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Brain, behavior, and immunity, ISSN 0889-1591, 2013, Volume 33, Issue Jul.,31, pp. 183 - 189
Highlight • High levels of inflammatory markers in cerebrospinal fluid were associated with fatigue, depression, and cognitive impairment in patients with... 
Psychiatry | Allergy and Immunology | C-reactive protein | Cytokines | Neuroinflammation | Depression | Fatigue | Cerebrospinal fluid | Parkinson’s disease | Dementia | Parkinson's disease | TREATMENT-RESISTANT DEPRESSION | ALZHEIMERS-DISEASE | MAJOR DEPRESSION | IMMUNOLOGY | FACTOR ANTAGONIST INFLIXIMAB | NEUROSCIENCES | NONMOTOR SYMPTOMS | TNF-ALPHA | DIAGNOSTIC-CRITERIA | BRAIN | Humans | Middle Aged | Fatigue - complications | Dementia - diagnosis | Male | Chemokine CCL26 | Chemokines, CC - cerebrospinal fluid | Chemokine CCL2 - cerebrospinal fluid | Inflammation Mediators - cerebrospinal fluid | Depression - cerebrospinal fluid | Parkinson Disease - cerebrospinal fluid | Dementia - cerebrospinal fluid | Depression - complications | Female | Interleukin-6 - cerebrospinal fluid | Cognition Disorders - cerebrospinal fluid | Parkinson Disease - complications | Chemokine CCL11 - cerebrospinal fluid | Chemokine CCL3 - cerebrospinal fluid | Tumor Necrosis Factor-alpha - cerebrospinal fluid | C-Reactive Protein - cerebrospinal fluid | Chemokine CCL4 - cerebrospinal fluid | Cognition Disorders - complications | Dementia - complications | Fatigue - cerebrospinal fluid | Parkinson Disease - diagnosis | Aged | Chemokine CCL24 - cerebrospinal fluid | Depression, Mental | Diagnosis | Neurologi | Clinical Medicine | Neurology | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Arthritis research & therapy, ISSN 1478-6354, 2004, Volume 6, Issue 6, pp. R551 - 556
Symptoms originating from the central nervous system (CNS) occur frequently in patients with systemic lupus erythematosus (SLE), and CNS involvement in lupus... 
matrix metalloproteinase-2 | PROTEIN | matrix metalloproteinase-9 | CEREBROSPINAL-FLUID INTERLEUKIN-6 | INVOLVEMENT | neuropsychiatric involvement in systemic lupus erythematosus | NECROSIS-FACTOR-ALPHA | RHEUMATOLOGY | MENINGITIS | MULTIPLE-SCLEROSIS | cerebrospinal fluid | NEUROPSYCHIATRIC LUPUS | magnetic resonance imaging of the brain | MATRIX-METALLOPROTEINASE-9 | EXPRESSION | BLOOD | Central Nervous System Diseases - pathology | Lupus Erythematosus, Systemic - complications | Humans | Meningitis, Aseptic - etiology | Middle Aged | Brain - enzymology | Interleukin-8 - cerebrospinal fluid | Male | Psychotic Disorders - cerebrospinal fluid | Myelitis, Transverse - enzymology | tau Proteins | Myelitis, Transverse - cerebrospinal fluid | Glial Fibrillary Acidic Protein - cerebrospinal fluid | Aged, 80 and over | Adult | Female | Interleukin-6 - cerebrospinal fluid | Psychotic Disorders - enzymology | Cerebrospinal Fluid Proteins - analysis | Lupus Erythematosus, Systemic - enzymology | Myelitis, Transverse - etiology | Seizures - enzymology | Central Nervous System Diseases - enzymology | Central Nervous System Diseases - cerebrospinal fluid | Matrix Metalloproteinase 2 - cerebrospinal fluid | Nerve Tissue Proteins - cerebrospinal fluid | Enzyme Induction | Lupus Erythematosus, Systemic - cerebrospinal fluid | Meningitis, Aseptic - cerebrospinal fluid | Leukocytosis - etiology | Magnetic Resonance Imaging | Central Nervous System Diseases - etiology | Adolescent | Seizures - etiology | Brain - pathology | Seizures - cerebrospinal fluid | Aged | Matrix Metalloproteinase 9 - cerebrospinal fluid | Lupus Erythematosus, Systemic - pathology | Meningitis, Aseptic - enzymology | Psychotic Disorders - etiology | Myelitis | Brain/enzymology/pathology | Cerebrospinal Fluid