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1. Full Text Exosomes
by Pegtel, D. Michiel and Gould, Stephen J
Annual Review of Biochemistry, ISSN 0066-4154, 6/2019, Volume 88, Issue 1, pp. 487 - 514
Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected... 
microvesicle | cell biology | protein trafficking | budding | neurodegeneration | protein oligomerization | cancer | aggregation | immunity | extracellular vesicle | Biochemistry | PROMOTE TUMOR-GROWTH | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLASMA-MEMBRANE | ENDOGENOUS RETROVIRUSES | HEAT-SHOCK PROTEINS | EXTRACELLULAR VESICLES | TRANSFERRIN RECEPTOR | LIPID RAFTS | CANCER EXOSOMES | CELL-DERIVED EXOSOMES | PROTEOMIC ANALYSIS | Cell research
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2. Full Text Biogenesis and secretion of exosomes
by Kowal, Joanna and Tkach, Mercedes and Théry, Clotilde
Current Opinion in Cell Biology, ISSN 0955-0674, 2014, Volume 29, Issue 1, pp. 116 - 125
Highlights • ESCRT proteins, lipids and tetraspanins can independently generate intraluminal vesicles. • Different RAB proteins can target multivesicular... 
Internal Medicine | MULTIVESICULAR BODIES | RETICULOCYTE MATURATION | TRANSFERRIN RECEPTOR | ALIX | RNA | VESICLES | MICROVESICLES | CELL-DERIVED EXOSOMES | PROTEINS | DISTINCT POPULATIONS | CELL BIOLOGY | Cell Membrane - metabolism | Animals | Biological Transport | Humans | Exosomes - secretion | Proteins
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3. Full Text Exosomes – vesicular carriers for intercellular communication
by Simons, Mikael and Raposo, Graça
Current Opinion in Cell Biology, ISSN 0955-0674, 2009, Volume 21, Issue 4, pp. 575 - 581
Cells release different types of vesicular carriers of membrane and cytosolic components into the extracellular space. These vesicles are generated within the... 
Internal Medicine | MULTIVESICULAR BODIES | DENDRITIC CELLS | RETICULOCYTE MATURATION | K562 CELLS | TRAFFICKING | PEPTIDE COMPLEXES | SECRETION | CELL-DERIVED EXOSOMES | PROTEINS | PLASMA-MEMBRANE | CELL BIOLOGY | Exosomes - metabolism | Humans | Gene Expression Regulation | Cell Communication | Endosomes - metabolism | Protein Transport | Animals | Dictyostelium | Nucleic Acids - chemistry | Models, Biological | Cytoplasmic Vesicles - metabolism | Cytosol - metabolism | Cell Membrane - metabolism | Organelles - metabolism | Physiological aspects | Nucleic acids
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4. Full Text Pharmacokinetics of Exosomes—An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics
by Morishita, Masaki and Takahashi, Yuki and Nishikawa, Makiya and Takakura, Yoshinobu
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 09/2017, Volume 106, Issue 9, pp. 2265 - 2269
Exosomes are small membrane vesicles containing lipids, proteins, and nucleic acids. Recently, researchers have uncovered that exosomes are involved in various... 
pharmacokinetics | therapeutics | exosomes | biological functions | CANCER-CELLS | CHEMISTRY, MEDICINAL | BIODISTRIBUTION | MEDIATED TRANSFER | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | MESENCHYMAL STROMAL CELLS | B16BL6-DERIVED EXOSOMES | INTRAVENOUS-INJECTION | EXTRACELLULAR VESICLES | KIDNEY INJURY | PHARMACOLOGY & PHARMACY | CELL-DERIVED EXOSOMES | Exosomes - metabolism | Tissue Distribution - physiology | Pharmaceutical Preparations - metabolism | Animals | Drug Delivery Systems - methods | Humans
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5. Full Text Separation of plasma‐derived exosomes into CD3(+) and CD3(–) fractions allows for association of immune cell and tumour cell markers with disease activity in HNSCC patients
by Theodoraki, M.‐N and Hoffmann, T. K and Whiteside, T. L
Clinical & Experimental Immunology, ISSN 0009-9104, 06/2018, Volume 192, Issue 3, pp. 271 - 283
Summary Head and neck squamous cell carcinoma (HNSCC) is a highly immunosuppressive malignancy. Exosomes in HNSCC patients' plasma are enriched in inhibitory... 
