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Journal Article
Xenotransplantation, ISSN 0908-665X, 01/2018, Volume 25, Issue 1, pp. e12357 - n/a
Background In pig‐to‐human xenotransplantation, interactions between human natural killer (NK) cells and porcine endothelial cells (pEC) are characterized by... 
natural killer cells | human leukocyte antigen‐E/human CD46 | transgenic pigs | xenoperfusion | limb perfusion | release of pig cells | human leukocyte antigen-E/human CD46 | MEDICINE, RESEARCH & EXPERIMENTAL | PROLONGS SURVIVAL | XENOTRANSPLANTATION | COMPLEMENT | ROLLING ADHESION | human CD46 | MODEL | TRANSPLANTATION | G EXPRESSION | XENOGRAFT SURVIVAL | PORCINE ENDOTHELIAL-CELLS | CLASS-I MOLECULES | CYTOTOXICITY | human leukocyte antigen-E | Humans | Histocompatibility Antigens Class I - genetics | HLA Antigens - genetics | Heterografts - immunology | Transplantation, Heterologous - methods | Endothelial Cells - immunology | Animals, Genetically Modified - immunology | Animals | Extremities - blood supply | Leukocytes, Mononuclear - immunology | Killer Cells, Natural - immunology | Membrane Cofactor Protein - genetics | Cytotoxicity, Immunologic - immunology | Leukocytes - metabolism | Membrane Cofactor Protein - immunology | Genetically modified animals | Killer cells | Histocompatibility antigens | Swine | Analysis | HLA histocompatibility antigens | Animal genetic engineering | T cells | Endothelium | Limbs | Flow cytometry | Phenotypes | Cytotoxicity | Leukocytes (mononuclear) | T cell receptors | Lymphocytes T | CD45 antigen | Endothelial cells | Monocytes | CD46 antigen | Immunogenicity | Lymphocytes B | Transgenic animals | Perfusion | Biopsy | Lysis | Xenografts | Peripheral blood mononuclear cells | Histocompatibility antigen HLA | Natural killer cells
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2005, Volume 175, Issue 1, pp. 433 - 440
Neisseria meningitidis is a major cause of sepsis and/or meningitis. These bacteria normally cause disease only in humans, however, mice expressing human CD46... 
NERVOUS-SYSTEM | TUMOR-NECROSIS-FACTOR | PATHOGENIC NEISSERIA | COMPLEMENT ACTIVATION | NEISSERIA-MENINGITIDIS | CELLULAR RECEPTOR | BINDING-PROTEIN | MEASLES-VIRUS | IMMUNOLOGY | MEMBRANE COFACTOR PROTEIN | MENINGOCOCCAL DISEASE | Prostaglandin-Endoperoxide Synthases - biosynthesis | Membrane Glycoproteins - metabolism | Species Specificity | Cyclooxygenase 2 | Humans | Complement C5a - metabolism | Antigens, CD - genetics | Meningitis, Meningococcal - immunology | Antigens, CD - metabolism | Neisseria meningitidis - immunology | Microglia - immunology | Meningitis, Meningococcal - microbiology | Macrophages - immunology | Neutrophils - pathology | Neisseria meningitidis - pathogenicity | Macrophages - pathology | Mice, Inbred C57BL | Neutrophils - immunology | Mice, Transgenic | Membrane Glycoproteins - genetics | Membrane Proteins | Animals | Meningitis, Meningococcal - etiology | Interleukin-6 - biosynthesis | Interleukin-10 - biosynthesis | Mice | Membrane Cofactor Protein | Brain - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Interleukin-6/biosynthesis | Interleukin-10/biosynthesis | Mice; Transgenic | Tumor Necrosis Factor-alpha/biosynthesis | Macrophages/immunology/pathology | Neutrophils/immunology/pathology | Neisseria meningitidis/immunology/pathogenicity | Meningitis; Meningococcal/etiology/immunology/microbiology | Membrane Glycoproteins/genetics/metabolism | Microglia/immunology | Antigens; CD/genetics/metabolism | Prostaglandin-Endoperoxide Synthases/biosynthesis | Brain/immunology | Mice; Inbred C57BL | Complement C5a/metabolism | Research Support; Non-U.S. Gov't | Antigens; CD46
Journal Article
Journal Article
Journal Article
Journal of Medical Microbiology, ISSN 0022-2615, 01/2011, Volume 60, Issue 12, pp. 1860 - 1868
Ankle arthritis was induced by a single subcutaneous (s.c.) infection of 1x107 c.f.u. of the Streptococcus dysgalactiae subspecies equisimilis strain RE378,... 
Animal models | Transgenic mice | Arthritis | Inflammation | Joint diseases | Foot | Ankle | Infection | CD46 antigen | NF- Kappa B protein | Synovial membrane | Tumor necrosis factor | Interleukin 1 | Osteoclasts | Bone loss
Journal Article