged | Angina, Unstable - diagnosis | Male | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Troponin I - blood | C-Reactive Protein - metabolism | Acute Coronary Syndrome - diagnosis | Creatine Kinase, MB Form - blood | Female | Aged | Peroxidase - blood | Natriuretic Peptide, Brain - blood
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10. Full Text Biologically Active CD40 Ligand Is Elevated in Sickle Cell Anemia: Potential Role for Platelet-Mediated Inflammation
by Lee, Sheritha P and Ataga, Kenneth I and Orringer, Eugene P and Phillips, David R and Parise, Leslie V
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2006, Volume 26, Issue 7, pp. 1626 - 1631
OBJECTIVE—After activation, platelets expose CD40 ligand (CD40L) on their surface, then subsequently release the inflammatory mediator as a soluble fragment... 
CD40L | Inflammation | Sickle cell anemia | Platelets | Coagulation | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | ERYTHROCYTE ADHERENCE | coagulation | VASCULAR ENDOTHELIUM | platelets | TISSUE FACTOR EXPRESSION | HUMAN ENDOTHELIAL-CELLS | inflammation | DISEASE | P-SELECTIN | PERIPHERAL VASCULAR DISEASE | STEADY-STATE | HEMATOLOGY | sickle cell anemia | PROCOAGULANT ACTIVITY | Cell Proliferation | Anemia, Sickle Cell - complications | CD40 Ligand - blood | Humans | Middle Aged | Monocytes - metabolism | Inflammation - etiology | Case-Control Studies | Hemoglobin, Sickle - metabolism | Intercellular Adhesion Molecule-1 - metabolism | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Blood Platelets - metabolism | Adult | Anemia, Sickle Cell - blood | B-Lymphocytes - pathology | Thromboplastin - metabolism | Thromboplastin - biosynthesis
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11. Elevated levels of soluble CD40 ligand are associated with antiphospholipid antibodies in patients with systemic lupus erythematosus
by Kim, Ki-Jo and Baek, In-Won and Yoon, Chong-Hyeon and Kim, Wan-Uk and Cho, Chul-Soo
Clinical and Experimental Rheumatology, ISSN 0392-856X, 2017, Volume 35, Issue 5, pp. 823 - 830
Objective The CD40L/CD40 pathway is involved in the pathophysiology of atherothrombotic disease, and elevated levels of soluble CD40L (sCD40L) were reported in... 
Antiphospholipid | CD40 ligand | Systemic lupus erythematosus | OXIDATIVE STRESS | MYOCARDIAL-INFARCTION | ACUTE CORONARY SYNDROMES | ADHESION MOLECULES | RHEUMATOLOGY | antiphospholipid | TISSUE FACTOR EXPRESSION | DIABETIC-PATIENTS | systemic lupus erythematosus | IMMUNE-SYSTEM | PLASMA-LEVELS | ENDOTHELIAL-CELLS | PLATELET ACTIVATION | Arterial Occlusive Diseases - blood | Arterial Occlusive Diseases - immunology | Up-Regulation | Lupus Erythematosus, Systemic - complications | Antibodies, Antiphospholipid - blood | CD40 Ligand - blood | Humans | Thrombosis - immunology | Male | Lupus Erythematosus, Systemic - blood | Biomarkers - blood | Lupus Erythematosus, Systemic - diagnosis | Arterial Occlusive Diseases - etiology | Thrombosis - etiology | Blood Coagulation | Lupus Erythematosus, Systemic - immunology | P-Selectin - blood | Adult | Female | Retrospective Studies | Thrombosis - blood
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12. Full Text Proinflammatory Adaptive Cytokine and Shed Tumor Necrosis Factor Receptor Levels Are Elevated Preceding Systemic Lupus Erythematosus Disease Flare
by Munroe, Melissa E and Vista, Evan S and Guthridge, Joel M and Thompson, Linda F and Merrill, Joan T and James, Judith A
Arthritis & Rheumatology, ISSN 2326-5191, 07/2014, Volume 66, Issue 7, pp. 1888 - 1899
Objective Systemic lupus erythematosus (SLE) is a multifaceted disease characterized by immune dysregulation and unpredictable disease activity. This study... 
