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1. Full Text Immune‐reactive soluble OX40 ligand, soluble CD40 ligand, and interleukin‐27 are simultaneously oversecreted in platelet components associated with acute transfusion reactions
by Hamzeh‐Cognasse, Hind and Damien, Pauline and Nguyen, Kim Anh and Arthaud, Charles‐Antoine and Eyraud, Marie‐Ange and Chavarin, Patricia and Absi, Léna and Osselaer, Jean‐Claude and Pozzetto, Bruno and Cognasse, Fabrice and Garraud, Olivier
Transfusion (Philadelphia, Pa.), ISSN 0041-1132, 03/2014, Volume 54, Issue 3, pp. 613 - 625
Life Sciences & Biomedicine | Hematology | Science & Technology | Biological and medical sciences | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis | Transfusions. Complications. Transfusion reactions. Cell and gene therapy | Platelet Transfusion - adverse effects | Blood Platelets - immunology | CD40 Ligand - metabolism | Enzyme-Linked Immunosorbent Assay | Blood Platelets - metabolism | OX40 Ligand - metabolism | Humans | Immunologic Factors - metabolism | Interleukin-27 - metabolism | Thrombin | Transfusion | Interleukins | Blood platelets | Analysis | Cytokines | Medical research | Ligands | Index Medicus
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2. Full Text Soluble CD40 Ligand in Acute Coronary Syndromes
by Heeschen, Christopher and Dimmeler, Stefanie and Hamm, Christian W and van den Brand, Marcel J and Boersma, Eric and Zeiher, Andreas M and Simoons, Maarten L and CAPTURE Study Investigators
The New England journal of medicine, ISSN 0028-4793, 03/2003, Volume 348, Issue 12, pp. 1104 - 1111
Acute Disease | Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors | Prognosis | Follow-Up Studies | Platelet Aggregation Inhibitors/therapeutic use | CD40 Ligand/blood | Humans | Risk Factors | Angina Pectoris/blood/drug therapy | Antibodies, Monoclonal/therapeutic use | Male | Treatment Outcome | Immunoglobulin Fab Fragments/therapeutic use | Biological Markers/blood | Randomized Controlled Trials | Platelet Activation | Middle aged | Research Support, Non-U.S. Gov't | Survival Analysis | Female | Myocardial Infarction/blood/drug therapy | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Heart | Biological and medical sciences | Medical sciences | Coronary heart disease | Myocardial Infarction - blood | CD40 Ligand - blood | Middle Aged | Angina Pectoris - drug therapy | Antibodies, Monoclonal - therapeutic use | Biomarkers - blood | Immunoglobulin Fab Fragments - therapeutic use | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Randomized Controlled Trials as Topic | Angina Pectoris - blood | Myocardial Infarction - drug therapy | Platelet Aggregation Inhibitors - therapeutic use | Physiological aspects | Health aspects | Ligands (Biochemistry) | Heart attack | Risk factors | Cardiovascular disease | Heart attacks | Angina pectoris | Coronary vessels | Index Medicus | Abridged Index Medicus
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3. Full Text Soluble CD40 ligand, platelet surface CD40 ligand, and total platelet CD40 ligand in atrial fibrillation: Relationship to soluble p-selectin, stroke risk factors, and risk factor intervention
by Choudhury, Anirban and Chung, Irene and Panja, Nimai and Patel, Jeetesh and Lip, Gregory Y. H
Chest, ISSN 0012-3692, 2008, Volume 134, Issue 3, pp. 574 - 581
Platelet lysate | Platelet activation | Soluble CD40 | Atrial fibrillation | CD40 ligand | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Heart | Neurology | Cardiac dysrhythmias | Biological and medical sciences | Vascular diseases and vascular malformations of the nervous system | Medical sciences | Pneumology | Atrial Fibrillation - drug therapy | CD40 Ligand - blood | Humans | Middle Aged | Risk Factors | Male | Case-Control Studies | Atrial Fibrillation - blood | Regression Analysis | Blood Platelets - metabolism | Fibrinolytic Agents - therapeutic use | P-Selectin - blood | Female | Stroke - epidemiology | Aged | Cell Membrane - metabolism | Index Medicus | Abridged Index Medicus
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4. Full Text Soluble CD40 ligand contributes to blood–brain barrier breakdown and central nervous system inflammation in multiple sclerosis and neuromyelitis optica spectrum disorder
by Masuda, Hiroki and Mori, Masahiro and Uchida, Tomohiko and Uzawa, Akiyuki and Ohtani, Ryohei and Kuwabara, Satoshi
Journal of neuroimmunology, ISSN 0165-5728, 2016, Volume 305, pp. 102 - 107
