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11/2012
In order to elucidate how uncoupling protein 2 (UCP2) influences pancreatic β cells and glucose homeostasis, I have generated and characterized an inducible β... 
beta-cell function | 0719 | Physiology | Diabetes | Endocrinology
Dissertation
2015, Fundamentals of biomedical science, ISBN 9780199652471, xvi, 500
Book
2017, Advances in experimental medicine and biology, ISBN 3319571273, Volume 1002., xiv, 235 pages
This volume critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the... 
Cell proliferation | Cell division | Oncology | Pathology, Cellular
Book
Journal of diabetes investigation, ISSN 2040-1116, 06/2019
We investigated associations between glucose tolerance and beta-cell function using a series of estimation methods in a population-based study. Data from the... 
Journal Article
Journal Article
by Lee, I
PANCREAS, ISSN 0885-3177, 03/2018, Volume 47, Issue 3, pp. e6 - e7
Journal Article
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, ISSN 0021-972X, 10/2014, Volume 99, Issue 10, pp. 3551 - 3560
Context: Observational studies report consistent associations between low vitamin D concentration and increased glycemia and risk of type 2 diabetes, but... 
INSULIN-RESISTANCE | BLOOD-GLUCOSE | D-DEFICIENT | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | WEIGHT-LOSS | RANDOMIZED CONTROLLED-TRIAL | PLACEBO-CONTROLLED TRIAL | ENDOTHELIAL FUNCTION | CARDIOVASCULAR RISK-FACTORS | BETA-CELL FUNCTION
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, p. 12814
The mechanical wiring between cells and their surroundings is fundamental to the regulation of complex biological processes during tissue development, repair... 
MIGRATION | TRANSMISSION | PLASMONICS | MULTIDISCIPLINARY SCIENCES | HIGH-RESOLUTION | CELL-FUNCTION | FIBROBLASTS | THICKNESS | FOCAL ADHESIONS | MECHANOTRANSDUCTION | STRESSES
Journal Article
2017, Advances in experimental medicine and biology, ISBN 3319553305, Volume 982., ix, 618 pages
This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology... 
Cardiovascular system | Mitochondrial Dynamics | Mitochondrial pathology | Cardiovascular Diseases | physiopathology | Molecular aspects | Diseases | Metabolic diseases
Book
11/2012
Emerging evidence suggests that vitamin D may be associated with type 2 diabetes (T2DM), however current data are inconsistent regarding metabolic disorders... 
Beta-cell Function | Vitamin D | Type 2 Diabetes | Metabolic Syndrome | Insulin Resistance | 0570
Dissertation
American journal of physiology, ISSN 0363-6143, 1977
Journal
Journal of cellular physiology, ISSN 0021-9541, 1966
Journal
2015, 1st ed. 2015, Advances in experimental medicine and biology, ISBN 3319237306, Volume 889, xi, 235
This volume thoroughly explores of the functional role of microRNAs in cancer. It not only expertly describes the molecular mechanisms underlying the malignant... 
physiopathology | Tumor markers | MicroRNAs | Small interfering RNA | physiology | Genetic aspects | Genetic regulation | Non-coding RNA | Neoplasms | Cancer | RNA, Neoplasm | Cell Physiology | Cancer Research | Molecular Medicine | Biomedicine | Human Physiology | Animal Biochemistry
Book
2015, 1st ed. 2015, Advances in experimental medicine and biology, ISBN 3319226703, Volume 888, xii, 429
This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using... 
Small interfering RNA | physiology | therapeutic use | MicroRNAs | Cell Physiology | Atomic/Molecular Structure and Spectra | Molecular Medicine | Biomedicine | Human Physiology | Animal Biochemistry | RNA | Medical genetics
Book
2015, 1st ed. 2015, Advances in experimental medicine and biology, ISBN 3319223798, Volume 887., xiii, 257
This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine... 
genetics | MicroRNAs | Epigenesis, Genetic | Antisense RNA | Molecular Targeted Therapy | Non-coding RNA | RNA, Neoplasm | Life Sciences | Cell Physiology | Atomic/Molecular Structure and Spectra | Molecular Medicine | Human Physiology | Animal Biochemistry | Small interfering RNA
Book
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 03/2007, Volume 178, Issue 5, pp. 2623 - 2629
Universal and essential to cytokine receptor signaling, the JAK-STAT pathway is one of the best understood signal transduction cascades. Almost 40 cytokine... 
INTERFERON-GAMMA | CELL FUNCTION | TYROSINE KINASE | CYTOKINE SIGNALING-1 | ERYTHROPOIETIN RECEPTOR | IN-VIVO | EMERGENCY GRANULOPOIESIS | GENE-EXPRESSION | IMMUNOLOGY | ANTIINFLAMMATORY RESPONSE | NEGATIVE REGULATOR
Journal Article
DIABETES, ISSN 0012-1797, 08/2012, Volume 61, Issue 8, pp. 2066 - 2073
Interpretation of clinical trials to alter the decline in beta-cell function after diagnosis of type 1 diabetes depends on a robust understanding of the... 
INSULIN | THERAPY | ANTI-CD3 MONOCLONAL-ANTIBODY | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | RISK | TOLERANCE-TEST | MELLITUS | NATURAL-HISTORY | ONSET | BETA-CELL FUNCTION
Journal Article
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