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Current Opinion in Cell Biology, ISSN 0955-0674, 10/2019, Volume 60, pp. 92 - 98
Through phase separation, some proteins form liquid-like condensates or droplets which can flow, fuse, and even deform when pressure is applied. In some cases,... 
TRANSITION | ELEGANS REQUIRE | BUB3 STABILITY | AURORA-A KINASE | PHOSPHORYLATION | SPINDLE APPARATUS | COACERVATION | BIOLOGY | CENTROSOME MATURATION | CELL | CELL BIOLOGY | Proteins
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 11/2018, Volume 430, Issue 23, pp. 4762 - 4772
Cells compartmentalize biochemical reactions using organelles, which can be membrane enclosed or built entirely of proteins and ribonucleic acids. Recent... 
gelation | centrosomes | phase separation | mitosis | spindle matrix | CENTROSOME SIZE | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERICENTRIOLAR MATERIAL | LIQUID DROPLETS | MICROTUBULE NUCLEATION | PUTATIVE SPINDLE MATRIX | CELL | GAMMA-TUBULIN | Tubulins | Chromosomes | Cells
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 6, pp. 538 - 549
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 08/2019, Volume 29, Issue 8, pp. 612 - 622
There is currently intense interest in the idea that many membraneless organelles might assemble through phase separation of their constituent molecules into... 
phase separation | cell division | PCM | centrosome | centriole | mitosis | biomolecular condensates | CAENORHABDITIS-ELEGANS | HAMSTER OVARY CELLS | ASSEMBLY PATHWAY | CNN SCAFFOLD | MITOTIC CENTROSOME | CENTRIOLE CYCLE | MICROTUBULE NUCLEATION | PERICENTRIN-LIKE-PROTEIN | AURORA-A | GAMMA-TUBULIN | CELL BIOLOGY | Proteins | Analysis | Cells | Constituents | Molecular structure | Condensates | Organelles | Phase separation | Centrosomes
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 11/2018, Volume 430, Issue 23, pp. 4806 - 4820
The formation of membrane-less organelles and compartments by protein phase separation is an important way in which cells organize their cytoplasm and... 
membrane-less compartment | phase separation | protein purification | Sup35 | low-complexity proteins | membrane-less organelle | prion-like protein | RNA INTERFERENCE | CENTROSOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPONENTS | DETERMINANT | LIQUID DROPLETS | GERM GRANULES | PRION | TRANSITION | P GRANULES | STRESS | Proteins | Fluorescence | Cells | Sugars | Protein binding
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 02/2012, Volume 23, Issue 3, pp. 401 - 411
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2011, Volume 30, Issue 13, pp. 2634 - 2647
The NIMA‐family kinases Nek9/Nercc1, Nek6 and Nek7 form a signalling module required for mitotic spindle assembly. Nek9, the upstream kinase, is activated... 
Eg5 | kinase | Plk1 | centrosome | Nek | NIMA-FAMILY KINASE | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLO | MITOTIC SPINDLE FORMATION | CELL BIOLOGY | MITOSIS | CYTOKINESIS | MOTOR | KINESIN EG5 | CELL-CYCLE | Phosphorylation - physiology | Cell Cycle - genetics | Humans | Centrosome - drug effects | Mitosis - genetics | Gene Knockdown Techniques | Cell Cycle Proteins - antagonists & inhibitors | Phosphorylation - genetics | Transfection | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Kinesin - genetics | Centrosome - physiology | Phosphorylation - drug effects | Kinesin - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - physiology | RNA, Small Interfering - pharmacology | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Enzyme Activation - drug effects | Centrosome - metabolism | Kinesin - metabolism | Mitosis - drug effects | Mitosis - physiology | Signal Transduction - drug effects | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Kinesin - physiology | HeLa Cells | Cell Cycle - drug effects | Enzyme Activation - genetics | Cell Cycle Proteins - physiology | Enzyme Activation - physiology | NIMA-Related Kinases | Cell division | Signal transduction | Kinases | Gene expression | Molecular biology | Ribonucleic acid--RNA
Journal Article