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Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 5893 - 14
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2010, Volume 285, Issue 46, pp. 35932 - 35943
Angiogenesis contributes to various pathological conditions. Due to the resistance against existing antiangiogenic therapy, an urgent need exists to understand... 
NEURONAL MIGRATION | ROSCOVITINE | METASTASIS | CDK5 | PHOSPHORYLATION | ACTIN POLYMERIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOCAL ADHESION KINASE | RHO-GTPASES | CANCER | RAC1 ACTIVITY | Neovascularization, Physiologic - drug effects | Humans | Cell Movement - physiology | Cyclin-Dependent Kinase 5 - genetics | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Microtubules - metabolism | RNA Interference | Chorioallantoic Membrane - drug effects | Female | Phosphorylation - drug effects | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - physiology | Chorioallantoic Membrane - blood supply | Purines - pharmacology | Mice, Inbred C57BL | Umbilical Cord - enzymology | Cells, Cultured | Cell Adhesion | Chick Embryo | Serine - metabolism | Blotting, Western | Cyclin-Dependent Kinase 5 - metabolism | Cell Movement - drug effects | Microscopy, Confocal | Neovascularization, Physiologic - physiology | Cyclin-Dependent Kinase 5 - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Endothelial Cells - cytology | Mice | Protein Kinase Inhibitors - pharmacology | Endothelial Cells - enzymology | Index Medicus | CDK (Cyclin-dependent Kinase) | Protein Kinases | Signal Transduction | Tumor Therapy | Cell Motility | Rho | Cytoskeleton | Confocal Microscopy | Chemotaxis | Cell Biology | Endothelium
Journal Article
Nature Neuroscience, ISSN 1097-6256, 07/2007, Volume 10, Issue 7, pp. 880 - 886
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2019, Volume 510, Issue 3, pp. 370 - 375
Serotonin (5-HT) is a major neurotransmitter in mammalian brains and is involved in brain development and psychiatric disorders. The 5-HT receptor (5-HT R) is... 
Proteasomal degradation | Phosphorylation | Cdk5 | Serotonin | 5-HT | 5-HT1AR | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CDK5 ACTIVATOR P35 | TAG
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2019, Volume 510, Issue 3, pp. 370 - 375
Serotonin (5-HT) is a major neurotransmitter in mammalian brains and is involved in brain development and psychiatric disorders. The 5-HT receptor (5-HT R) is... 
Proteasomal degradation | R | Phosphorylation | Cdk5 | Serotonin | 5-HT
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2018, Volume 504, Issue 4, pp. 753 - 758
Cyclin-dependent kinase 5 (CDK5) is a serine/threonine kinase essential for embryonic development whose overactivation has been implicated in several... 
Cell proliferation | Phosphorylation | Cyclin-dependent kinase (CDK) | Cell migration | NEURONAL MIGRATION | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ORGANIZATION | P35 | BIOPHYSICS | NEURITE OUTGROWTH | CDK5 | PATHWAY | CELL-MIGRATION | DIFFERENTIATION | Embryonic development | Metastasis | Mass spectrometry | Analysis | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1260 - 1260
In order to evaluate the influence of CDK5 inhibitory peptide (CIP) on Human alphaherpesvirus 1 (HSV-1) replication, we constructed two recombinant... 
NEURONAL CELL-CYCLE | P35 | PROTEIN | ACTIVATOR | CDK5 | MULTIDISCIPLINARY SCIENCES | VECTOR
Journal Article
Brain Research Bulletin, ISSN 0361-9230, 06/2017, Volume 132, pp. 28 - 38
Alzheimer’s disease (AD) is one of the most frequently encountered diseases in adults with progressive loss of memory and behavioral changes. Inspite of there... 
Deregulation | Neurofibrillary tangles | Alzheimer’s disease | Cdk5 | Amyloid precursor protein
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e92291 - e92291
Cyclin-dependent kinase 5 (Cdk5)-p35 is a proline-directed Ser/Thr kinase which plays a key role in neuronal migration, neurite outgrowth, and spine formation... 
DENDRITIC SPINE MORPHOGENESIS | COMPLEX | PROTEIN | FILAMENTS | MULTIDISCIPLINARY SCIENCES | CDK5 ACTIVATOR P35 | BIPOLAR TRANSITION | BRAIN-DEVELOPMENT | REGULATES ACTIN POLYMERIZATION | AXONAL GROWTH | CEREBRAL-CORTEX | Phosphotransferases - metabolism | Phosphorylation | Cercopithecus aethiops | Molecular Sequence Data | Substrate Specificity | Neurons - cytology | Dendritic Spines - metabolism | Amino Acid Sequence | Actin Cytoskeleton - metabolism | Gels | Cells, Cultured | Mutant Proteins - metabolism | Neuropeptides - metabolism | Neurites - metabolism | Mutation - genetics | Phosphoserine - metabolism | Mice, Inbred ICR | Cyclin-Dependent Kinase 5 - metabolism | Protein Transport | Animals | Embryo, Mammalian - cytology | Mutant Proteins - chemistry | Neurons - enzymology | Mice | COS Cells | Cell Movement | Neuropeptides - chemistry | Proteins | Brain | Actin | Neurons | Protein binding | Neurosciences | Peptides | Spine | Neurobiology | Science | Proline | Dephosphorylation | Kinases | Cyclin-dependent kinase 5 | Mimicry | Cyclin-dependent kinase | Filaments | Binding | Growth cones | Axonogenesis | Cyclin-dependent kinases | Cortex | Embryos | Substrates | Mutants | Brain research | Mutagenesis | Morphology | Isoforms | Proteomics | Cytoskeleton | Regulation | Protein-serine/threonine kinase | Cell migration | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 2014, Volume 34, Issue 18, pp. 6352 - 6366
Journal Article
NeuroReport, ISSN 0959-4965, 12/2017, Volume 29, Issue 4, pp. 241 - 246
Overactivated cyclin-dependent kinase 5 (Cdk5) induces Golgi fragmentation, which interrupts the processing and trafficking of secretory cargo and subsequently... 
neurotoxicity | cyclin-dependent kinase 5 | Golgi fragmentation | hippocampus | isoflurane | ACTIVATION | ALZHEIMERS-DISEASE | TRAFFICKING | NEURODEGENERATION | NEUROSCIENCES | PROPOFOL | P35 | CDK5 | CHOLECYSTECTOMY | APPARATUS | Usage | Toxicology | Fluorescent antibody technique | Dosage and administration | Research | Electron microscopy | Immunofluorescence | Cyclins | Isoflurane | Golgi apparatus | Index Medicus
Journal Article
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