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Journal Article
Mini reviews in medicinal chemistry, ISSN 1389-5575, 11/2012, Volume 12, Issue 13, pp. 1394 - 1403
.... Chalcone based derivatives have gained heed since they own simple structures, and diverse pharmacological actions... 
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Chalcone - chemistry | Chalcone - pharmacology | Humans | Catalysis | Chalcone - chemical synthesis | Microwaves | Chemistry Techniques, Synthetic - methods
Journal Article
Anti-cancer agents in medicinal chemistry, 2018, Volume 18, Issue 7, pp. 1044 - 1053
... toxicity.OBJECTIVEIn this paper, a series of novel chalcone derivatives bearing diverse heterocycles have been synthesized and evaluated for their antiproliferative activity against A549... 
derivatives | apoptotic pathway | heterocycles | antiproliferative activity | Chalcone | cytotoxicity
Journal Article
Drug design, development and therapy, ISSN 1177-8881, 08/2015, Volume 9, pp. 4761 - 4778
The immune system is the defense mechanism in living organisms that protects against the invasion of foreign materials, microorganisms, and pathogens. It... 
T-cells | Macrophages | Neutrophils | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Lymphocytes - metabolism | Blood Platelets - immunology | Dendritic Cells - immunology | Humans | Immune System - pathology | Animals | Lymphocytes - immunology | Granulocytes - drug effects | Blood Platelets - metabolism | Immune System - metabolism | Immune System - drug effects | Lymphocytes - drug effects | Chalcones - therapeutic use | Immune System - immunology | Dendritic Cells - drug effects | Granulocytes - metabolism | Blood Platelets - drug effects | Dendritic Cells - metabolism | Granulocytes - immunology | Immunologic Factors - therapeutic use | Drugs | Pharmacology, Experimental | Ketones | Structure-activity relationship (Pharmacology) | Research | Properties | Structure-activity relationships | Immune system | Testing | Cell proliferation | Multiple sclerosis | Leukocyte migration | Chemical stimuli | Mucosa | Antibodies | Gram-positive bacteria | Cytotoxicity | Lymphocytes T | Infections | Lymph nodes | Anticancer properties | Proteins | Microorganisms | Immunology | Lymphocytes | Atherosclerosis | Antiviral activity | Spleen | Medical research | Enzymes | Pathogens | Antigens | Immunoglobulins | Cytokines | Dendritic cells | Immunomodulation | Therapeutic applications | Organs | Adaptive immunity | Inflammation | Lymphoid tissue | Derivatives | Cell differentiation | Defense | Tuberculosis | Lymphocytes B | Arteriosclerosis | Autoimmune diseases | Leukocytes (granulocytic) | Cell migration | Index Medicus | neutrophils | macrophages
Journal Article
Research on chemical intermediates, ISSN 0922-6168, 1/2018, Volume 44, Issue 1, pp. 455 - 467
...)phenyl)prop-2-en-1-one derivatives 6a–j were synthesized in click chemistry reaction conditions and evaluated... 
Docking studies | Chemistry | Cyclooxygenase | Physical Chemistry | Imidazole | Catalysis | Inorganic Chemistry | 1,2,3-Triazole | Chalcone | Proteins | Phenols | COX-2 inhibitors | Indomethacin | Triazoles | Ibuprofen | Binding | Derivatives | Chemical synthesis | Molecular docking
Journal Article