RHEUMATOID-ARTHRITIS | REVISED CRITERIA | REGULATORY T-CELLS | VACCINATION | CLASSIFICATION | SERUM | RHEUMATOLOGY | EXPRESSION | SLE | TH1/TH2 CYTOKINES | BALANCE | fas Receptor - blood | Receptors, Tumor Necrosis Factor, Type I - immunology | CD40 Ligand - blood | Humans | Middle Aged | Fas Ligand Protein - blood | Lupus Erythematosus, Systemic - metabolism | Receptors, Tumor Necrosis Factor, Type II - immunology | CD40 Ligand - immunology | Fas Ligand Protein - immunology | fas Receptor - immunology | Receptors, Tumor Necrosis Factor, Type II - blood | Lupus Erythematosus, Systemic - immunology | Adult | Female | Adaptive Immunity - immunology | Cytokines - blood | Cytokines - immunology | Inflammation Mediators - immunology | Severity of Illness Index | Receptors, Tumor Necrosis Factor, Type I - blood | Lupus Erythematosus, Systemic - epidemiology | Risk Factors | Inflammation Mediators - blood | Biomarkers - blood | Lupus | Gangrene | Tumor necrosis factor-TNF | Cytokines | Autoimmune diseases | Rodents
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13. Full Text Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: A novel target of thiazolidinediones
by Varo, Nerea and Vicent, David and Libby, Peter and Nuzzo, Rebecca and Calle-Pascual, Alfonso L and Bernal, María Rosa and Fernández-Cruz, Arturo and Veves, Aristidis and Jarolim, Petr and Varo, Jose Javier and Goldfine, Allison and Horton, Edward and Schönbeck, Uwe
Circulation, ISSN 0009-7322, 06/2003, Volume 107, Issue 21, pp. 2664 - 2669
Background - Considerable evidence implicates the proinflammatory cytokine CD40 ligand (CD40L) in atherosclerosis and accumulating data link type 1 and 2... 
Inflammation | Immunology | Diabetes mellitus | Atherosclerosis | atherosclerosis | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | ROSIGLITAZONE TREATMENT | GAMMA PPAR-GAMMA | diabetes mellitus | INTERLEUKIN-6 | inflammation | INSULIN-RESISTANCE | DISEASE | PERIPHERAL VASCULAR DISEASE | immunology | EXPRESSION | ASSOCIATION | Metformin - therapeutic use | CD40 Ligand - blood | Humans | Male | Reference Values | Thiazoles - therapeutic use | Adult | Female | Arteriosclerosis - blood | Arteriosclerosis - etiology | Body Mass Index | Hypoglycemic Agents - therapeutic use | Acute Disease | Cross-Sectional Studies | Risk Factors | Solubility | Transcription Factors - antagonists & inhibitors | Treatment Outcome | Spain | Diabetes Mellitus, Type 2 - blood | Pilot Projects | Chromans - therapeutic use | Diabetes Mellitus, Type 1 - blood | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Aged | Diabetes Mellitus, Type 2 - drug therapy | Chronic Disease | Longitudinal Studies | Thiazolidinediones
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14. Full Text Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes
by Gerdes, Norbert and Seijkens, Tom and Lievens, Dirk and Kuijpers, Marijke J. E and Winkels, Holger and Projahn, Delia and Hartwig, Helene and Beckers, Linda and Megens, Remco T. A and Boon, Louis and Noelle, Randolph J and Soehnlein, Oliver and Heemskerk, Johan W. M and Weber, Christian and Lutgens, Esther
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2016, Volume 36, Issue 3, pp. 482 - 490
Beyond their eminent role in hemostasis and thrombosis, platelets are recognized as mediators of inflammation. Platelet cluster of differentiation 40 (CD40)... 
