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1. Full Text hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids
by Xiang, Yangfei and Tanaka, Yoshiaki and Cakir, Bilal and Patterson, Benjamin and Kim, Kun-Yong and Sun, Pingnan and Kang, Young-Jin and Zhong, Mei and Liu, Xinran and Patra, Prabir and Lee, Sang-Hun and Weissman, Sherman M and Park, In-Hyun
Cell stem cell, ISSN 1934-5909, 03/2019, Volume 24, Issue 3, pp. 487 - 497.e7
fusion | cortex | single cell RNA-seq | brain organoid | thalamic organoid | thalamocortical | hESC | corticothalamic | thalamus | Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Models, Biological | Human Embryonic Stem Cells - cytology | Humans | Organoids - metabolism | Organoids - cytology | Thalamus - cytology | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Index Medicus
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2. Full Text Cell diversity and network dynamics in photosensitive human brain organoids
by Quadrato, Giorgia and Nguyen, Tuan and Macosko, Evan Z and Sherwood, John L and Yang, Sung Min and Berger, Daniel R and Maria, Natalie and Scholvin, Jorg and Goldman, Melissa and Kinney, Justin P and Boyden, Edward S and Lichtman, Jeff W and Williams, Ziv M and McCarroll, Steven A and Arlotta, Paola
Nature (London), ISSN 0028-0836, 05/2017, Volume 545, Issue 7652, pp. 48 - 53
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Retina - metabolism | Humans | Transcriptome | Gene Expression Profiling | Cerebral Cortex - cytology | Neural Pathways - physiology | Neurogenesis | Cerebral Cortex - metabolism | Nerve Net - cytology | Retina - cytology | Time Factors | Light | Neural Pathways - radiation effects | Dendrites | Nerve Net - radiation effects | Single-Cell Analysis | Organoids - radiation effects | Cell Line | Brain - cytology | Pluripotent Stem Cells - cytology | Cell Separation | Organoids - cytology | Photoreceptor Cells, Vertebrate - cytology | Organ Specificity | Sequence Analysis, RNA | Organoids - growth & development | Neural Pathways - cytology | In Vitro Techniques | Brain cells | Physiological aspects | Brain research | Research | Biological diversity | Brain | Photosensitivity | Cerebral cortex | Neurons | Developmental biology | Circuits | Retina | Stimulation | Cortex (somatosensory) | Gene expression | Dendritic spines | Organoids | Neural networks | Stem cells | Three dimensional models | Active control | In vitro methods and tests | Sensory stimuli | Index Medicus
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3. Full Text Cerebral organoids model human brain development and microcephaly
by Lancaster, Madeline A and Renner, Magdalena and Martin, Carol-Anne and Wenzel, Daniel and Bicknell, Louise S and Hurles, Matthew E and Homfray, Tessa and Penninger, Josef M and Jackson, Andrew P and Knoblich, Juergen A
Nature (London), ISSN 0028-0836, 2013, Volume 501, Issue 7467, pp. 373 - 379
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Biological and medical sciences | Neurons - pathology | Brain - anatomy & histology | Humans | Cerebral Cortex - pathology | Neurons - cytology | Brain - growth & development | Neural Stem Cells - cytology | Cerebral Cortex - cytology | Neurogenesis | Microcephaly - pathology | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - pathology | Brain - cytology | Organoids - pathology | Organoids - cytology | Neural Stem Cells - pathology | Animals | Cerebral Cortex - embryology | Organoids - growth & development | Models, Biological | Brain - pathology | Cerebral Cortex - growth & development | Mice | Organoids - embryology | Tissue Culture Techniques - methods | Research | Brain diseases | Brain | Population | Kinases | Pathogenesis | Methods | Index Medicus
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4. Full Text Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output
by Giandomenico, Stefano L and Mierau, Susanna B and Gibbons, George M and Wenger, Lea M. D and Masullo, Laura and Sit, Timothy and Sutcliffe, Magdalena and Boulanger, Jerome and Tripodi, Marco and Derivery, Emmanuel and Paulsen, Ole and Lakatos, András and Lancaster, Madeline A
Nature neuroscience, ISSN 1097-6256, 04/2019, Volume 22, Issue 4, pp. 669 - 679
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell Survival | Humans | Pluripotent Stem Cells - physiology | Organoids - cytology | Male | Neurons - cytology | Axons - physiology | Cerebral Cortex - cytology | Neural Pathways - physiology | Organoids - growth & development | Neural Pathways - cytology | Neurons - physiology | Cerebral Cortex - growth & development | Female | Tissue Culture Techniques - methods | RNA sequencing | Nervous system diseases | Research | Neurons | Neurophysiology | Explants | Cell culture | Brain | Spinal cord | Cell survival | Muscles | Ribonucleic acid--RNA | Neurodevelopmental disorders | Gene sequencing | Neurological diseases | Organoids | Neural networks | Morphology | Index Medicus | cerebral organoids | nerve tracts | corticospinal tract | in vitro | corpus callosum | Axon guidance | brain and spinal cord injury | organoid
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5. Full Text Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration
by Xiang, Yangfei and Tanaka, Yoshiaki and Patterson, Benjamin and Kang, Young-Jin and Govindaiah, Gubbi and Roselaar, Naomi and Cakir, Bilal and Kim, Kun-Yong and Lombroso, Adam P and Hwang, Sung-Min and Zhong, Mei and Stanley, Edouard G and Elefanty, Andrew G and Naegele, Janice R and Lee, Sang-Hun and Weissman, Sherman M and Park, In-Hyun
