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11/2011
Short linear motifs (SLM) play critical roles in cell signaling and are associated with important biochemical events such as phosphorylation, glycosylation,... 
cdk1 | phosphorylation | 0715 | 0306
Dissertation
Cell Cycle, ISSN 1538-4101, 05/2014, Volume 13, Issue 9, pp. 1400 - 1412
Entry and progression through mitosis has traditionally been linked directly to the activity of cyclin-dependent kinase 1 (Cdk1). In this study we utilized low... 
Cdk1 | cyclin B1 | PP2A | SAC | mitosis | RO3306 | Cyclin | Mitosis | Report
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2018, Volume 357, pp. 1 - 9
Diosbulbin B (DB) is the main hepatotoxic compound in Airpotato yam, which is traditionally used for treating thyroid disease and cancer in China, and its... 
CDK1 | Cell Cycle Arrest | miRNA | Hepatotoxicity
Journal Article
SCIENCE, ISSN 0036-8075, 08/2018, Volume 361, Issue 6404, pp. 806 - 809
The cell cycle is strictly ordered to ensure faithful genome duplication and chromosome segregation. Control mechanisms establish this order by dictating when... 
MITOSIS | CELLS | ACTIVATION | MULTIDISCIPLINARY SCIENCES | CDK1 | FOXM1 | REPLICATION STRESS | GENOME
Journal Article
CELL CYCLE, ISSN 1538-4101, 05/2014, Volume 13, Issue 9, pp. 1400 - 1412
Entry and progression through mitosis has traditionally been linked directly to the activity of cyclin-dependent kinase 1 (Cdk1). In this study we utilized low... 
CANCER-CELLS | ACTIVATION | ENTRY | PP2A | SPINDLE ASSEMBLY CHECKPOINT | PROTEIN PHOSPHATASE 2A | GREATWALL KINASE | mitosis | CELL BIOLOGY | CYTOKINESIS | SAC | Cdk1 | cyclin B1 | CELL-CYCLE | RO3306 | EXIT
Journal Article
FEBS Letters, ISSN 0014-5793, 10/2019, Volume 593, Issue 20, pp. 2868 - 2888
Entry into mitosis is triggered by the activation of cyclin‐dependent kinase 1 (Cdk1). This simple reaction rapidly and irreversibly sets the cell up for... 
Cdk1 | Greatwall | Cdc25 | Wee1 | mitosis | cell cycle
Journal Article
Cell Reports, ISSN 2211-1247, 07/2018, Volume 24, Issue 3, pp. 546 - 556
The key mitotic regulator Polo-like kinase 1 (Plk1) is activated during G2 phase by Aurora A kinase (AurkA)-mediated phosphorylation of its activation loop,... 
Plk1 | G2/M transition | WAC | Cyclin A/Cdk1 | mitotic entry | Aurora A | Cyclin B/Cdk1 | MITOSIS | PLK1 ACTIVATION | BORA | PHOSPHORYLATION | POLO-LIKE-KINASE-1 | CDK1 | BOX DOMAIN | AURORA-A | TRCP-DEPENDENT DEGRADATION | REVEALS | CELL BIOLOGY
Journal Article
Cellular Signalling, ISSN 0898-6568, 02/2020, Volume 66, p. 109435
Overexpression of MDM2 oncoprotein has been detected in a large number of diverse human malignancies and has been shown to play both p53-dependent and... 
Nutlin-3 | MDM2 | CDK1 | Aurora Kinase-B | Apoptosis
Journal Article
Theriogenology, ISSN 0093-691X, 01/2020, Volume 142, pp. 158 - 168
SIRT6, a member of the sirtuin family, is a NAD + dependent protein deacetylase and has been implicated in transcriptional regulation of somatic cells and... 
CDK1 | SIRT6 | Meiotic maturation | Oocytes | Pig
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2019, Volume 515, Issue 1, pp. 139 - 144
During cleavage of Xenopus laevis, the first mitotic cell cycle immediately following fertilization is approximately 90 min and consists of S, G2, and M... 
Xenopus | Cdk1 | Cdc25 | Wee1 | Myt1 | Cell cycle | TARGETS CDC25A | ISOFORMS | CDK1 INHIBITORY KINASE | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GOLGI | PHOSPHORYLATES CDC2 | MITOSIS | PLX1 | BIOPHYSICS | PATHWAY | DEGRADATION | Amphibians
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 01/2020, Volume 21, Issue 1, pp. 43 - 51
Resistance to radiation of cancer cells can be either intrinsic or acquired, leading to treatment failure. In response to DNA damage caused by IR, cancer cells... 
CDK1 | cell cycle | Cyclin B1 | radioresistance
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2018, Volume 357, pp. 1 - 9
Diosbulbin B (DB) is the main hepatotoxic compound in Airpotato yam, which is traditionally used for treating thyroid disease and cancer in China, and its... 
CDK1 | Cell Cycle Arrest | miRNA | Hepatotoxicity | Index Medicus
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2016, Volume 1336, pp. 9 - 12
Journal Article
Oncogene, ISSN 0950-9232, 04/2011, Volume 30, Issue 16, pp. 1880 - 1891
Journal Article
Oncotarget, ISSN 1949-2553, 04/2019, Volume 10, Issue 27, p. 2583
The concept of cancer stemness has undergone a paradigm shift during the last decade where there is wider acceptance of the idea that stemness in cancer is a... 
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2020, Volume 521, Issue 1, pp. 252 - 258
To date, the prognosis of multiple myeloma (MM) in patients harboring cytogenetic abnormalities (CA) involving t (4; 14) and deletion of chromosome 17 remains... 
TC11 | Cyclin-dependent kinase 1 (CDK1) | Multiple myeloma | MCL1
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2014, Volume 15, Issue 15, pp. 6437 - 6441
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 12/2019
Ovarian cancer is the most lethal gynecological malignancy, but the mechanisms of ovarian cancer progression and cisplatin resistance remain unclear. Emerging... 
Journal Article
Biology of the Cell, ISSN 0248-4900, 08/2019, Volume 111, Issue 8, pp. 199 - 212
Motile cilia of epithelial multiciliated cells transport vital fluids along organ lumens to promote essential respiratory, reproductive and brain functions.... 
APC/C | Mitosis | Cdk1 | Multiciliated cells | Motile cilia | Differentiation | Centriole | CDK1 ACTIVITY | CENTROSOME SEPARATION | PHOSPHORYLATION | FALLOPIAN-TUBE | CELL BIOLOGY | NUCLEAR-ENVELOPE | EPENDYMAL CELLS | SEROUS OVARIAN-CANCER | APC | CELL-CYCLE | CENTRIOLE AMPLIFICATION | ABNORMAL CILIA
Journal Article