Proteins/analysis | Interleukin-6/cerebrospinal fluid | Transverse/cerebrospinal fluid/enzymology/etiology | MEDICIN OCH HÄLSOVETENSKAP | Glial Fibrillary Acidic Protein/cerebrospinal fluid | Seizures/cerebrospinal fluid/enzymology/etiology | 80 and over | Psychotic Disorders/cerebrospinal fluid/enzymology/etiology | Aseptic/cerebrospinal fluid/enzymology/etiology | Lupus Erythematosus | Meningitis | fluid/enzymology/etiology/pathology | MEDICAL AND HEALTH SCIENCES | fluid/complications/enzymology/pathology | Leukocytosis/etiology | Nerve Tissue Proteins/cerebrospinal fluid | Matrix Metalloproteinase 9/cerebrospinal fluid | Interleukin-8/cerebrospinal fluid | Central Nervous System Diseases/cerebrospinal | Matrix Metalloproteinase 2/cerebrospinal fluid | Systemic/cerebrospinal
Journal Article
Annals of neurology, ISSN 0364-5134, 2011, Volume 69, Issue 3, pp. 570 - 580
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 11/2015, Volume 14, Issue 11, pp. 4486 - 4501
Analysis of the cerebrospinal fluid (CSF) proteome has proven valuable to the study of neurodegenerative disorders. To identify new protein/pathway alterations... 
LC-MS/MS | proteomics | cerebrospinal fluid | liquid chromatography-tandem mass spectrometry | mass spectrometry | biomarker | amyotrophic lateral sclerosis | extracellular matrix | MOTOR-NEURONS | ANTERIOR HORN NEURONS | PROTEIN | BIOCHEMICAL RESEARCH METHODS | ALS | CSF BIOMARKERS | FRONTOTEMPORAL LOBAR DEGENERATION | SEMAPHORIN 3A | GENE ONTOLOGY | DISCOVERY | MOUSE MODEL | Proteome - genetics | Humans | Middle Aged | Immunoglobulins - cerebrospinal fluid | Amyotrophic Lateral Sclerosis - diagnosis | Synapses - genetics | Cerebrospinal Fluid Proteins - genetics | Immunoglobulins - genetics | Support Vector Machine | Alzheimer Disease - pathology | Adaptor Proteins, Signal Transducing - cerebrospinal fluid | Motor Neuron Disease - genetics | Cell Adhesion Molecules - isolation & purification | Extracellular Matrix Proteins - isolation & purification | Proteomics - methods | Tandem Mass Spectrometry - methods | Amyotrophic Lateral Sclerosis - genetics | Extracellular Matrix Proteins - genetics | Motor Neuron Disease - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Motor Neuron Disease - pathology | Amyotrophic Lateral Sclerosis - pathology | Calcium-Binding Proteins - isolation & purification | Biomarkers - cerebrospinal fluid | Calcium-Binding Proteins - cerebrospinal fluid | Proteome - metabolism | Calcium-Binding Proteins - genetics | Cell Adhesion Molecules - genetics | Adaptor Proteins, Signal Transducing - isolation & purification | Cerebrospinal Fluid Proteins - isolation & purification | Case-Control Studies | Extracellular Matrix - chemistry | Synaptic Transmission | Alzheimer Disease - diagnosis | Immunoglobulins - isolation & purification | Synapses - metabolism | Amyloid beta-Protein Precursor - cerebrospinal fluid | Amyotrophic Lateral Sclerosis - cerebrospinal fluid | Sensitivity and Specificity | Adult | Cerebrospinal Fluid Proteins - cerebrospinal fluid | Proteome - isolation & purification | Diagnosis, Differential | Cell Adhesion Molecules - cerebrospinal fluid | Inflammation | Amyloid beta-Protein Precursor - isolation & purification | Amyloid beta-Protein Precursor - genetics | Extracellular Matrix Proteins - cerebrospinal fluid | Adaptor Proteins, Signal Transducing - genetics | Alzheimer Disease - genetics | Chromatography, Liquid - methods | Motor Neuron Disease - diagnosis | LC-MS
Journal Article
Neuromolecular medicine, ISSN 1559-1174, 2013, Volume 16, Issue 1, pp. 150 - 160
The success of future intervention strategies for Alzheimer’s disease (AD) will likely rely on the development of treatments starting early in the disease... 
