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Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 04/2019, Volume 168, pp. 146 - 153
CGRP, known as the most potent vasodilator substance, plays an important role in hypertension initiation and development. TRPV1 and TRPA1 are critical in... 
Dual-targeting | Anti-hypertensive agents | Rutaecarpine-NO donor hybrids | CGRP | ACTIVATION | CHEMISTRY, MEDICINAL | GENE-RELATED PEPTIDE | EVODIA-RUTAECARPA | INVOLVEMENT | PROGRESS | NITRIC-OXIDE | RESISTANCE | HYPERTENSION | RECEPTORS | Hypertension | Antihypertensive drugs | Drug discovery | Vasodilators
Journal Article
Neuropeptides, ISSN 0143-4179, 2011, Volume 45, Issue 6, pp. 391 - 400
Abstract Vagal sensory afferents innervating airways and abdominal tissues express TRPV1 and TRPA1, two depolarizing calcium permeable ion channels playing a... 
Endocrinology & Metabolism | Advanced Basic Science | Calcitonin gene-related peptide | Acrolein | Capsaicin | Inflammation | Mustard oil | Neuropathy | Endocannabinoids | TRP channels | Anandamide | ION-CHANNEL TRPA1 | INDUCED CGRP RELEASE | AIRWAY INFLAMMATION | RECEPTOR EXPRESSION | DORSAL-ROOT GANGLION | MUSTARD OIL RESPONSES | NEUROSCIENCES | CALCIUM-CHANNELS | ENDOCRINOLOGY & METABOLISM | VAGAL AFFERENT NEURONS | PRIMARY SENSORY NEURONS | ISOLATED RAT SKIN | Cannabinoid Receptor Modulators - pharmacology | Mustard Plant | Rats, Wistar | Capsaicin - pharmacology | Humans | Vagus Nerve - drug effects | Male | Receptor, Cannabinoid, CB2 - genetics | Sensory System Agents - pharmacology | TRPV Cation Channels - metabolism | Transient Receptor Potential Channels - metabolism | Calcitonin Gene-Related Peptide - metabolism | TRPC Cation Channels - genetics | Plant Oils - pharmacology | Vagus Nerve - metabolism | Mice, Inbred C57BL | Axons - drug effects | Axons - metabolism | Rats | Neuropeptides - metabolism | Vagus Nerve - cytology | Arachidonic Acids - pharmacology | TRPV Cation Channels - genetics | Mice, Knockout | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Receptor, Cannabinoid, CB1 - genetics | Transient Receptor Potential Channels - genetics | TRPA1 Cation Channel | Polyunsaturated Alkamides - pharmacology | TRPC Cation Channels - metabolism | Mice | Peptides | Metabolites | Calcitonin
Journal Article
Cardiovascular Therapeutics, ISSN 1755-5914, 10/2017, Volume 35, Issue 5, pp. e12276 - n/a
Summary Background Remote ischemic preconditioning (RIPC) is a phenomenon whereby transient nonlethal ischemia and reperfusion episodes confer protection... 
Cardioprotection | Ischemia | Capsaicin | TRPV1 channels | CGRP | Remote preconditioning | TRPV | channels | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | GENE-RELATED PEPTIDE | POSTISCHEMIC RECOVERY | ISOLATED RAT HEARTS | MYOCARDIAL-ISCHEMIA | TRPV1 | ISCHEMIA-REPERFUSION INJURY | CORONARY-ARTERY OCCLUSION | PHARMACOLOGY & PHARMACY | CHANNELS | Cardiology
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 02/2018, Volume 17, Issue 2, pp. 3246 - 3254
Periodontal diseases comprise mixed bacterial infections mainly caused by Gram-negative anaerobic bacteria. Lipopolysaccharides (LPS) are important virulence... 
Calcitonin gene-related peptide | Osteoblasts | Lipopolysaccharides | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | lipopolysaccharides | calcitonin gene-related peptide | IN-VITRO | BONE LOSS | ONCOLOGY | PERIODONTITIS | IMMUNE-RESPONSES | osteoblasts | DIFFERENTIATION | LIPOPOLYSACCHARIDE LPS | MAPK PATHWAY | CGRP | EXPRESSION
Journal Article
Journal Article
MEDIATORS OF INFLAMMATION, ISSN 0962-9351, 2017, Volume 2017, p. 9547056
Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used to treat migraine, but the mechanisms of their effects in this pathology are not fully... 
SYSTEM | NIMESULIDE | KETOPROFEN | INFLAMMATION | NEURONS | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | SUBSTANCE-P | ETORICOXIB | MIGRAINE | CGRP | CELL BIOLOGY
Journal Article