tumour‐derived exosomes (TEX) | disease progression | T cell‐derived exosomes | HNSCC | immune regulation | tumour-derived exosomes (TEX) | T cell-derived exosomes | HEAD | MELANOMA | REGULATORY T-CELLS | CANCER EXOSOMES | IMMUNOLOGY | EXPRESSION | COX-2 inhibitors | Squamous cell carcinoma | Analysis | Immunotherapy | Development and progression | T cells | Tumor proteins | Tumors | Enrichment | Plasma | Flow cytometry | CD8 antigen | Antibodies | Cytotoxicity | Lymphocytes T | Malignancy | Exosomes | Prostaglandin endoperoxide synthase | Proteins | Lymphocytes | Head | Immunostimulation | Immunoregulation | CD3 antigen | T cell receptors | Disease control | Patients | Molecular chains | CD4 antigen | Immunosuppression | Ox40L protein | Tumor necrosis factor | Biomarkers | Head and neck cancer | Cancer | Apoptosis | Original
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6. Full Text ExosomesSmall Players, Big Sound
by Gulei, Diana and Irimie, Alexandra Iulia and Cojocneanu-Petric, Roxana and Schultze, Joachim L and Berindan-Neagoe, Ioana
Bioconjugate Chemistry, ISSN 1043-1802, 03/2018, Volume 29, Issue 3, pp. 635 - 648
Incipiently named extracellular vesicles, exosomes are forming now a separate class of cellular mediators with important functions in physiological and... 
CANCER-CELLS | CARCINOEMBRYONIC-ANTIGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | MATURE DENDRITIC CELLS | CHEMISTRY, MULTIDISCIPLINARY | DRUG-DELIVERY VEHICLES | IN-VITRO | TRANSFERRIN RECEPTOR | COLORECTAL-CANCER | VESICLE FORMATION | CELL-DERIVED EXOSOMES | STROMAL CELLS | Immunologic Factors - chemistry | Immunotherapy - methods | Humans | Cell Fractionation - methods | Immunologic Factors - immunology | Exosomes - pathology | MicroRNAs - immunology | Immunity | Cancer Vaccines - immunology | Cancer Vaccines - therapeutic use | Neoplasms - therapy | Animals | Neoplasms - immunology | Exosomes - immunology | Exosomes - chemistry | Neoplasms - pathology | Drug Delivery Systems - methods | MicroRNAs - chemistry
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7. Full Text Exosomes in developmental signalling
by McGough, Ian John and Vincent, Jean-Paul
Development (Cambridge), ISSN 0950-1991, 07/2016, Volume 143, Issue 14, pp. 2482 - 2493
In order to achieve coordinated growth and patterning during development, cells must communicate with one another, sending and receiving signals that regulate... 
Hedgehog | Exosomes | Signalling | WNT | DROSOPHILA ORTHOLOG | ESCRT-III | RETICULOCYTE MATURATION | LONG-RANGE ACTIVITY | CHOLESTEROL MODIFICATION | DEVELOPMENTAL BIOLOGY | EXTRACELLULAR VESICLES | TRANSFERRIN RECEPTOR | MEDIATED ENDOCYTOSIS | CELL-DERIVED EXOSOMES | SONIC-HEDGEHOG | Carcinogenesis - pathology | Exosomes - metabolism | Animals | Signal Transduction | Models, Biological | Humans | Cell Membrane - metabolism | Growth and Development | Carcinogenesis - metabolism
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8. Full Text Extracellular vesicles: Exosomes, microvesicles, and friends
by Raposo, G and Stoorvogel, W
Journal of Cell Biology, ISSN 0021-9525, 2013, Volume 200, Issue 4, pp. 373 - 383
Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles,... 