Neurology | Neurosciences | Biomedicine | TFEB | Cathepsins | Internal Medicine | DRAM | hsc70 | PICALM | Proteasome | STANDARDIZATION | DEMENTIA | HUMAN CEREBROSPINAL-FLUID | AUTOPHAGY | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | PLASMA | DOWN-SYNDROME | UBIQUITIN PROTEASOME SYSTEM | EARLY ENDOSOMES | Lysosomal-Associated Membrane Protein 2 - cerebrospinal fluid | Phagosomes - chemistry | Lysosomes - chemistry | Lysosome-Associated Membrane Glycoproteins - cerebrospinal fluid | Humans | Middle Aged | Male | Microtubule-Associated Proteins - cerebrospinal fluid | Autophagy | rab GTP-Binding Proteins - cerebrospinal fluid | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Adult | Albumins - cerebrospinal fluid | Female | Cerebrospinal Fluid Proteins - cerebrospinal fluid | Peptide Fragments - cerebrospinal fluid | Nerve Tissue Proteins - cerebrospinal fluid | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Vesicular Transport Proteins - cerebrospinal fluid | rab3 GTP-Binding Proteins - cerebrospinal fluid | Endosomes - chemistry | Aged | Biomarkers - cerebrospinal fluid | Resveratrol | Amyloid beta-protein | Physiological aspects | Heat shock proteins | Brain damage | Development and progression | Biological markers | Alzheimer's disease | Membrane proteins | Original Paper
Journal Article
Translational psychiatry, ISSN 2158-3188, 2017, Volume 7, Issue 1, pp. e995 - e995
Brain autopsy and biomarker studies indicate that the pathology of Alzheimer's disease (AD) is initiated at least 10-20 years before clinical symptoms. This... 
ENTORHINAL CORTEX | VASCULAR DEMENTIA | PSYCHIATRY | ALZHEIMERS-DISEASE | NONDEMENTED INDIVIDUALS | ACID-BINDING PROTEIN | A-BETA | APOE EPSILON-4 ALLELE | MILD COGNITIVE IMPAIRMENT | DIAGNOSTIC-CRITERIA | CEREBROSPINAL-FLUID LEVELS | Myelin Basic Protein - cerebrospinal fluid | Orexins - cerebrospinal fluid | Apolipoprotein E4 - genetics | Humans | Vascular Endothelial Growth Factor A - cerebrospinal fluid | Fatty Acid Binding Protein 3 - cerebrospinal fluid | Male | Healthy Volunteers | Chitinase-3-Like Protein 1 - cerebrospinal fluid | Neurofilament Proteins - cerebrospinal fluid | Sweden | Aged, 80 and over | Amyloid beta-Peptides - cerebrospinal fluid | Female | Neurogranin - cerebrospinal fluid | Peptide Fragments - cerebrospinal fluid | Cross-Sectional Studies | tau Proteins - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Phosphoproteins - cerebrospinal fluid | Brain-Derived Neurotrophic Factor - cerebrospinal fluid | Aged | Neurocalcin - cerebrospinal fluid | Biomarkers - cerebrospinal fluid | Alzheimer Disease - genetics | Original | cerebrospinal-fluid levels | vascular dementia | zeitschrift fur gerontologie | acid-binding | apolipoprotein-e | journal of psychiatric research | p163 | nondemented individuals | een b | apoe epsilon-4 allele | lstein mf | 1975 | p189 | a-beta | 1993 | diagnostic-criteria | v12 | protein | Psykiatri | mild cognitive impairment | v26 | Psychiatry | alzheimers-disease
Journal Article
Neurology, ISSN 1526-632X, 2018, Volume 91, Issue 9, pp. e867 - e877
Journal Article
British journal of cancer, ISSN 1532-1827, 2015, Volume 114, Issue 2, pp. 151 - 162
textabstractBackground:The current biomarkers alpha-fetoprotein and human chorionic gonadotropin have limited sensitivity and specificity for diagnosing... 