atherosclerosis | blood platelets | RISK | ACUTE CORONARY SYNDROMES | MONOCLONAL-ANTIBODY | SOLUBLE CD40L | CD40 ligand | IN-VIVO | DISEASE | immune system | ACUTE MYOCARDIAL-INFARCTION | leukocytes | PERIPHERAL VASCULAR DISEASE | MICE | LIGAND CD154 | HEMATOLOGY | UP-REGULATION | Inflammation - pathology | Platelet Adhesiveness | Apolipoproteins E - deficiency | CD40 Antigens - deficiency | Atherosclerosis - genetics | CD40 Ligand - blood | Coculture Techniques | Humans | Male | Inflammation - blood | Time Factors | Diet, High-Fat | CD40 Antigens - genetics | Disease Models, Animal | Atherosclerosis - pathology | Signal Transduction | Endothelial Cells - metabolism | Platelet Transfusion | Mice, Inbred C57BL | Cells, Cultured | P-Selectin - genetics | Plaque, Atherosclerotic | Chemotaxis | Mice, Knockout | Atherosclerosis - blood | Platelet Aggregation | Animals | Blood Platelets - metabolism | Apolipoproteins E - genetics | Inflammation - genetics | P-Selectin - blood | CD40 Antigens - blood | Inflammation - prevention & control | Leukocytes - metabolism | Atherosclerosis - prevention & control
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15. Full Text Short-term treatment with atorvastatin reduces platelet CD40 ligand and thrombin generation in hypercholesterolemic patients
by Sanguigni, Valerio and Pignatelli, Pasquale and Lenti, Luisa and Ferro, Domenico and Bellia, Alfonso and Carnevale, Roberto and Tesauro, Manfredi and Sorge, Roberto and Lauro, Renato and Violi, Francesco
Circulation, ISSN 0009-7322, 02/2005, Volume 111, Issue 4, pp. 412 - 419
Background - Soluble CD40L (sCD40L), a substance that maximally reflects in vivo platelet activation, is increased in patients with hypercholesterolemia. We... 
Thrombin | Hypercholesterolemia | Platelet-derived factors | Platelets | Statins | CARDIAC & CARDIOVASCULAR SYSTEMS | thrombin | TISSUE-FACTOR EXPRESSION | RANDOMIZED-TRIAL | ACUTE CORONARY SYNDROMES | platelet-derived factors | platelets | hypercholesterolemia | SOLUBLE CD40L | HEART-DISEASE | STATIN THERAPY | statins | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | PRAVASTATIN | SIMVASTATIN | NF-KAPPA-B | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Hypercholesterolemia - diet therapy | Prothrombin - analysis | CD40 Ligand - blood | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Male | Monocytes - metabolism | Hypercholesterolemia - drug therapy | Multifactorial Inheritance | Thrombin - biosynthesis | Thrombin - pharmacology | Pyrroles - administration & dosage | Fibrinolytic Agents - therapeutic use | Heptanoic Acids - administration & dosage | Female | Collagen - pharmacology | Blood Platelets - drug effects | Pyrroles - therapeutic use | Thromboplastin - biosynthesis | Heptanoic Acids - pharmacology | Hypercholesterolemia - blood | Solubility | Treatment Outcome | Adenosine Diphosphate - pharmacology | Peptide Fragments - analysis | Atorvastatin Calcium | Fibrinolytic Agents - pharmacology | Pyrroles - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Blood Coagulation - drug effects | Blood Platelets - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Biomarkers | Coronary Disease - drug therapy | Fibrinolytic Agents - administration & dosage | Hypercholesterolemia - genetics
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16. Full Text Levels of human platelet-derived soluble CD40 ligand depend on haplotypes of CD40LG-CD40-ITGA2
by Aloui, Chaker and Prigent, Antoine and Tariket, Sofiane and Sut, Caroline and Fagan, Jocelyne and Cognasse, Fabrice and Chakroun, Tahar and Garraud, Olivier and Laradi, Sandrine
Scientific Reports, ISSN 2045-2322, 04/2016, Volume 6, Issue 1, p. 24715
Increased circulating soluble CD40 ligand (sCD40L) is commonly associated with inflammatory disorders. We aimed to investigate whether gene polymorphisms in... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | POLYMORPHISMS | MYOCARDIAL-INFARCTION | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | RISK | ACUTE TRANSFUSION REACTIONS | CD154 GENE | ASSOCIATION | EXPRESSION | SCD40L | Haplotypes | CD40 Ligand - blood | Gene Frequency | Humans | Male | Linkage Disequilibrium | Young Adult | CD40 Ligand - genetics | Integrin alpha2 - genetics | Blood Platelets - metabolism | Adolescent | Alleles | Adult | Female | CD40 Antigens - genetics | Polymorphism, Single Nucleotide | Studies | CD40 antigen | Secretion | Ligands | Platelets | Gene polymorphism | Blood donors
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