International (English) | ENDOSOMAL SORTING COMPLEX | CALCIUM-DEPENDENT MANNER | DENDRITIC CELLS | MULTIVESICULAR BODIES | MEMBRANE-VESICLES | ENDOTHELIAL-CELLS | CELL-DERIVED EXOSOMES | PROTEOMIC ANALYSIS | LIPOPROTEIN PARTICLES | TETRASPANIN PROTEINS | CELL BIOLOGY | Proteins - metabolism | Membrane Fusion | Models, Biological | Exosomes - physiology | Cell Communication | Biological Transport - physiology | Cell Membrane - metabolism | Cell Membrane - ultrastructure | Exosomes - ultrastructure | Physiological aspects | Cell organelles | Research | Properties | Molecular biology | Reviews
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9. Full Text Exosomes: A novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions
by Zhang, Huang-Ge and Grizzle, William E
American Journal of Pathology, ISSN 0002-9440, 2014, Volume 184, Issue 1, pp. 28 - 41
Normal and diseased cells release bilayered membrane-bound nanovesicles into interstitial spaces and into bodily fluids. A subgroup of such microvesicles is... 
MESSENGER-RNAS | TUMOR-RELEASED MICROVESICLES | DENDRITIC CELLS | IMMUNE-RESPONSES | PROSTATE-CANCER | SUPPRESSOR-CELLS | INDUCE APOPTOSIS | PATHOLOGY | CELL-DERIVED EXOSOMES | PROTEOMIC ANALYSIS | PEPTIDE-BASED VACCINE | Neoplasms - metabolism | Exome - physiology | Animals | Neoplasms - pathology | Humans | Review
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10. Full Text Exosomes: Extracellular organelles important in intercellular communication
by Mathivanan, Suresh and Ji, Hong and Simpson, Richard J
Journal of Proteomics, ISSN 1874-3919, 2010, Volume 73, Issue 10, pp. 1907 - 1920
In addition to intracellular organelles, eukaryotic cells also contain extracellular organelles that are released, or shed, into the microenvironment. These... 
Extracellular vesicles | Biomarkers | Microvesicles | Shedding microvesicles | Exosomes | Apoptotic blebs | DENDRITIC CELLS | COMPLEX CLASS-II | BIOCHEMICAL RESEARCH METHODS | HUMAN A33 ANTIGEN | ACTIVATED PLATELETS | GEL-ELECTROPHORESIS | BIOLOGICAL SIGNIFICANCE | TISSUE-FACTOR | MULTIVESICULAR BODIES | CELL-DERIVED EXOSOMES | PROTEOMIC ANALYSIS
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11. Full Text Exosomes and tumor-mediated immune suppression
by Whiteside, Theresa L
Journal of Clinical Investigation, ISSN 0021-9738, 04/2016, Volume 126, Issue 4, pp. 1216 - 1223
Tumor-derived exosomes (TEX) are harbingers of tumor-induced immune suppression: they carry immunosuppressive molecules and factors known to interfere with... 
MEDICINE, RESEARCH & EXPERIMENTAL | FAS LIGAND | EXTRACELLULAR VESICLES | DENDRITIC CELLS | PROSTATE-CANCER | PANCREATIC-CANCER | MICROVESICLES | T-CELL | INDUCE APOPTOSIS | CELL-DERIVED EXOSOMES | NECK-CANCER | RNA, Messenger - immunology | Humans | Immune Tolerance | Exosomes - pathology | RNA, Neoplasm - immunology | MicroRNAs - immunology | Signal Transduction - immunology | Animals | Neoplasms - immunology | Exosomes - immunology | DNA, Neoplasm - immunology | Neoplasms - pathology | Biomarkers, Tumor - immunology | Immunity, Cellular | Immune response | Cell organelles | Genetic aspects | Cellular signal transduction | Regulation | Health aspects | Carcinogenesis | Studies | Body fluids | Plasma | Cytokines | Lymphocytes | Biomarkers | Ligands | Gene expression | Cancer | Apoptosis
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12. Full Text Q&A: What are exosomes, exactly?
by Edgar, JR
BMC BIOLOGY, ISSN 1741-7007, 06/2016, Volume 14, Issue 1, p. 46
Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell-cell communication and the transmission of disease... 
TRANSFERRIN RECEPTOR | BIOGENESIS | MECHANISM | VESICLES | BIOLOGY | RELEASE | RETICULOCYTES | MICRORNAS | SECRETION | CELL-DERIVED EXOSOMES | ASSOCIATION | Biomarkers - metabolism | Exosomes - metabolism | Animals | Disease | Models, Biological | Humans | Exosomes - ultrastructure | Physiological aspects | Extracellular matrix | Cellular biology
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