X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
ces1 (48) 48
index medicus (39) 39
pharmacology & pharmacy (36) 36
humans (30) 30
clopidogrel (20) 20
male (18) 18
metabolism (18) 18
female (17) 17
carboxylic ester hydrolases - genetics (15) 15
activation (14) 14
pharmacogenetics (14) 14
carboxylesterase 1 (13) 13
carboxylesterase (11) 11
carboxylic ester hydrolases - metabolism (11) 11
adult (10) 10
genotype (10) 10
middle aged (10) 10
pharmacology (10) 10
article (9) 9
biochemistry & molecular biology (9) 9
genetic aspects (9) 9
hydrolysis (9) 9
analysis (8) 8
ces2 (8) 8
cyp2c19 (8) 8
genes (8) 8
polymorphism (8) 8
young adult (8) 8
carboxylesterase - metabolism (7) 7
enzymes (7) 7
expression (7) 7
human carboxylesterase 1 (7) 7
human liver (7) 7
mammalian carboxylesterases (7) 7
oseltamivir (7) 7
pharmacokinetics (7) 7
polymorphism, single nucleotide (7) 7
aged (6) 6
catalytic-properties (6) 6
gene (6) 6
genetic research (6) 6
physiological aspects (6) 6
aspirin (5) 5
gene expression (5) 5
liver (5) 5
methylphenidate (5) 5
research (5) 5
ticlopidine - analogs & derivatives (5) 5
toxicology (5) 5
association (4) 4
biotransformation (4) 4
carboxylesterase - genetics (4) 4
carboxylesterases (4) 4
carboxylic ester hydrolases - antagonists & inhibitors (4) 4
cardiovascular diseases (4) 4
coronary-artery-disease (4) 4
cyp2c19 genotype (4) 4
dabigatran (4) 4
drug metabolism (4) 4
drugs (4) 4
esters (4) 4
gene frequency (4) 4
genetic polymorphisms (4) 4
genetics (4) 4
genotyping (4) 4
hep g2 cells (4) 4
liver - metabolism (4) 4
multidisciplinary sciences (4) 4
polymerase chain reaction (4) 4
prodrug oseltamivir (4) 4
profile (4) 4
risk (4) 4
substrates (4) 4
therapeutics. pharmacology (4) 4
variants (4) 4
abcb1 (3) 3
acute coronary syndrome (3) 3
adhd (3) 3
adolescent (3) 3
aged, 80 and over (3) 3
alleles (3) 3
asian continental ancestry group - genetics (3) 3
bioavailability (3) 3
biomedicine (3) 3
biotechnology & applied microbiology (3) 3
chemical compounds (3) 3
chemistry, multidisciplinary (3) 3
diabetes (3) 3
diseases of the circulatory system (3) 3
drug therapy (3) 3
drug-metabolism (3) 3
enalapril (3) 3
genetic variation (3) 3
genetics & heredity (3) 3
identification (3) 3
in-vitro evaluation (3) 3
inhibition (3) 3
inhibitors (3) 3
insulin-resistance (3) 3
irinotecan (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Science, ISSN 0036-8075, 4/2010, Volume 328, Issue 5978, pp. 636 - 639
Journal Article
Pharmacogenetics and Genomics, ISSN 1744-6872, 01/2013, Volume 23, Issue 1, pp. 1 - 8
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 16364 - 11
Human carboxylesterases has been proven to be age and race-related and a sound basis of clinical medication. PLE involve in signal transduction and highly... 
ACTIVATION | PHARMACOKINETICS | ANTIINFLUENZA PRODRUG OSELTAMIVIR | CLONING | FUNCTIONAL EXPRESSION | MULTIDISCIPLINARY SCIENCES | HYDROLYSIS | MAMMALIAN CARBOXYLESTERASES | HEPATIC STEATOSIS | ISOENZYMES | CES1 | Signal transduction | Hogs | Esterase | Isoenzymes | Liver | mRNA | Transduction | Age | Age groups | Age differences
Journal Article
TERAPEVTICHESKII ARKHIV, ISSN 0040-3660, 2019, Volume 91, Issue 8, pp. 22 - 27
Aim. To evaluate the clinical and economic feasibility of pharmacogenetic testing (PGT) for dabigataran etexilate administration in the treatment of atrial... 
MEDICINE, GENERAL & INTERNAL | COST-EFFECTIVENESS | THERAPY | WARFARIN | dabigatran | RISK | pharmacoeconomics | pharmacogenetic testing | CES1
Journal Article
Journal Article
MOLECULES, ISSN 1420-3049, 08/2019, Volume 24, Issue 15, p. 2747
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 09/2018, Volume 8, Issue 5, pp. 699 - 712
Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2)... 
Inducer | Inhibitor spectra | CES2 | Substrate preference | CES1 | Human carboxylesterases | 2-PHOTON FLUORESCENT-PROBE | NATURAL-PRODUCTS | CRYSTAL-STRUCTURE | HUMAN LIVER COCAINE | SUBSTRATE-SPECIFICITY | IN-VITRO EVALUATION | CATALYTIC-PROPERTIES | SELECTIVE INHIBITORS | MAMMALIAN CARBOXYLESTERASES | PHARMACOLOGY & PHARMACY | HUMAN INTESTINAL CARBOXYLESTERASE | Review
Journal Article
Journal Article