X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
cellcycle (956) 956
cell biology (802) 802
animals (511) 511
humans (507) 507
biochemistry & molecular biology (483) 483
mice (345) 345
oncology (300) 300
molecular biology (286) 286
cancer research (284) 284
cancer (217) 217
biochemistry, genetics and molecular biology (211) 211
dna (205) 205
proteins (203) 203
signaling (181) 181
phosphorylation (175) 175
apoptosis (163) 163
cell line, tumor (161) 161
cellbio (159) 159
cell cycle proteins - metabolism (147) 147
agricultural and biological sciences (126) 126
analysis (125) 125
protein (124) 124
expression (116) 116
activation (110) 110
developmental biology (110) 110
signal transduction (108) 108
mutation (105) 105
female (102) 102
cell line (101) 101
protein-serine-threonine kinases - metabolism (100) 100
cell proliferation (98) 98
models, biological (97) 97
protein binding (96) 96
cells, cultured (90) 90
dna-binding proteins - metabolism (88) 88
molecular sequence data (88) 88
research (88) 88
cell cycle (86) 86
hela cells (86) 86
oncology, experimental (86) 86
amino acid sequence (78) 78
in-vivo (77) 77
tumors (77) 77
mice, knockout (76) 76
saccharomyces cerevisiae proteins - metabolism (76) 76
male (73) 73
rna interference (72) 72
growth (71) 71
saccharomyces-cerevisiae (71) 71
gene-expression (70) 70
mitosis (69) 69
nuclear proteins - metabolism (69) 69
identification (68) 68
cells (67) 67
tumor suppressor protein p53 - metabolism (67) 67
dna damage (66) 66
protein structure, tertiary (66) 66
cell cycle proteins - genetics (60) 60
gene expression regulation, neoplastic (59) 59
transcription factors - metabolism (59) 59
cell-cycle (58) 58
gene (58) 58
mice, inbred c57bl (57) 57
mice, transgenic (57) 57
rna (56) 56
tumor proteins (56) 56
drosophila (55) 55
enzyme activation (55) 55
complex (54) 54
gene expression profiling (54) 54
stemcell (54) 54
saccharomyces cerevisiae - metabolism (53) 53
time factors (52) 52
devbio (51) 51
gene expression (51) 51
humdisease (51) 51
transfection (51) 51
apoptosis - physiology (50) 50
kinase (50) 50
protein kinases - metabolism (50) 50
genetic aspects (48) 48
genetic research (48) 48
models, molecular (48) 48
transcription, genetic (48) 48
breast-cancer (46) 46
pathway (45) 45
saccharomyces cerevisiae proteins - genetics (44) 44
spindle apparatus - metabolism (44) 44
apoptosis - drug effects (43) 43
drosophila proteins - metabolism (43) 43
nuclear proteins - genetics (43) 43
saccharomyces cerevisiae - genetics (43) 43
ubiquitin (43) 43
binding (42) 42
signal transduction - physiology (42) 42
budding yeast (41) 41
dna-binding proteins - genetics (41) 41
tumor suppressor protein p53 - genetics (41) 41
chromatin (40) 40
degradation (40) 40
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cancer cell, ISSN 1535-6108, 2009, Volume 16, Issue 3, pp. 195 - 207
ErbB2, a metastasis-promoting oncoprotein, is overexpressed in ∼25% of invasive/metastatic breast cancers, but in 50%–60% of noninvasive ductal carcinomas... 
CELLCYCLE
Journal Article
Molecular cell, ISSN 1097-2765, 2007, Volume 27, Issue 3, pp. 462 - 473
During the G1/S transition, p21 proteolysis is mediated by Skp2; however, p21 reaccumulates in G2 and is degraded again in prometaphase. How p21 degradation is... 
PROTEINS | CELLCYCLE
Journal Article
Molecular cell, ISSN 1097-2765, 2009, Volume 34, Issue 6, pp. 663 - 673
In response to oxidative stress, Nrf2 and p21 are both upregulated to protect cells from oxidative damage. Nrf2 is constantly ubiquitinated by a Keap1 dimer... 
PROTEINS | CELLCYCLE | SIGNALING
Journal Article
Molecular cell, ISSN 1097-2765, 2009, Volume 34, Issue 3, pp. 271 - 284
The p16 tumor suppressor gene is a frequent target of epigenetic inactivation in human cancers, which is an early event in breast carcinogenesis. We describe... 
CELLCYCLE | DNA | HUMDISEASE
Journal Article
Cancer cell, ISSN 1535-6108, 10/2007, Volume 12, Issue 4, pp. 313 - 327
Although TGFβ is a potent inhibitor of proliferation, epithelia lacking the essential receptor (TβRII) for TGFβ signaling display normal tissue homeostasis. By... 
CELLCYCLE | DEVBIO
Journal Article
Cancer cell, ISSN 1535-6108, 2010, Volume 17, Issue 2, pp. 121 - 134
Chronically activated leukocytes recruited to premalignant tissues functionally contribute to cancer development; however, mechanisms underlying pro- versus... 