Cell stem cell, ISSN 1934-5909, 09/2017, Volume 21, Issue 3, pp. 383 - 398.e7
cortex | fusion | single cell RNA-seq | brain organoid | transcriptional regulation | neuronal migration | interneuron | MGE | hESC | ATAC-seq | Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Chromatin - metabolism | Brain - cytology | Brain - embryology | Pluripotent Stem Cells - cytology | Humans | Organoids - cytology | Transcriptome - genetics | Cerebral Cortex - cytology | Pluripotent Stem Cells - metabolism | Cell Lineage | Interneurons - metabolism | Sequence Analysis, RNA | Models, Biological | Cell Differentiation | Interneurons - cytology | Median Eminence - cytology | Cell Movement | Index Medicus
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6. Full Text Modeling Patient-Derived Glioblastoma with Cerebral Organoids
by Linkous, Amanda and Balamatsias, Demosthenes and Snuderl, Matija and Edwards, Lincoln and Miyaguchi, Ken and Milner, Teresa and Reich, Batsheva and Cohen-Gould, Leona and Storaska, Andrew and Nakayama, Yasumi and Schenkein, Emily and Singhania, Richa and Cirigliano, Stefano and Magdeldin, Tarig and Lin, Ying and Nanjangud, Gouri and Chadalavada, Kalyani and Pisapia, David and Liston, Conor and Fine, Howard A
Cell reports (Cambridge), ISSN 2211-1247, 03/2019, Volume 26, Issue 12, pp. 3203 - 3211.e5
cerebral organoids | tissue engineering | glioblastoma | brain tumors | stem-cell-based disease models | glioma | tumor microtubes | cancer stem cells | glioma stem cells | human embryonic stem cells | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Organoids - pathology | Neoplastic Stem Cells - metabolism | Models, Biological | Neoplasm Invasiveness | Glioblastoma - pathology | Humans | Organoids - metabolism | Brain Neoplasms - pathology | Neoplastic Stem Cells - pathology | Glioblastoma - metabolism | Brain Neoplasms - metabolism | Index Medicus
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7. Full Text Glioblastoma Model Using Human Cerebral Organoids
by Ogawa, Junko and Pao, Gerald M and Shokhirev, Maxim N and Verma, Inder M
Cell reports (Cambridge), ISSN 2211-1247, 04/2018, Volume 23, Issue 4, pp. 1220 - 1229
glioma | glioblastoma | CRISPR/Cas9 | cerebral organoid | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasm Transplantation | Organoids - pathology | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Mice, SCID | Brain Neoplasms - metabolism | Mice, Knockout | Animals | Heterografts | Glioblastoma - genetics | Models, Biological | Glioblastoma - pathology | Organoids - metabolism | Cell Line, Tumor | Glioblastoma - metabolism | Mice, Inbred NOD | Mice | Index Medicus
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8. Full Text Fused cerebral organoids model interactions between brain regions
by Bagley, Joshua A and Reumann, Daniel and Bian, Shan and Lévi-Strauss, Julie and Knoblich, Juergen A
Nature methods, ISSN 1548-7091, 06/2017, Volume 14, Issue 7, pp. 743 - 751
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Organoids - physiology | Interneurons - physiology | Brain - embryology | Animals | Humans | Cell Communication | Cerebral Cortex - physiology | Cell Culture Techniques | Cerebral Cortex - cytology | Cell Movement | Brain | Neural circuitry | Brain research | Localization of functions | Cerebrum | Models | Observations | Neuroimaging | Leukocyte migration | Regional analysis | Forebrain | Fluorescence | Pharmacology | Chemical compounds | Patients | CXCR4 protein | Defects | γ-Aminobutyric acid | Organoids | Fusion | In vitro methods and tests | Cell migration | Index Medicus
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9. Full Text Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution
by Pollen, Alex A and Bhaduri, Aparna and Andrews, Madeline G and Nowakowski, Tomasz J and Meyerson, Olivia S and Mostajo-Radji, Mohammed A and Di Lullo, Elizabeth and Alvarado, Beatriz and Bedolli, Melanie and Dougherty, Max L and Fiddes, Ian T and Kronenberg, Zev N and Shuga, Joe and Leyrat, Anne A and West, Jay A and Bershteyn, Marina and Lowe, Craig B and Pavlovic, Bryan J and Salama, Sofie R and Haussler, David and Eichler, Evan E and Kriegstein, Arnold R
Cell (Cambridge), ISSN 0092-8674, 02/2019, Volume 176, Issue 4, pp. 743 - 756.e17
single-cell RNA sequencing | cerebral organoids | macaque | radial glia | human-specific evolution | mTOR | chimpanzee | cortical development | neural progenitor cells | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Brain - cytology | Gene Regulatory Networks - genetics | Pluripotent Stem Cells - cytology | Species Specificity | Humans | Pan troglodytes | Transcriptome - genetics | Cell Culture Techniques - methods | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Biological Evolution | Neurogenesis - genetics | Cell Differentiation - genetics | Animals | Organoids - growth & development | Organoids - metabolism | Macaca | Induced Pluripotent Stem Cells - cytology | Single-Cell Analysis | RNA sequencing | Medical colleges | Brain | RNA | Developmental biology | Genes | Genomics | Stress (Physiology) | Gene expression | Stem cell research | Anopheles | Brain research | Evolutionary biology | Analysis | Stem cells | Primates | Human evolution | Models | Index Medicus
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