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Journal Article
Molecular cell, ISSN 1097-2765, 2018, Volume 71, Issue 4, pp. 581 - 591.e5
.... Here, we studied how fluctuations in DNA damage signaling relate to maintenance of long-term cell-cycle arrest... 
systems biology | cell-cycle arrest | signaling dynamics | DNA damage | live-cell imaging | single cells | heterogeneity | p53 | SENESCENCE PROGRAM | CANCER-TREATMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | PROLIFERATION-QUIESCENCE DECISION | DYNAMICS | S-PHASE | HUMAN FIBROBLASTS | SUPPRESSION | EXPRESSION | P21 | CELL BIOLOGY | Gamma Rays | RNA, Small Interfering - genetics | Retinal Pigment Epithelium - metabolism | Epithelial Cells - metabolism | Tumor Suppressor Protein p53 - antagonists & inhibitors | Humans | Green Fluorescent Proteins - genetics | Time-Lapse Imaging | Tumor Suppressor Protein p53 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Cell Cycle Checkpoints - genetics | Retinal Pigment Epithelium - radiation effects | Protein Stability | Epithelial Cells - cytology | Genes, Reporter | Cyclin-Dependent Kinase 2 - metabolism | Green Fluorescent Proteins - metabolism | Epithelial Cells - radiation effects | Signal Transduction | Gene Expression Regulation | Tumor Suppressor Protein p53 - metabolism | Cell Division - radiation effects | Cyclin-Dependent Kinase 2 - genetics | Models, Statistical | Cell Cycle Checkpoints - radiation effects | Luminescent Proteins - genetics | DNA Damage | Cell Line, Transformed | Retinal Pigment Epithelium - cytology | Cell Proliferation - radiation effects | Luminescent Proteins - metabolism | RNA, Small Interfering - metabolism | Tumor proteins | Medical colleges | Cells | Systems biology | cell cycle arrest
Journal Article
Journal Article