CELLCYCLE | MOLIMMUNO | CELLIMMUNO | PRIMARY TUMORS | ANGIOGENESIS | ONCOLOGY | MACROPHAGES | MAST-CELLS | TIE2-EXPRESSING MONOCYTES | GROWTH | HUMORAL IMMUNITY | K14-HPV16 TRANSGENIC MICE | RECEPTORS | CANCER
Journal Article
Cancer cell, ISSN 1535-6108, 2009, Volume 15, Issue 4, pp. 283 - 293
NF-κB (RelA) is constitutively active in many cancers, where it upregulates antiapoptotic and other oncogenic genes. While proinflammatory stimulus-induced... 
CELLCYCLE | CELLS | ONCOLOGY | ACETYLATION | PHOSPHORYLATION | IMMUNE-RESPONSES | COLITIS-ASSOCIATED CANCER | GROWTH-FACTOR | TRANSCRIPTION FACTOR | LINKS INFLAMMATION | IL-6 | SIGNAL TRANSDUCER | CELL BIOLOGY
Journal Article
Cancer cell, ISSN 1535-6108, 2009, Volume 15, Issue 2, pp. 103 - 113
Colitis-associated cancer (CAC) is the most serious complication of inflammatory bowel disease. Proinflammatory cytokines have been suggested to regulate... 
CELLCYCLE | COLON-CANCER | BACTERIAL PATHOGENS | INFLAMMATORY-BOWEL-DISEASE | TGF-BETA | ONCOLOGY | DESIGNER CYTOKINE | COLORECTAL-CANCER | MOUSE MODEL | ULCERATIVE-COLITIS | NF-KAPPA-B | GP130 MUTANT MICE | Phorbol esters | Universities and colleges | Interleukins | Gastrointestinal diseases | Cancer
Journal Article
Developmental cell, ISSN 1534-5807, 2009, Volume 16, Issue 6, pp. 856 - 866
Xenopus oocyte death is partly controlled by the apoptotic initiator caspase-2 (C2). We reported previously that oocyte nutrient depletion activates C2... 
CELLBIO | CELLCYCLE | 14-3-3 | glucose-6-phosphate | oocyte | caspase-2 | protein phosphatase-1
Journal Article
Cancer cell, ISSN 1535-6108, 2010, Volume 17, Issue 4, pp. 319 - 332
High Gleason grade prostate carcinomas are aggressive, poorly differentiated tumors that exhibit diminished estrogen receptor β (ERβ) expression. We report... 
CELLCYCLE | DNA | SIGNALING | ESTROGEN-RECEPTOR-BETA | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | CARCINOMA-CELLS | RECENT TRENDS | ONCOLOGY | E-CADHERIN EXPRESSION | ALPHA | TUMOR-CELLS | TRANSCRIPTIONAL REPRESSOR | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Cancer cell, ISSN 1535-6108, 2010, Volume 18, Issue 1, pp. 74 - 87
Although Bcr-Abl kinase inhibitors have proven effective in the treatment of chronic myeloid leukemia (CML), they generally fail to eradicate Bcr-Abl +... 
CELLCYCLE
Journal Article
Cancer cell, ISSN 1535-6108, 2010, Volume 17, Issue 1, pp. 89 - 97
Chronic exposure to tobacco smoke, which contains over 60 tumor-initiating carcinogens, is the major risk factor for development of lung cancer, accounting for... 
CELLCYCLE | MOLIMMUNO | CELLIMMUNO | A/J MOUSE | CELLS | ONCOLOGY | RAS | BIOCHEMISTRY | CARCINOGENICITY | COLITIS-ASSOCIATED CANCER | CIGARETTE-SMOKE | MICE | NF-KAPPA-B | INNATE IMMUNITY
Journal Article
Cancer cell, ISSN 1535-6108, 2009, Volume 15, Issue 5, pp. 416 - 428
The increased motility and invasiveness of tumor cells are reminiscent of epithelial-mesenchymal transition (EMT), which occurs during embryonic development,... 
CELLCYCLE | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | MAMMARY-TUMORS | ONCOLOGY | REPRESSOR SNAIL | COP9 SIGNALOSOME | TUMOR-METASTASIS | TRANSCRIPTION FACTOR SNAIL | GENE-EXPRESSION | E-CADHERIN | UBIQUITIN LIGASES
Journal Article
Molecular cell, ISSN 1097-2765, 07/2007, Volume 27, Issue 2, pp. 214 - 227
We recently reported that a large proportion of aggressive squamous cell carcinomas of humans and mice express markedly reduced IKKα. However, the role of IKKα... 
CELLCYCLE | SIGNALING
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2009, Volume 139, Issue 4, pp. 693 - 706
Inflammation is linked clinically and epidemiologically to cancer, and NF-κB appears to play a causative role, but the mechanisms are poorly understood. We... 
CELLCYCLE | HUMDISEASE | SURVIVAL | BREAST-CANCER CELLS | ACTIVATION | RAS | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | STAT3 | MECHANISMS | TUMORIGENESIS | EXPRESSION | IN-VITRO PROPAGATION | CELL BIOLOGY | NF-κB | IL6 | cellular transformation | let-7 | inflammation | cancer | positive feedback loop | epigenetics | Lin 28
Journal Article