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06/2013
B lymphocytes develop from pluripotent stem cells, and differentiate to plasma cells (PCs) in reaction to signals from the supportive microenvironment.... 
0982 | B cell development
Dissertation
06/2012
B lymphopoiesis is regulated by cytokines, chemokines and cell surface proteins that initiate signal transduction pathways necessary for maturation to proceed.... 
0982 | B Cell Development
Dissertation
11/2013
BLNK is an adaptor protein that functions in B-cell receptor signalling, and is vitally necessary at signalling checkpoints of mammalian B-cell development.... 
B-cell development | 0982 | BLNK
Dissertation
11/2012
A common bipotent thymocyte precursor gives rise to both lineages of T cells, αβ and γδ. This thesis addresses how the interplay between intrinsic T cell... 
T cell development | Notch signaling | 0982
Dissertation
BLOOD, ISSN 0006-4971, 06/2019, Volume 133, Issue 24, pp. 2557 - 2558
In this issue of Blood, Yin et al demonstrated that engineered BCL6 interacting corepressor protein (Bcor) mutation in hematopoietic stem/progenitor cells of... 
B-CELL DEVELOPMENT | HEMATOLOGY
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 04/2014, Volume 15, Issue 4, pp. 393 - 393
The microRNA miR-210 is a signature of hypoxia. We found robust increase in the abundance of miR-210 (>100-fold) in activated T cells, especially in the T(H)17... 
SYSTEM | INDUCIBLE FACTORS | RESPONSES | ACTIVATION | CYTOKINES | COMPLEX | TARGETS | IMMUNOLOGY | T-CELL DEVELOPMENT | CANCER | PREDICTION
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 07/2010, Volume 107, Issue 29, pp. 13022 - 13027
Whereas humanized mouse models have contributed significantly to human immunology research, human T cells developing in mouse thymic environment fail to... 
Human immunology | HLA restriction | Epstein-Barr virus | T-cell development | Biological Sciences | human immunology | Epstein–Barr virus
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 06/2018, Volume 141, Issue 6, pp. 2168 - 2181
Allergic asthma is one of the most common diseases worldwide, resulting in a burden of diseases. No available therapeutic regimens can cure asthma thus far. We... 
Allergy | Wip1 | phosphatase | TH9 cell development | IL-9 | 9 cell development
Journal Article
2011, Advances in plant biology, ISBN 1441909877, Volume 2
Web Resource
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 09/2018, Volume 115, Issue 38, p. E8873
The Ciona notochord has emerged as a simple and tractable in vivo model for tubulogenesis. Here, using a chemical genetics approach, we identified UTKO1 as a... 
Physiological aspects | Cell research | Research | Cell development (Biology) | Notochord
Journal Article
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7679
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 01/2018, Volume 38, Issue 1
Recombination activating gene 1 (RAG1) and RAG2 are critical enzymes for initiating variable-diversity-joining [V(D)J] segment recombination, an essential... 
RAG | Bcl11a | Immunology | B cell development | V(D)J
Journal Article
Fungal Genetics and Biology, ISSN 1087-1845, 11/2019, Volume 132, p. 103264
Agmatinase is known as a metalloenzyme which hydrolyzes agmatine to produce urea and putrescine, being crucial in the alternative pathway to produce... 
Cell development | N. crassa | Agmatinase | Polyamines | Actin | Agmatine
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 07/2017, Volume 18, Issue 7, pp. 771 - 771
TCR alpha b(+)CD4(-)CD8 alpha(+)CD8 beta-intestinal intraepithelial lymphocytes (CD8 alpha alpha IELs) are an abundant population of thymus-derived T cells... 
MIGRATION | INKT CELLS | TRAFFICKING | PROGENITOR LOCALIZATION | CYTOMETRY | IMMUNOLOGY | T-CELL DEVELOPMENT | THYMOCYTES | SELECTION | RECEPTORS | LINEAGE
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2015, Volume 125, Issue 8, p. 2995
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 08/2019, Volume 20, Issue 17, p. 4179
Over the past two decades, studies have demonstrated that several features of T-cell and thymic development are conserved from teleosts to mammals. In... 
zebrafish | T-cell development | thymopoiesis | medaka | imaging
Journal Article
2013, Methods in molecular biology, ISBN 9781627032216, Volume 959.
Web Resource
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