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European Journal of Pharmacology, ISSN 0014-2999, 12/2019, Volume 864, p. 172726
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2006, Volume 530, Issue 1, pp. 107 - 116
This study sets out to characterise calcitonin gene-related peptide (CGRP) receptors in human and porcine isolated proximal and distal coronary arteries using... 
[Cys(Et) 2,7]-h-αCGRP | Human coronary artery | CGRP receptor | BIBN4096BS | [Cys(Acm) 2,7]-h-αCGRP | h-αCalcitonin gene-related peptide (h-αCGRP) | h-αCGRP 8-37 | h-αCGRP | Cys(Acm) | Cys(Et) | h-alpha CGRP(8-37) | GENE-RELATED PEPTIDE | ANTAGONIST | VAS-DEFERENS | [Cys(Et)(2.7)]-h-alpha CGRP | PHARMACOLOGICAL CHARACTERIZATION | human coronary artery | [Cys(Acm)(2.7)]-h-alpha CGRP | ADRENOMEDULLIN | PROFILE | PHARMACOLOGY & PHARMACY | INDUCED RELAXATION | h-alpha calcitonin gene-related peptide (h-alpha CGRP) | EXPRESSION | BRAIN | Receptors, Calcitonin - metabolism | Calcitonin Gene-Related Peptide - analogs & derivatives | Humans | Middle Aged | Child, Preschool | Male | Receptors, Calcitonin - genetics | Substance P - pharmacology | Intracellular Signaling Peptides and Proteins - metabolism | Calcitonin Receptor-Like Protein | Coronary Vessels - metabolism | Endothelium, Vascular - physiology | Dose-Response Relationship, Drug | Time Factors | Swine | Potassium Chloride - pharmacology | Adult | Female | Membrane Proteins - metabolism | Child | Cyclic AMP - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Vasoconstrictor Agents - pharmacology | Coronary Vessels - drug effects | Calcitonin Gene-Related Peptide - pharmacology | Colforsin - pharmacology | Coronary Vessels - physiology | Membrane Proteins - genetics | Transcription Factor Brn-3A - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Piperazines - pharmacology | Protein Isoforms - physiology | Receptors, Calcitonin Gene-Related Peptide - physiology | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Animals | Carrier Proteins - metabolism | Transcription Factor Brn-3A - genetics | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Adolescent | Receptor Activity-Modifying Proteins | Receptors, Calcitonin Gene-Related Peptide - genetics | Aged | Vasodilation - drug effects | In Vitro Techniques | Quinazolines - pharmacology | Protein Isoforms - genetics | Peptide hormones | Analysis | Calcitonin | Arteries
Journal Article
Journal Article
The Journal of Headache and Pain, ISSN 1129-2369, 12/2017, Volume 18, Issue 1, pp. 1 - 7
Journal Article
The Journal of Headache and Pain, ISSN 1129-2369, 12/2017, Volume 18, Issue 1, pp. 1 - 9
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 04/1998, Volume 123, Issue 8, pp. 1645 - 1654
Effects of adrenomedullin and α‐calcitonin gene‐related peptide (CGRP) on the contractions and cytosolic Ca2+ concentrations ([Ca2+]i) of the rat aorta and... 
endothelium | calcium | CGRP (8–37) | Adrenomedullin | smooth muscle | cyclic AMP | α‐calcitonin gene‐related peptide (α‐CGRP): β‐CGRP | Cgrp (8-37) | α-calcitonin gene-related peptide (α-CGRP) | Calcium | Cyclic AMP | Smooth muscle | β-CGRP | Endothelium | CYCLIC-AMP FORMATION | adrenomedullin | HYPOTENSIVE PEPTIDE | beta-CGRP | VASORELAXANT RESPONSES | THORACIC AORTA | VASCULAR SMOOTH-MUSCLE | alpha-calcitonin gene-related peptide (alpha-CGRP) | CGRP (8-37) | ENDOTHELIAL-CELLS | MULTIPLE RECEPTORS | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | BINDING-SITES | Muscle, Smooth, Vascular - metabolism | Peptides - antagonists & inhibitors | Rats, Wistar | Calcium - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | Male | omega-N-Methylarginine - pharmacology | Coronary Vessels - metabolism | Swine | Calcitonin Gene-Related Peptide - antagonists & inhibitors | Aorta, Thoracic - drug effects | Cyclic AMP - metabolism | Muscle, Smooth, Vascular - drug effects | Coronary Vessels - drug effects | Vasodilator Agents - pharmacology | Calcitonin Gene-Related Peptide - pharmacology | Vasodilator Agents - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Aorta, Thoracic - metabolism | Rats | Peptides - pharmacology | Animals | Muscle Contraction - drug effects | In Vitro Techniques | α-calcitonin gene-related peptide (α-CGRP): β-CGRP | Papers
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 09/2018, Volume 59, Issue 36, pp. 3389 - 3391
Olcegepant is one of the most potent and selective small molecule CGRP antagonists for the treatment of migraine headaches. Herein, we describe a new and... 
Reductive amination | Isocyanate | CGRP | Migraine | Protecting groups | POTENT | CHEMISTRY, ORGANIC | CGRP RECEPTOR ANTAGONISTS | DERIVATIVES | DISCOVERY
Journal Article
Cephalalgia, ISSN 0333-1024, 10/2019, Volume 39, Issue 12, pp. 1535 - 1543
Background Calcitonin gene-related peptide (CGRP) released from trigeminal nerve fibres indicates trigeminal activation and has a key role in migraine... 
triptan | Episodic migraine | chronic migraine | CGRP | NSAID
Journal Article