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PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9
The intracellular second messenger cyclic AMP (cAMP) is degraded by phosphodiesterases (PDE). The knowledge of individual families and subtypes of PDEs is... 
ACTIVATION | ISOFORMS | PURIFICATION | BIOLOGY | CGMP | DYNAMICS | GENE FAMILY | RECEPTOR | CILOSTAMIDE | NUCLEOTIDE PHOSPHODIESTERASE | CAMP
Journal Article
JAMA OPHTHALMOLOGY, ISSN 2168-6165, 06/2019, Volume 137, Issue 6, pp. 679 - 680
In this issue of JAMA Ophthalmology, Khateb et al1 fill a key knowledge gap by providing a comprehensive retrospective analysis of retinitis pigmentosa (RP)... 
CGMP | OPHTHALMOLOGY | BETA-SUBUNIT | Retinitis pigmentosa | Retina | Retinitis | Ophthalmology | Nyctalopia | Acuity | Phosphodiesterase | Index Medicus | Abridged Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2010, Volume 30, Issue 10, pp. 1998 - 2004
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2006, Volume 38, Issue 7, pp. 794 - 800
Journal Article
Oncogene, ISSN 0950-9232, 03/2015, Volume 34, Issue 12, pp. 1499 - 1509
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2009, Volume 29, Issue 25, pp. 8075 - 8086
Memory loss, synaptic dysfunction, and accumulation of amyloid beta-peptides (A beta) are major hallmarks of Alzheimer's disease (AD). Downregulation of the... 
NEURONAL GENES | SILDENAFIL | AVOIDANCE | SELECTIVE PDE5 INHIBITOR | NITRIC-OXIDE | CGMP | RAT HIPPOCAMPUS | MICE | MECHANISMS | DYSFUNCTION | NEUROSCIENCES | Immunohistochemistry | Memory - drug effects | Piperazines - administration & dosage | Phosphodiesterase 5 Inhibitors | Purines - administration & dosage | Sulfones - pharmacology | Sildenafil Citrate | Time Factors | Amyloid beta-Peptides - metabolism | Polymerase Chain Reaction | Spatial Behavior - drug effects | Synaptic Transmission - drug effects | Phosphorylation - drug effects | Piperazines - pharmacokinetics | Alzheimer Disease - psychology | Disease Models, Animal | Psychomotor Performance | Conditioning, Classical - drug effects | Phosphodiesterase Inhibitors - pharmacokinetics | Purines - pharmacology | Purines - pharmacokinetics | Injections, Intraperitoneal | Alzheimer Disease - drug therapy | Phosphodiesterase Inhibitors - pharmacology | Mice, Transgenic | Treatment Outcome | Sulfones - pharmacokinetics | Piperazines - pharmacology | Neuropsychological Tests | Phosphodiesterase Inhibitors - administration & dosage | Amyloid beta-Protein Precursor - genetics | Animals | Analysis of Variance | Cyclic GMP - metabolism | Alzheimer Disease - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Mice | Mutation | Sulfones - administration & dosage | Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2013, Volume 23, Issue 11, pp. 3438 - 3442
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 04/2018, Volume 365, Issue 1, pp. 179 - 188
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 11/2009, Volume 105, Issue 10, pp. 956 - 964
Journal Article