Neurology | Allergy and Immunology | Multiple sclerosis | Neuromyelitis optica | Cerebrospinal fluid | Blood-brain barrier | CD40 ligand | Central nervous system | Neurosciences | Immunology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Disability Evaluation | Multiple Sclerosis - blood | Multiple Sclerosis - cerebrospinal fluid | CD40 Ligand - blood | Humans | Middle Aged | Blood-Brain Barrier - physiopathology | Central Nervous System - pathology | Male | Neuromyelitis Optica - pathology | Inflammation | Statistics as Topic | Neuromyelitis Optica - blood | Young Adult | CD40 Ligand - cerebrospinal fluid | Neuromyelitis Optica - cerebrospinal fluid | Interleukin-6 - blood | Statistics, Nonparametric | Multiple Sclerosis - pathology | Adult | Female | Aged | Interleukin-6 - cerebrospinal fluid | Medical colleges | Systemic lupus erythematosus | Interleukins | Albumin | Index Medicus
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5. Full Text Biologically Active CD40 Ligand Is Elevated in Sickle Cell Anemia: Potential Role for Platelet-Mediated Inflammation
by Lee, Sheritha P and Ataga, Kenneth I and Orringer, Eugene P and Phillips, David R and Parise, Leslie V
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 07/2006, Volume 26, Issue 7, pp. 1626 - 1631
CD40L | Inflammation | Sickle cell anemia | Platelets | Coagulation | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Cardiology. Vascular system | Platelet | Blood vessels and receptors | Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous | Atherosclerosis (general aspects, experimental research) | Biological and medical sciences | Blood coagulation. Blood cells | Molecular and cellular biology | Medical sciences | Vertebrates: cardiovascular system | Blood and lymphatic vessels | Cell Proliferation | Anemia, Sickle Cell - complications | CD40 Ligand - blood | Humans | Middle Aged | Monocytes - metabolism | Inflammation - etiology | Case-Control Studies | Hemoglobin, Sickle - metabolism | Intercellular Adhesion Molecule-1 - metabolism | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Blood Platelets - metabolism | Adult | Anemia, Sickle Cell - blood | B-Lymphocytes - pathology | Thromboplastin - metabolism | Thromboplastin - biosynthesis | Index Medicus
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6. Full Text Human CD40 ligand–expressing type 3 innate lymphoid cells induce IL-10–producing immature transitional regulatory B cells
by Komlósi, Zsolt I and Kovács, Nóra and van de Veen, Willem and Kirsch, Anna Isabella and Fahrner, Heinz Benedikt and Wawrzyniak, Marcin and Rebane, Ana and Stanic, Barbara and Palomares, Oscar and Rückert, Beate and Menz, Günter and Akdis, Mübeccel and Losonczy, György and Akdis, Cezmi A
Journal of allergy and clinical immunology, ISSN 0091-6749, 07/2018, Volume 142, Issue 1, pp. 178 - 194.e11
tonsils | Type 3 innate lymphoid cells | immune tolerance | regulatory B cells | allergy | immunoregulation | asthma | immature transitional regulatory B cells | IL-10 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Dendritic cells | B cells | Cell proliferation | CD40 antigen | Mucosa | Differentiation (biology) | Homeostasis | Allergic diseases | Experiments | CD40L protein | Blood | Throat surgery | Peripheral blood | Growth factors | Lymphoid cells | Immunoglobulins | Cell survival | Tonsil | Blood & organ donations | Immunoregulation | Histology | Interleukin 15 | Cell differentiation | Patients | Immunological tolerance | Asthma | Immunosuppression | Lymphocytes B | PD-L1 protein | Interleukin 10 | Ligands | Immunofluorescence
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7. Full Text Dyad of CD40/CD40 ligand fosters neuroinflammation at the blood-brain barrier and is regulated via JNK signaling: Implications for HIV-1 encephalitis
by Ramirez, Servio H and Fan, Shongshan and Dykstra, Holly and Reichenbach, Nancy and Del Valle, Luis and Potula, Raghava and Phipps, Richard P and Maggirwar, Sanjay B and Persidsky, Yuri
The Journal of neuroscience, ISSN 0270-6474, 07/2010, Volume 30, Issue 28, pp. 9454 - 9464