CIRCULATING MICRORNAS | PROFILES | germ-cell tumour | relapse | QUANTIFICATION | MIR-302 CLUSTERS | TESTICULAR CANCER | diagnosis | biomarker | IDENTIFICATION | blood | paediatric | REAL-TIME PCR | BIOMARKERS | ONCOLOGY | MIR-371-SIMILAR-TO-373 | MIRNA | microRNA | serum | Central Nervous System Neoplasms - blood | Germinoma - blood | Germinoma - diagnosis | Germinoma - cerebrospinal fluid | Testicular Neoplasms - cerebrospinal fluid | Humans | Child, Preschool | Infant | Male | Neoplasms, Germ Cell and Embryonal - blood | Neoplasms, Germ Cell and Embryonal - diagnosis | Sacrococcygeal Region | Endodermal Sinus Tumor - diagnosis | Ovarian Neoplasms - cerebrospinal fluid | Carcinoma, Embryonal - cerebrospinal fluid | Choriocarcinoma, Non-gestational - diagnosis | Endodermal Sinus Tumor - blood | Neoplasm Recurrence, Local - cerebrospinal fluid | Sensitivity and Specificity | Chorionic Gonadotropin - blood | Chorionic Gonadotropin - cerebrospinal fluid | Polymerase Chain Reaction | Female | Choriocarcinoma, Non-gestational - cerebrospinal fluid | Child | Neoplasm Recurrence, Local - blood | Infant, Newborn | alpha-Fetoproteins - metabolism | Testicular Neoplasms - diagnosis | Carcinoma, Embryonal - blood | MicroRNAs - cerebrospinal fluid | Choriocarcinoma, Non-gestational - blood | Ovarian Neoplasms - diagnosis | alpha-Fetoproteins - cerebrospinal fluid | Ovarian Neoplasms - blood | Neoplasm Recurrence, Local - diagnosis | Biomarkers, Tumor - blood | Endodermal Sinus Tumor - cerebrospinal fluid | Carcinoma, Embryonal - diagnosis | Adolescent | Biomarkers, Tumor - cerebrospinal fluid | MicroRNAs - blood | Testicular Neoplasms - blood | Central Nervous System Neoplasms - diagnosis | Central Nervous System Neoplasms - cerebrospinal fluid | Neoplasms, Germ Cell and Embryonal - cerebrospinal fluid | Clinical Study
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2006, Volume 21, Issue 5, pp. 668 - 676
Abstract Complex Regional Pain Syndrome is a severe chronic pain condition characterized by sensory, autonomic, motor and dystrophic signs and symptoms. The... 
Psychiatry | Allergy and Immunology | MCP1 | Cytokines | Calcium | Nitric oxide | Cerebrospinal fluid | Glutamate | CRPS | Chemokines | GFAP | DISEASE PATIENTS | nitric oxide | calcium | SPINAL MICROGLIA | AMYOTROPHIC-LATERAL-SCLEROSIS | IMMUNOLOGY | chemokines | PATHOLOGICAL PAIN | NEUROSCIENCES | CEREBROSPINAL-FLUID LEVELS | NEUROPATHIC PAIN | MULTIPLE-SCLEROSIS | FIBRILLARY ACIDIC PROTEIN | cerebrospinal fluid | cytokines | CENTRAL-NERVOUS-SYSTEM | NITRIC-OXIDE NO | glutamate | Humans | Middle Aged | Nitrites - cerebrospinal fluid | Male | Hydrocephalus - metabolism | Glucose - cerebrospinal fluid | Calcium - cerebrospinal fluid | Glial Fibrillary Acidic Protein - cerebrospinal fluid | Amyotrophic Lateral Sclerosis - cerebrospinal fluid | Female | Radiculopathy - metabolism | Complex Regional Pain Syndromes - metabolism | Glutamic Acid - cerebrospinal fluid | Peripheral Nervous System Diseases - immunology | Spondylolisthesis - immunology | Chemokines - immunology | Cytokines - immunology | Amyotrophic Lateral Sclerosis - immunology | Complex Regional Pain Syndromes - cerebrospinal fluid | Spondylolisthesis - metabolism | Chemokines - cerebrospinal fluid | Spondylolisthesis - cerebrospinal fluid | Radiculopathy - cerebrospinal fluid | Peripheral Nervous System Diseases - cerebrospinal fluid | Cytokines - cerebrospinal fluid | Peripheral Nervous System Diseases - metabolism | Hydrocephalus - immunology | Nitrates - cerebrospinal fluid | Amyotrophic Lateral Sclerosis - metabolism | Complex Regional Pain Syndromes - immunology | Neuroglia - metabolism | Aged | Biomarkers - cerebrospinal fluid | Hydrocephalus - cerebrospinal fluid | Nitric Oxide - metabolism | Radiculopathy - immunology | Cerebrospinal fluid proteins
Journal Article
Alzheimer's research & therapy, ISSN 1758-9193, 2017, Volume 9, Issue 1, pp. 43 - 11
Journal Article