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Humans | JNK Mitogen-Activated Protein Kinases - immunology | Middle Aged | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Monocytes - metabolism | Monocytes - immunology | CD40 Ligand - immunology | Cell Movement - immunology | Signal Transduction - immunology | Inflammation - metabolism | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Flow Cytometry | Adult | Female | HIV-1 - metabolism | Vascular Cell Adhesion Molecule-1 - immunology | Blood-Brain Barrier - immunology | Endothelial Cells - metabolism | Cells, Cultured | Inflammation - immunology | Cell Adhesion - drug effects | AIDS Dementia Complex - immunology | Blotting, Western | Blood-Brain Barrier - metabolism | Cell Adhesion - immunology | Endothelial Cells - immunology | Cell Movement - drug effects | HIV-1 - immunology | AIDS Dementia Complex - metabolism | Analysis of Variance | Signal Transduction - drug effects | CD40 Ligand - pharmacology | Endothelial Cells - cytology | Fluorescent Antibody Technique | Vascular Cell Adhesion Molecule-1 - metabolism | CD40 Antigens - immunology | Index Medicus
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8. Full Text Circulating CD40 ligand, Dickkopf‐1 and P‐selectin in HIV‐infected patients
by Falasca, K and Reale, M and Di Nicola, M and Ucciferri, C and Zecca, IA and Santilli, F and Pontolillo, M and Liani, R and D'Angelo, C and Costantini, E and Vecchiet, J
HIV medicine, ISSN 1464-2662, 11/2019, Volume 20, Issue 10, pp. 681 - 690
P‐selectin | cardiovascular | Dickkopf‐1 | inflammation | CD40 ligand | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Diabetes Mellitus - blood | HIV Infections - blood | CD40 Ligand - blood | Humans | Middle Aged | Male | Biomarkers - blood | Case-Control Studies | Intercellular Signaling Peptides and Proteins - blood | Hypertension - blood | Cardiovascular Diseases - blood | P-Selectin - blood | Adult | Female | Aged | Hypertension | Enzymes | Analysis | HIV patients | Diabetes | HIV (Viruses) | HIV infection | Enzyme-linked immunosorbent assay | CD40 antigen | Diabetes mellitus | Health risks | Population studies | Infections | CD40L protein | Demographics | Human immunodeficiency virus--HIV | Ligands | Cardiovascular diseases | Heart diseases | Index Medicus
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9. Full Text Enhanced Levels of Soluble CD40 Ligand Exacerbate Platelet Aggregation and Thrombus Formation Through a CD40-Dependent Tumor Necrosis Factor Receptor–Associated Factor-2/Rac1/p38 Mitogen-Activated Protein Kinase Signaling Pathway
by Yacoub, Daniel and Hachem, Ahmed and Théorêt, Jean-François and Gillis, Marc-Antoine and Mourad, Walid and Merhi, Yahye
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 12/2010, Volume 30, Issue 12, pp. 2424 - 2433
CD40L | thrombosis | signal transduction | platelets | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Blood Platelets - immunology | Actins - blood | CD40 Ligand - blood | Humans | Male | Blood Platelets - enzymology | Leukocytes - immunology | Neuropeptides - blood | Time Factors | Cell Shape | TNF Receptor-Associated Factor 2 - blood | p38 Mitogen-Activated Protein Kinases - blood | Female | CD40 Antigens - genetics | Thrombosis - blood | Disease Models, Animal | Signal Transduction | Mice, Inbred C57BL | Thrombosis - enzymology | Thrombosis - immunology | Mice, Knockout | Platelet Aggregation | Recombinant Proteins - blood | Animals | rac GTP-Binding Proteins - blood | CD40 Ligand - genetics | CD40 Antigens - blood | rac1 GTP-Binding Protein - blood | Mice | Mutation | Index Medicus
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10. Full Text An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusions
by Blumberg, Neil and Gettings, Kelly F and Turner, Chantal and Heal, Joanna M and Phipps, Richard P
Transfusion (Philadelphia, Pa.), ISSN 0041-1132, 10/2006, Volume 46, Issue 10, pp. 1813 - 1821
Life Sciences & Biomedicine | Hematology | Science & Technology | Fundamental and applied biological sciences. Psychology | Platelet | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care | Transfusions. Complications. Transfusion reactions. Cell and gene therapy | Biological and medical sciences | Intensive care medicine | Blood coagulation. Blood cells | Molecular and cellular biology | Medical sciences | Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis | Hematologic Neoplasms - therapy | Prospective Studies | Cytokines - metabolism | Blood Preservation - adverse effects | Humans | Middle Aged | Blood Preservation - methods | Male | Inflammation - etiology | Leukopenia - therapy | CD40 Ligand - analysis | Platelet Transfusion - adverse effects | Leukopenia - metabolism | Inflammation - metabolism | Blood Platelets - metabolism | Leukopenia - complications | Adult | Female | Aged | Hematologic Neoplasms - complications | Hematologic Neoplasms - metabolism | Index Medicus
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